rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
451 | Q91ZT8 | 290 | ASB9_MOUSE Ankyrin repeat and SOCS box protei... | 81 | 2.1 | 35 | 27 | 48 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 452 | Q8H569 | 907 | AKT3_ORYSJ Potassium channel AKT3 OS=Oryza sa... | 183 | 0.00001 | 52.4 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 453 | Q9M8S6 | 828 | SKOR_ARATH Potassium channel SKOR OS=Arabidop... | 213 | 0.0005 | 47.4 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015271; F:outward rectifier potassium channel activity; IDA:TAIR. | | | | | | | | | | | 454 | Q6NSI1 | 321 | AR26L_HUMAN Putative ankyrin repeat domain-co... | 134 | 0.00004 | 49.7 | 28 | 48 | | | | | | | | | | | | | | | | | | | | | | 455 | P25963 | 317 | IKBA_HUMAN NF-kappa-B inhibitor alpha OS=Homo... | 74 | 0.17 | 38.5 | 36 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0033256; C:I-kappaB/NF-kappaB complex; TAS:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0008139; F:nuclear localization sequence binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0070417; P:cellular response to cold; NAS:BHF-UCL.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IMP:BHF-UCL.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043392; P:negative regulation of DNA binding; NAS:UniProtKB.::GO:0010888; P:negative regulation of lipid storage; IMP:BHF-UCL.::GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0032270; P:positive regulation of cellular protein metabolic process; IMP:BHF-UCL.::GO:0010875; P:positive regulation of cholesterol efflux; IMP:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 456 | Q5ZMD2 | 460 | ANKY2_CHICK Ankyrin repeat and MYND domain-co... | 91 | 0.018 | 42 | 34 | 51 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 457 | Q6NY19 | 840 | KANK3_HUMAN KN motif and ankyrin repeat domai... | 153 | 1.2 | 36.2 | 29 | 44 | | | | | | | | | | | | | | | | | | | | | | 458 | A9JR78 | 1427 | TONSL_DANRE Tonsoku-like protein OS=Danio rer... | 124 | 1.5 | 36.2 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043596; C:nuclear replication fork; ISS:UniProtKB. | | | | | | | | | | GO:0042393; F:histone binding; ISS:UniProtKB. | | | | | | | | | | GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0031297; P:replication fork processing; ISS:UniProtKB. | 459 | Q5R5V4 | 452 | ILK_PONAB Integrin-linked protein kinase OS=P... | 163 | 1.2 | 36.2 | 24 | 39 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 460 | P13508 | 1295 | GLP1_CAEEL Protein glp-1 OS=Caenorhabditis el... | 185 | 0.000008 | 53.1 | 28 | 46 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0012505; C:endomembrane system; IDA:WormBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016328; C:lateral plasma membrane; IDA:WormBase. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0001708; P:cell fate specification; IGI:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0043055; P:maintenance of dauer; IGI:WormBase.::GO:0007219; P:Notch signaling pathway; IEA:InterPro.::GO:0043282; P:pharyngeal muscle development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0042127; P:regulation of cell proliferation; IMP:WormBase.::GO:0040020; P:regulation of meiosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 461 | Q8BG95 | 976 | MYPT2_MOUSE Protein phosphatase 1 regulatory ... | 228 | 0.000008 | 53.1 | 27 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 462 | Q13418 | 452 | ILK_HUMAN Integrin-linked protein kinase OS=H... | 163 | 1.1 | 36.2 | 24 | 39 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB. | 463 | Q3SWY2 | 452 | ILK_BOVIN Integrin-linked protein kinase OS=B... | 163 | 1.7 | 35.4 | 24 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 464 | O74205 | 441 | TOXE_COCCA Transcription factor TOXE OS=Cochl... | 90 | 0.089 | 39.7 | 30 | 46 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0009403; P:toxin biosynthetic process; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 465 | P57044 | 451 | ILK_CAVPO Integrin-linked protein kinase OS=C... | 50 | 2.2 | 35 | 36 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 466 | Q99J82 | 452 | ILK_RAT Integrin-linked protein kinase OS=Rat... | 163 | 1.2 | 36.2 | 24 | 39 | GO:0005911; C:cell-cell junction; IDA:RGD.::GO:0043034; C:costamere; IDA:RGD.::GO:0043198; C:dendritic shaft; IDA:RGD.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0017124; F:SH3 domain binding; IDA:RGD.::GO:0004871; F:signal transducer activity; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IMP:RGD.::GO:0007050; P:cell cycle arrest; IMP:RGD.::GO:0043206; P:fibril organization; IMP:RGD.::GO:0007229; P:integrin-mediated signaling pathway; IMP:RGD.::GO:0032288; P:myelin assembly; IMP:RGD.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0006469; P:negative regulation of protein kinase activity; IMP:RGD.::GO:0014912; P:negative regulation of smooth muscle cell migration; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0043410; P:positive regulation of MAPK cascade; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:RGD.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:RGD. | 467 | O55222 | 452 | ILK_MOUSE Integrin-linked protein kinase OS=M... | 163 | 1.2 | 36.2 | 24 | 39 | GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001658; P:branching involved in ureteric bud morphogenesis; IDA:MGI.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IMP:MGI.::GO:0030513; P:positive regulation of BMP signaling pathway; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL. | 468 | P19838 | 968 | NFKB1_HUMAN Nuclear factor NF-kappa-B p105 su... | 153 | 0.00001 | 52.8 | 31 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0033256; C:I-kappaB/NF-kappaB complex; TAS:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071347; P:cellular response to interleukin-1; IEP:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0032269; P:negative regulation of cellular protein metabolic process; IC:BHF-UCL.::GO:0032375; P:negative regulation of cholesterol transport; IC:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0010957; P:negative regulation of vitamin D biosynthetic process; IC:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:1900127; P:positive regulation of hyaluronan biosynthetic process; IDA:UniProtKB.::GO:0010884; P:positive regulation of lipid storage; IC:BHF-UCL.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:UniProtKB.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 469 | Q66JD7 | 286 | ACBD6_XENTR Acyl-CoA-binding domain-containin... | 87 | 0.0002 | 47.4 | 32 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro. | | | | | | | | | | | 470 | O60237 | 982 | MYPT2_HUMAN Protein phosphatase 1 regulatory ... | 276 | 0.00001 | 52.8 | 25 | 39 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0008047; F:enzyme activator activity; TAS:ProtInc. | | | | | | | | | | GO:0006937; P:regulation of muscle contraction; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc. | 471 | A2ARS0 | 390 | ANR63_MOUSE Ankyrin repeat domain-containing ... | 69 | 0.085 | 39.7 | 32 | 51 | | | | | | | | | | | | | | | | | | | | | | 472 | Q5URB8 | 601 | YR841_MIMIV Putative ankyrin repeat protein R... | 144 | 1.1 | 36.2 | 25 | 39 | | | | | | | | | | | | | | | | | | | | | | 473 | Q04749 | 426 | AVO2_YEAST Target of rapamycin complex 2 subu... | 157 | 0.014 | 42.4 | 27 | 46 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031932; C:TORC2 complex; IPI:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0001558; P:regulation of cell growth; IPI:SGD.::GO:0031929; P:TOR signaling cascade; IC:SGD. | 474 | Q6DRG7 | 1049 | MYPT1_DANRE Protein phosphatase 1 regulatory ... | 227 | 0.00001 | 52.8 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0019208; F:phosphatase regulator activity; ISS:UniProtKB. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IMP:ZFIN.::GO:0001889; P:liver development; IMP:ZFIN.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB. | 475 | Q96DX5 | 294 | ASB9_HUMAN Ankyrin repeat and SOCS box protei... | 81 | 1.7 | 35.4 | 28 | 49 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0016567; P:protein ubiquitination; IDA:MGI. | 476 | Q810B6 | 1169 | ANFY1_MOUSE Ankyrin repeat and FYVE domain-co... | 195 | 7.3 | 33.9 | 23 | 41 | GO:0010008; C:endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:UniProtKB. | 477 | Q99728 | 777 | BARD1_HUMAN BRCA1-associated RING domain prot... | 119 | 0.025 | 41.6 | 29 | 49 | GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; NAS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0031441; P:negative regulation of mRNA 3'-end processing; NAS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; NAS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; TAS:UniProtKB. | 478 | Q8WXE0 | 1202 | CSKI2_HUMAN Caskin-2 OS=Homo sapiens (Human).... | 245 | 0.00004 | 51.2 | 24 | 38 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 479 | Q7T2B9 | 118 | MTPN_DANRE Myotrophin OS=Danio rerio (Zebrafi... | 62 | 1.1 | 34.3 | 34 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 480 | Q9ULT8 | 2610 | HECD1_HUMAN E3 ubiquitin-protein ligase HECTD... | 135 | 0.027 | 42 | 26 | 39 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 481 | Q9CQ31 | 323 | ASB11_MOUSE Ankyrin repeat and SOCS box prote... | 121 | 0.31 | 37.7 | 26 | 42 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. |