Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Blastomyces dermatitidis ER-3
Locus:
BDCG_00301
Length:
642
Number of sequences:
9522
Description:
actin-bundling protein Sac6
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P11531    3678   DMD_MOUSE Dystrophin OS=Mus musculus (Mouse)....2770.001     46.2     25     41GO:0030055; C:cell-substrate junction; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016010; C:dystrophin-associated glycoprotein complex; IDA:MGI.::GO:0045121; C:membrane raft; IDA:MGI.::GO:0005792; C:microsome; IDA:MGI.::GO:0044306; C:neuron projection terminus; IDA:MGI.::GO:0042383; C:sarcolemma; IDA:MGI.::GO:0045202; C:synapse; IDA:MGI.::GO:0030018; C:Z disc; IDA:MGI.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0050998; F:nitric-oxide synthase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046716; P:muscle cell homeostasis; IMP:MGI.::GO:0045213; P:neurotransmitter receptor metabolic process; IMP:MGI.::GO:0021629; P:olfactory nerve structural organization; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:MGI.::GO:0007519; P:skeletal muscle tissue development; IMP:MGI.
32P11532    3685   DMD_HUMAN Dystrophin OS=Homo sapiens (Human)....2760.003     44.7     26     40GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0043034; C:costamere; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016010; C:dystrophin-associated glycoprotein complex; IDA:UniProtKB.::GO:0042383; C:sarcolemma; IDA:BHF-UCL.
GO:0003779; F:actin binding; TAS:UniProtKB.::GO:0002162; F:dystroglycan binding; IPI:UniProtKB.::GO:0050998; F:nitric-oxide synthase binding; ISS:BHF-UCL.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0008307; F:structural constituent of muscle; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0043043; P:peptide biosynthetic process; IDA:UniProtKB.
33O97592    3680   DMD_CANFA Dystrophin OS=Canis familiaris (Dog...2020.002     45.1     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
34Q8NF91    8797   SYNE1_HUMAN Nesprin-1 OS=Homo sapiens (Human)...1300.014     42.7     26     48GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IDA:UniProtKB.::GO:0030017; C:sarcomere; IDA:MGI.::GO:0034993; C:SUN-KASH complex; IDA:UniProtKB.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0005521; F:lamin binding; IPI:UniProtKB.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0090286; P:cytoskeletal anchoring at nuclear membrane; IDA:UniProtKB.::GO:0007030; P:Golgi organization; IDA:UniProtKB.::GO:0042692; P:muscle cell differentiation; IDA:UniProtKB.::GO:0090292; P:nuclear matrix anchoring at nuclear membrane; IDA:UniProtKB.
35P11533    3660   DMD_CHICK Dystrophin OS=Gallus gallus (Chicke...2710.0002     48.5     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
36Q5GN48    3674   DMD_PIG Dystrophin OS=Sus scrofa (Pig). GN=DM...2850.0006     47     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
37Q15149    4684   PLEC_HUMAN Plectin OS=Homo sapiens (Human). G...2380.076     40     20     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0030056; C:hemidesmosome; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0042383; C:sarcolemma; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB.
38Q9H254    2564   SPTN4_HUMAN Spectrin beta chain, brain 3 OS=H...2670.0006     47     22     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0008091; C:spectrin; IDA:UniProtKB.
GO:0003779; F:actin binding; TAS:UniProtKB.::GO:0030506; F:ankyrin binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB.
GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; TAS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB.
39Q9QXS1    4691   PLEC_MOUSE Plectin OS=Mus musculus (Mouse). G...2270.43     37.7     20     42GO:0043292; C:contractile fiber; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; ISS:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:MGI.::GO:0042383; C:sarcolemma; ISS:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0031581; P:hemidesmosome assembly; ISS:UniProtKB.
40Q6ZWR6    8799   SYNE1_MOUSE Nesprin-1 OS=Mus musculus (Mouse)...1120.14     39.3     27     48GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell.::GO:0030017; C:sarcomere; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0040023; P:establishment of nucleus localization; IMP:MGI.
41P30427    4687   PLEC_RAT Plectin OS=Rattus norvegicus (Rat). ...2380.079     40     20     42GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0042383; C:sarcolemma; IDA:RGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0005200; F:structural constituent of cytoskeleton; IMP:RGD.
GO:0030855; P:epithelial cell differentiation; IEP:RGD.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0031581; P:hemidesmosome assembly; ISS:UniProtKB.::GO:0007584; P:response to nutrient; IDA:RGD.
42P13466    857   GELA_DICDI Gelation factor OS=Dictyostelium d...1070.0002     48.1     32     45GO:0030864; C:cortical actin cytoskeleton; IDA:dictyBase.::GO:0005624; C:membrane fraction; IDA:dictyBase.::GO:0001891; C:phagocytic cup; IDA:dictyBase.
GO:0051015; F:actin filament binding; TAS:dictyBase.::GO:0042803; F:protein homodimerization activity; TAS:dictyBase.
GO:0030036; P:actin cytoskeleton organization; IDA:dictyBase.::GO:0006972; P:hyperosmotic response; IEP:dictyBase.::GO:0042331; P:phototaxis; IMP:dictyBase.::GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0043052; P:thermotaxis; IMP:dictyBase.
43Q00963    2291   SPTCB_DROME Spectrin beta chain OS=Drosophila...2660.033     41.2     23     40GO:0016327; C:apicolateral plasma membrane; TAS:FlyBase.::GO:0030424; C:axon; IDA:FlyBase.::GO:0045169; C:fusome; IDA:FlyBase.::GO:0016328; C:lateral plasma membrane; IDA:FlyBase.::GO:0031594; C:neuromuscular junction; IDA:FlyBase.::GO:0008091; C:spectrin; IEA:InterPro.::GO:0045170; C:spectrosome; IDA:FlyBase.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0030506; F:ankyrin binding; IDA:FlyBase.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:FlyBase.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:FlyBase.::GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0016199; P:axon midline choice point recognition; IMP:FlyBase.::GO:0045478; P:fusome organization; TAS:FlyBase.::GO:0042062; P:long-term strengthening of neuromuscular junction; IMP:FlyBase.::GO:0048790; P:maintenance of presynaptic active zone structure; IDA:FlyBase.::GO:0007026; P:negative regulation of microtubule depolymerization; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IMP:FlyBase.::GO:0072499; P:photoreceptor cell axon guidance; IMP:FlyBase.::GO:0007009; P:plasma membrane organization; TAS:FlyBase.::GO:0030721; P:spectrosome organization; TAS:FlyBase.
44O13728    621   AIN1_SCHPO Alpha-actinin-like protein 1 OS=Sc...1420.006     43.5     27     40GO:0005826; C:actomyosin contractile ring; IDA:PomBase.
GO:0003779; F:actin binding; TAS:PomBase.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; TAS:PomBase.
GO:0051764; P:actin crosslink formation; TAS:PomBase.::GO:0051017; P:actin filament bundle assembly; TAS:PomBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.
45O76329    1738   ACTNB_DICDI Interaptin OS=Dictyostelium disco...2410.00001     52.4     27     44GO:0005813; C:centrosome; IDA:dictyBase.::GO:0005789; C:endoplasmic reticulum membrane; IDA:dictyBase.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; ISS:dictyBase.
GO:0016337; P:cell-cell adhesion; IMP:dictyBase.::GO:0007275; P:multicellular organismal development; IMP:dictyBase.::GO:0009847; P:spore germination; IMP:dictyBase.
46Q9VDW6    3598   DMDA_DROME Dystrophin, isoforms A/C/F/G/H OS=...1340.11     39.7     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0016010; C:dystrophin-associated glycoprotein complex; IPI:FlyBase.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0050699; F:WW domain binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030010; P:establishment of cell polarity; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:UniProtKB.::GO:0046716; P:muscle cell homeostasis; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:UniProtKB.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IDA:FlyBase.
47Q7PKQ5    922   ACTN_ANOGA Alpha-actinin, sarcomeric OS=Anoph...2390.0005     47     22     42
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
48P18091    924   ACTN_DROME Alpha-actinin, sarcomeric OS=Droso...1860.001     45.8     23     42GO:0030018; C:Z disc; IDA:FlyBase.
GO:0003779; F:actin binding; IPI:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; IMP:FlyBase.::GO:0007629; P:flight behavior; IMP:FlyBase.::GO:0045214; P:sarcomere organization; IMP:FlyBase.
49Q8C5W0    1052   CLMN_MOUSE Calmin OS=Mus musculus (Mouse). GN...1220.00008     49.7     32     50GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.::GO:0031175; P:neuron projection development; IMP:MGI.
50Q9JI91    894   ACTN2_MOUSE Alpha-actinin-2 OS=Mus musculus (...1900.023     41.6     25     43GO:0005865; C:striated muscle thin filament; TAS:MGI.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0051015; F:actin filament binding; IDA:MGI.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; TAS:MGI.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.::GO:0030375; F:thyroid hormone receptor coactivator activity; IDA:MGI.::GO:0051370; F:ZASP binding; IDA:UniProtKB.
GO:0006936; P:muscle contraction; IPI:MGI.
51Q3ZC55    894   ACTN2_BOVIN Alpha-actinin-2 OS=Bos taurus (Bo...1900.021     41.6     25     43GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
52P35609    894   ACTN2_HUMAN Alpha-actinin-2 OS=Homo sapiens (...1900.023     41.6     25     43GO:0005884; C:actin filament; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043197; C:dendritic spine; TAS:UniProtKB.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IMP:UniProtKB.::GO:0031093; C:platelet alpha granule lumen; TAS:Reactome.::GO:0031143; C:pseudopodium; TAS:UniProtKB.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051373; F:FATZ binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0005178; F:integrin binding; TAS:UniProtKB.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0046983; F:protein dimerization activity; IDA:UniProtKB.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.::GO:0031432; F:titin binding; IDA:BHF-UCL.::GO:0070080; F:titin Z domain binding; IPI:BHF-UCL.::GO:0051370; F:ZASP binding; IDA:UniProtKB.
GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0030035; P:microspike assembly; IDA:UniProtKB.::GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
53P20111    897   ACTN2_CHICK Alpha-actinin-2 OS=Gallus gallus ...1900.055     40.4     25     43GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030018; C:Z disc; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0030035; P:microspike assembly; IDA:UniProtKB.
54Q6ZWQ0    6874   SYNE2_MOUSE Nesprin-2 OS=Mus musculus (Mouse)...2773.9     34.7     23     39GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:UniProtKB.
GO:0051642; P:centrosome localization; IMP:UniProtKB.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.::GO:0010761; P:fibroblast migration; IMP:MGI.::GO:0006998; P:nuclear envelope organization; IMP:MGI.::GO:0031022; P:nuclear migration along microfilament; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0034504; P:protein localization to nucleus; IMP:MGI.
55Q8VHX6    2726   FLNC_MOUSE Filamin-C OS=Mus musculus (Mouse)....1030.083     40     32     45GO:0015629; C:actin cytoskeleton; TAS:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; TAS:MGI.
GO:0030029; P:actin filament-based process; TAS:MGI.::GO:0048747; P:muscle fiber development; IDA:UniProtKB.
56Q08043    901   ACTN3_HUMAN Alpha-actinin-3 OS=Homo sapiens (...3080.001     46.2     24     41GO:0005884; C:actin filament; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IMP:UniProtKB.::GO:0031143; C:pseudopodium; TAS:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005178; F:integrin binding; TAS:UniProtKB.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
57Q96JQ2    1002   CLMN_HUMAN Calmin OS=Homo sapiens (Human). GN...1090.0003     47.8     32     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
58O88990    900   ACTN3_MOUSE Alpha-actinin-3 OS=Mus musculus (...3070.0009     46.2     24     41GO:0005865; C:striated muscle thin filament; TAS:MGI.
GO:0051015; F:actin filament binding; IDA:MGI.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; TAS:MGI.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
GO:0006936; P:muscle contraction; IPI:MGI.
59Q0III9    901   ACTN3_BOVIN Alpha-actinin-3 OS=Bos taurus (Bo...3080.0008     46.2     24     41
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
60Q14315    2725   FLNC_HUMAN Filamin-C OS=Homo sapiens (Human)....1030.081     40     32     45GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0034329; P:cell junction assembly; TAS:Reactome.
61A5D7D1    911   ACTN4_BOVIN Alpha-actinin-4 OS=Bos taurus (Bo...2370.061     40.4     22     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
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