rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q9H4B4 | 646 | PLK3_HUMAN Serine/threonine-protein kinase PL... | 232 | 0.000000000003 | 74.7 | 28 | 45 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0007113; P:endomitotic cell cycle; TAS:UniProtKB.::GO:0071779; P:G1/S transition checkpoint; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0090166; P:Golgi disassembly; IDA:UniProtKB.::GO:0071780; P:mitotic cell cycle G2/M transition checkpoint; TAS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:2000777; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; IDA:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0006970; P:response to osmotic stress; IDA:UniProtKB.::GO:0009314; P:response to radiation; IDA:UniProtKB.::GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; IMP:UniProtKB. | 182 | Q54QI2 | 941 | Y9877_DICDI Serine/threonine-protein kinase D... | 219 | 0.000000000003 | 74.7 | 27 | 44 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 183 | Q32MK0 | 819 | MYLK3_HUMAN Putative myosin light chain kinas... | 233 | 0.000000000003 | 74.7 | 25 | 46 | GO:0005829; C:cytosol; ISS:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:BHF-UCL.::GO:0004687; F:myosin light chain kinase activity; ISS:BHF-UCL. | | | | | | | | | | GO:0055003; P:cardiac myofibril assembly; ISS:BHF-UCL.::GO:0071347; P:cellular response to interleukin-1; IMP:BHF-UCL.::GO:0060298; P:positive regulation of sarcomere organization; ISS:BHF-UCL.::GO:0002528; P:regulation of vascular permeability involved in acute inflammatory response; IMP:BHF-UCL.::GO:0045214; P:sarcomere organization; ISS:BHF-UCL.::GO:0048769; P:sarcomerogenesis; ISS:BHF-UCL. | 184 | Q2VWQ3 | 642 | STE20_PENMA Serine/threonine-protein kinase p... | 150 | 0.000000000003 | 74.3 | 29 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 185 | Q54ZN3 | 998 | Y0004_DICDI Probable protein kinase DDB_G0277... | 119 | 0.00002 | 52.4 | 32 | 46 | GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.::GO:0004713; F:protein tyrosine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0051726; P:regulation of cell cycle; ISS:dictyBase. | 186 | Q99JT2 | 416 | MST4_MOUSE Serine/threonine-protein kinase MS... | 149 | 0.000000000004 | 73.6 | 35 | 54 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB. | 187 | Q91ZR4 | 698 | NEK8_MOUSE Serine/threonine-protein kinase Ne... | 160 | 0.000000000004 | 74.3 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 188 | Q86SG6 | 692 | NEK8_HUMAN Serine/threonine-protein kinase Ne... | 160 | 0.000000000004 | 74.3 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 189 | Q3U214 | 1321 | MAST3_MOUSE Microtubule-associated serine/thr... | 257 | 0.000000000004 | 74.7 | 25 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 190 | Q863I2 | 529 | OXSR1_PIG Serine/threonine-protein kinase OSR... | 191 | 0.000000000004 | 73.9 | 29 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB. | 191 | P15442 | 1659 | GCN2_YEAST Serine/threonine-protein kinase GC... | 137 | 0.000000000004 | 74.7 | 31 | 48 | GO:0022626; C:cytosolic ribosome; IDA:SGD. | | | | | | | | | | GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:SGD.::GO:0000049; F:tRNA binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IMP:SGD.::GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.::GO:0006412; P:translation; IEA:UniProtKB-KW. | 192 | Q80ZW0 | 539 | STK35_MOUSE Serine/threonine-protein kinase 3... | 164 | 0.000000000004 | 73.9 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 193 | Q9Z1Z1 | 1108 | E2AK3_RAT Eukaryotic translation initiation f... | 134 | 0.000000000005 | 74.3 | 31 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031018; P:endocrine pancreas development; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0006983; P:ER overload response; ISS:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; TAS:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 194 | P83100 | 356 | MK14C_DROME Putative mitogen-activated protei... | 190 | 0.000000000005 | 72.8 | 29 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IGI:FlyBase. | 195 | B0WAU8 | 761 | PLK4_CULQU Serine/threonine-protein kinase PL... | 221 | 0.000000000005 | 74.3 | 26 | 43 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 196 | Q9JM01 | 593 | CDKL3_RAT Cyclin-dependent kinase-like 3 OS=R... | 158 | 0.000000000005 | 73.9 | 30 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 197 | Q9NGW9 | 714 | MKCB_DICDI Probable serine/threonine-protein ... | 178 | 0.000000000005 | 73.9 | 25 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 198 | P97477 | 395 | AURKA_MOUSE Aurora kinase A OS=Mus musculus (... | 172 | 0.000000000005 | 72.8 | 28 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 199 | Q9Z2B5 | 1114 | E2AK3_MOUSE Eukaryotic translation initiation... | 137 | 0.000000000005 | 74.3 | 31 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:MGI.::GO:0030282; P:bone mineralization; IMP:MGI.::GO:0019722; P:calcium-mediated signaling; IMP:MGI.::GO:0002063; P:chondrocyte development; IMP:MGI.::GO:0031018; P:endocrine pancreas development; ISS:UniProtKB.::GO:0007029; P:endoplasmic reticulum organization; IMP:MGI.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0006983; P:ER overload response; ISS:UniProtKB.::GO:0045444; P:fat cell differentiation; IDA:MGI.::GO:0030073; P:insulin secretion; IMP:MGI.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; IMP:MGI.::GO:0007595; P:lactation; IMP:MGI.::GO:0031642; P:negative regulation of myelination; IMP:MGI.::GO:0017148; P:negative regulation of translation; IDA:MGI.::GO:0032092; P:positive regulation of protein binding; IMP:MGI.::GO:0009967; P:positive regulation of signal transduction; IDA:MGI.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0019217; P:regulation of fatty acid metabolic process; IMP:MGI.::GO:0032933; P:SREBP-mediated signaling pathway; IDA:MGI.::GO:0006412; P:translation; IDA:MGI.::GO:0006926; P:virus-infected cell apoptotic process; IMP:MGI. | 200 | Q9NB31 | 497 | CST1_CAEEL Serine/threonine-protein kinase cs... | 151 | 0.000000000005 | 73.6 | 32 | 55 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:UniProtKB.::GO:0048747; P:muscle fiber development; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 201 | Q5RDG7 | 819 | MYLK3_PONAB Putative myosin light chain kinas... | 233 | 0.000000000005 | 73.9 | 25 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | | 202 | Q91447 | 388 | MP2K1_SERCA Dual specificity mitogen-activate... | 281 | 0.000000000005 | 72.8 | 25 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 203 | Q9UBS0 | 482 | KS6B2_HUMAN Ribosomal protein S6 kinase beta-... | 225 | 0.000000000006 | 73.2 | 24 | 47 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0006412; P:translation; TAS:ProtInc. | 204 | Q9MZD9 | 351 | KAPCA_SHEEP cAMP-dependent protein kinase cat... | 244 | 0.000000000006 | 72.4 | 25 | 45 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 205 | Q4KTY1 | 415 | KPSH1_PINFU Serine/threonine-protein kinase H... | 274 | 0.000000000006 | 72.8 | 26 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 206 | Q9NZJ5 | 1116 | E2AK3_HUMAN Eukaryotic translation initiation... | 134 | 0.000000000007 | 73.9 | 31 | 51 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0030282; P:bone mineralization; ISS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; ISS:UniProtKB.::GO:0002063; P:chondrocyte development; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; IMP:UniProtKB.::GO:0007029; P:endoplasmic reticulum organization; ISS:UniProtKB.::GO:0006983; P:ER overload response; IDA:UniProtKB.::GO:0030073; P:insulin secretion; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031642; P:negative regulation of myelination; ISS:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IMP:UniProtKB. | 207 | Q9JKV2 | 629 | ICK_MOUSE Serine/threonine-protein kinase ICK... | 151 | 0.000000000007 | 73.6 | 34 | 50 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 208 | Q08217 | 1101 | PSK2_YEAST Serine/threonine-protein kinase PS... | 135 | 0.000000000007 | 73.9 | 33 | 53 | GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0060917; P:regulation of (1->6)-beta-D-glucan biosynthetic process; IGI:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 209 | Q54JG7 | 485 | DST4_DICDI Serine/threonine-protein kinase ds... | 154 | 0.000000000007 | 73.2 | 31 | 53 | GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase. | 210 | Q5R495 | 527 | OXSR1_PONAB Serine/threonine-protein kinase O... | 189 | 0.000000000007 | 73.2 | 29 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB. | 211 | O60307 | 1309 | MAST3_HUMAN Microtubule-associated serine/thr... | 245 | 0.000000000007 | 73.9 | 26 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | |