Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Blastomyces dermatitidis ER-3
Locus:
BDCG_00277
Length:
589
Number of sequences:
9522
Description:
leukotriene A4 hydrolase
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q3SZH7    611   LKHA4_BOVIN Leukotriene A-4 hydrolase OS=Bos ...5728e-147     444     42     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; ISS:UniProtKB.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
32Q6S9C8    611   LKHA4_CHILA Leukotriene A-4 hydrolase OS=Chin...5693e-146     442     41     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; ISS:UniProtKB.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
33Q59NB8    623   LKHA4_CANAL Leukotriene A-4 hydrolase homolog...6082e-143     436     42     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; IEA:EC.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0019370; P:leukotriene biosynthetic process; IEA:UniProtKB-KW.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
34P19602    611   LKHA4_CAVPO Leukotriene A-4 hydrolase OS=Cavi...5661e-141     431     40     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; ISS:UniProtKB.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
35P30349    610   LKHA4_RAT Leukotriene A-4 hydrolase OS=Rattus...5694e-141     429     41     62GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; IDA:RGD.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.::GO:0010043; P:response to zinc ion; IEP:RGD.::GO:0060509; P:Type I pneumocyte differentiation; IEP:RGD.
36P52922    606   LKHA4_DICDI Leukotriene A-4 hydrolase homolog...5535e-130     400     41     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; IEA:EC.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0019370; P:leukotriene biosynthetic process; IEA:UniProtKB-KW.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
37Q75B10    623   LKHA4_ASHGO Leukotriene A-4 hydrolase homolog...5817e-130     401     39     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; IEA:EC.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0019370; P:leukotriene biosynthetic process; IEA:UniProtKB-KW.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
38Q8VCT3    650   AMPB_MOUSE Aminopeptidase B OS=Mus musculus (...5355e-91     300     34     52
GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
39O09175    650   AMPB_RAT Aminopeptidase B OS=Rattus norvegicu...5352e-90     298     34     52GO:0009897; C:external side of plasma membrane; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0005794; C:Golgi apparatus; NAS:UniProtKB.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0050897; F:cobalt ion binding; IDA:RGD.::GO:0005507; F:copper ion binding; IDA:RGD.::GO:0070006; F:metalloaminopeptidase activity; IDA:RGD.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0007568; P:aging; IEP:RGD.::GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0045776; P:negative regulation of blood pressure; IMP:RGD.::GO:0016485; P:protein processing; NAS:UniProtKB.::GO:0006508; P:proteolysis; IC:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IEP:RGD.
40Q9H4A4    650   AMPB_HUMAN Aminopeptidase B OS=Homo sapiens (...5352e-88     293     34     52
GO:0004301; F:epoxide hydrolase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0006508; P:proteolysis; IC:UniProtKB.
41Q9HAU8    494   RNPL1_HUMAN Arginyl aminopeptidase-like 1 OS=...4496e-61     216     32     50
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
42P95928    785   APE2_SULSO Leucyl aminopeptidase OS=P2). GN=a...3438e-21     100     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
43Q96ZT9    786   APE1_SULTO Probable aminopeptidase 1 OS=Sulfo...3631e-20     100     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
44Q10737    972   AMPN_HAECO Aminopeptidase N OS=Haemonchus con...3056e-19     94.7     29     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
45P55786    919   PSA_HUMAN Puromycin-sensitive aminopeptidase ...3016e-19     94.7     29     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; TAS:ProtInc.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.::GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
46Q11011    920   PSA_MOUSE Puromycin-sensitive aminopeptidase ...3011e-18     94     29     43GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
47Q97VF1    784   APE1_SULSO Probable aminopeptidase 1 OS=P2). ...3903e-18     92.4     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
48Q974N6    781   APE2_SULTO Probable aminopeptidase 2 OS=Sulfo...3219e-18     90.9     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
49Q978U3    783   TRF2_THEVO Tricorn protease-interacting facto...3921e-17     90.5     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
50P97629    1025   LCAP_RAT Leucyl-cystinyl aminopeptidase OS=Ra...4365e-17     88.6     25     40GO:0009986; C:cell surface; IDA:RGD.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0032593; C:insulin-responsive compartment; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0004177; F:aminopeptidase activity; IDA:RGD.::GO:0001595; F:angiotensin receptor activity; IMP:RGD.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0017046; F:peptide hormone binding; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010813; P:neuropeptide catabolic process; IMP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:RGD.::GO:0009725; P:response to hormone stimulus; IDA:RGD.
51P15145    963   AMPN_PIG Aminopeptidase N OS=Sus scrofa (Pig)...3407e-17     88.2     28     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
52P97449    966   AMPN_MOUSE Aminopeptidase N OS=Mus musculus (...3091e-16     87.8     27     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
53Q8SRG3    864   AMP12_ENCCU Probable M1 family aminopeptidase...3071e-16     87.4     26     42
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
54Q8C129    1025   LCAP_MOUSE Leucyl-cystinyl aminopeptidase OS=...4361e-16     87.4     25     40GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0004177; F:aminopeptidase activity; IMP:MGI.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IMP:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
55Q97AJ6    779   TRF3_THEVO Tricorn protease-interacting facto...3832e-16     86.7     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
56P79171    967   AMPN_FELCA Aminopeptidase N OS=Felis catus (C...3062e-16     86.7     28     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
57P15684    965   AMPN_RAT Aminopeptidase N OS=Rattus norvegicu...3552e-16     86.7     26     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0031983; C:vesicle lumen; IDA:RGD.::GO:0012506; C:vesicle membrane; IDA:RGD.
GO:0004177; F:aminopeptidase activity; IDA:RGD.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006725; P:cellular aromatic compound metabolic process; IDA:RGD.::GO:0035814; P:negative regulation of renal sodium excretion; IMP:RGD.::GO:0006508; P:proteolysis; IDA:RGD.
58P69527    816   AMPO_RAT Aminopeptidase O OS=Rattus norvegicu...4852e-16     86.3     22     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0006508; P:proteolysis; ISS:UniProtKB.
59Q8SQI6    864   AMP11_ENCCU Probable M1 family aminopeptidase...3073e-16     85.9     26     42
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
60Q9UIQ6    1025   LCAP_HUMAN Leucyl-cystinyl aminopeptidase OS=...3417e-16     85.1     26     41GO:0005829; C:cytosol; TAS:Reactome.::GO:0031905; C:early endosome lumen; TAS:Reactome.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0004177; F:aminopeptidase activity; TAS:HGNC.::GO:0008237; F:metallopeptidase activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007565; P:female pregnancy; TAS:ProtInc.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006508; P:proteolysis; TAS:ProtInc.
61A6NEC2    478   PSAL_HUMAN Puromycin-sensitive aminopeptidase...3050.000000000000001     83.6     27     41
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
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