rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
991 | O70589 | 926 | CSKP_MOUSE Peripheral plasma membrane protein... | 270 | 1e-27 | 119 | 27 | 50 | GO:0016323; C:basolateral plasma membrane; IDA:MGI.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0045202; C:synapse; IDA:MGI.::GO:0019717; C:synaptosome; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI. | 992 | O45818 | 1070 | DKF2_CAEEL Serine/threonine-protein kinase dk... | 342 | 2e-27 | 119 | 29 | 47 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0016020; C:membrane; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.::GO:0050830; P:defense response to Gram-positive bacterium; IMP:WormBase.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0045089; P:positive regulation of innate immune response; IMP:WormBase. | 993 | O14936 | 926 | CSKP_HUMAN Peripheral plasma membrane protein... | 270 | 2e-27 | 119 | 27 | 50 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0060170; C:cilium membrane; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005652; C:nuclear lamina; IDA:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0005730; C:nucleolus; IDA:BHF-UCL.::GO:0042734; C:presynaptic membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004385; F:guanylate kinase activity; TAS:ProtInc.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0001953; P:negative regulation of cell-matrix adhesion; IMP:BHF-UCL.::GO:0090288; P:negative regulation of cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0010839; P:negative regulation of keratinocyte proliferation; IMP:BHF-UCL.::GO:0061045; P:negative regulation of wound healing; IMP:BHF-UCL. | 994 | B5VNQ3 | 717 | STE11_YEAS6 Serine/threonine-protein kinase S... | 304 | 2e-27 | 118 | 26 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 995 | Q62915 | 909 | CSKP_RAT Peripheral plasma membrane protein C... | 270 | 2e-27 | 119 | 27 | 50 | GO:0060170; C:cilium membrane; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0042734; C:presynaptic membrane; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; TAS:RGD.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IMP:RGD.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; TAS:RGD. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IMP:RGD.::GO:0006461; P:protein complex assembly; TAS:RGD. | 996 | Q8IVH8 | 894 | M4K3_HUMAN Mitogen-activated protein kinase k... | 268 | 2e-27 | 118 | 29 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc. | 997 | Q03497 | 939 | STE20_YEAST Serine/threonine-protein kinase S... | 261 | 2e-27 | 118 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035174; F:histone serine kinase activity; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008349; F:MAP kinase kinase kinase kinase activity; IDA:SGD. | | | | | | | | | | GO:0000282; P:cellular bud site selection; IMP:SGD.::GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0010629; P:negative regulation of gene expression; IMP:SGD.::GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD.::GO:0035376; P:sterol import; IMP:SGD.::GO:0034063; P:stress granule assembly; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD. | 998 | Q5UQG7 | 1651 | YR818_MIMIV Putative serine/threonine-protein... | 203 | 0.00000000000003 | 78.2 | 27 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016849; F:phosphorus-oxygen lyase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 999 | P49615 | 292 | CDK5_MOUSE Cyclin-dependent kinase 5 OS=Mus m... | 287 | 2e-27 | 114 | 30 | 47 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030549; F:acetylcholine receptor activator activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; IDA:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:MGI.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0048148; P:behavioral response to cocaine; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; IDA:MGI.::GO:0021954; P:central nervous system neuron development; IMP:MGI.::GO:0021697; P:cerebellar cortex formation; IMP:MGI.::GO:0022038; P:corpus callosum development; IMP:MGI.::GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0006886; P:intracellular protein transport; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IMP:MGI.::GO:0008045; P:motor axon guidance; IMP:MGI.::GO:0045786; P:negative regulation of cell cycle; IMP:MGI.::GO:0046826; P:negative regulation of protein export from nucleus; IMP:MGI.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:MGI.::GO:0031914; P:negative regulation of synaptic plasticity; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:MGI.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; IMP:MGI.::GO:0032801; P:receptor catabolic process; IMP:MGI.::GO:0043113; P:receptor clustering; IMP:MGI.::GO:0030334; P:regulation of cell migration; IMP:MGI.::GO:0061001; P:regulation of dendritic spine morphogenesis; IMP:UniProtKB.::GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IMP:MGI.::GO:0014044; P:Schwann cell development; IMP:MGI.::GO:0019233; P:sensory perception of pain; IMP:MGI.::GO:0033136; P:serine phosphorylation of STAT3 protein; IDA:MGI.::GO:0007519; P:skeletal muscle tissue development; IDA:MGI.::GO:0001963; P:synaptic transmission, dopaminergic; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI. | 1000 | Q02399 | 292 | CDK5_BOVIN Cyclin-dependent kinase 5 OS=Bos t... | 287 | 2e-27 | 114 | 30 | 47 | GO:0030424; C:axon; ISS:AgBase.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:AgBase.::GO:0030175; C:filopodium; ISS:AgBase.::GO:0030426; C:growth cone; ISS:AgBase.::GO:0030027; C:lamellipodium; ISS:AgBase.::GO:0031594; C:neuromuscular junction; ISS:AgBase.::GO:0005634; C:nucleus; ISS:AgBase.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030549; F:acetylcholine receptor activator activity; ISS:AgBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:AgBase.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; TAS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:AgBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; ISS:AgBase.::GO:0009790; P:embryo development; ISS:AgBase.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:AgBase.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB. |