rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
991 | P42681 | 527 | TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo... | 139 | 0.00000002 | 62 | 29 | 52 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.::GO:0001012; F:RNA polymerase II regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; ISS:UniProtKB.::GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0032729; P:positive regulation of interferon-gamma production; IDA:UniProtKB.::GO:0060335; P:positive regulation of interferon-gamma-mediated signaling pathway; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 992 | Q2H332 | 360 | HOG1_CHAGB Mitogen-activated protein kinase H... | 169 | 0.00000002 | 61.2 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 993 | Q11112 | 328 | YX05_CAEEL Putative tyrosine-protein kinase C... | 86 | 0.00000002 | 60.8 | 36 | 62 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 994 | Q61084 | 626 | M3K3_MOUSE Mitogen-activated protein kinase k... | 297 | 0.00000002 | 62 | 25 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 995 | P29319 | 983 | EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus m... | 139 | 0.00000002 | 62.4 | 30 | 54 | GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0003197; P:endocardial cushion development; IMP:UniProtKB.::GO:0097156; P:fasciculation of motor neuron axon; IMP:UniProtKB.::GO:0097155; P:fasciculation of sensory neuron axon; IMP:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0010717; P:regulation of epithelial to mesenchymal transition; IMP:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0070507; P:regulation of microtubule cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 996 | P16912 | 583 | KDC2_DROME Protein kinase DC2 OS=Drosophila m... | 140 | 0.00000002 | 62 | 29 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase. | 997 | P13186 | 1147 | KIN2_YEAST Serine/threonine-protein kinase KI... | 332 | 0.00000002 | 62.4 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:SGD. | 998 | O61267 | 476 | LOK_DROME Ovarian-specific serine/threonine-p... | 189 | 0.00000002 | 61.6 | 31 | 52 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0000077; P:DNA damage checkpoint; IDA:FlyBase.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:BHF-UCL.::GO:0007281; P:germ cell development; IEP:UniProtKB.::GO:0035234; P:germ cell programmed cell death; IMP:FlyBase.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:BHF-UCL. | 999 | Q02111 | 707 | KPCT_MOUSE Protein kinase C theta type OS=Mus... | 86 | 0.00000002 | 62 | 37 | 60 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001772; C:immunological synapse; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; IDA:MGI. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006509; P:membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; ISS:UniProtKB.::GO:0032740; P:positive regulation of interleukin-17 production; IMP:UniProtKB.::GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IMP:MGI.::GO:0032753; P:positive regulation of interleukin-4 production; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:2000318; P:positive regulation of T-helper 17 type immune response; IMP:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB. | 1000 | Q5REX1 | 925 | SIK2_PONAB Serine/threonine-protein kinase SI... | 190 | 0.00000003 | 62 | 26 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB. |