rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | Q7Q732 | 317 | DHRS7_ANOGA Dehydrogenase/reductase SDR famil... | 204 | 0.000000002 | 61.6 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 152 | P14697 | 246 | PHBB_CUPNH Acetoacetyl-CoA reductase OS=(Rals... | 173 | 0.000000003 | 60.5 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:UniProtKB-KW. | 153 | P0AG84 | 294 | YGHA_ECOLI Uncharacterized oxidoreductase ygh... | 176 | 0.000000003 | 60.8 | 27 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 154 | P0AG85 | 294 | YGHA_ECO57 Uncharacterized oxidoreductase ygh... | 176 | 0.000000003 | 60.8 | 27 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 155 | Q05528 | 253 | KDUD_DICD3 2-dehydro-3-deoxy-D-gluconate 5-de... | 212 | 0.000000003 | 60.5 | 22 | 49 | | | | | | | | | | | GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 156 | P0AET8 | 255 | HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogena... | 159 | 0.000000003 | 60.5 | 28 | 47 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0008709; F:cholate 7-alpha-dehydrogenase activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 157 | P0AET9 | 255 | HDHA_ECO57 7-alpha-hydroxysteroid dehydrogena... | 159 | 0.000000003 | 60.5 | 28 | 47 | | | | | | | | | | | GO:0008709; F:cholate 7-alpha-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 158 | Q3T046 | 245 | BDH2_BOVIN 3-hydroxybutyrate dehydrogenase ty... | 186 | 0.000000003 | 60.1 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB. | | | | | | | | | | GO:0042168; P:heme metabolic process; ISS:UniProtKB.::GO:0055072; P:iron ion homeostasis; ISS:UniProtKB.::GO:0019290; P:siderophore biosynthetic process; ISS:UniProtKB. | 159 | Q92GE0 | 241 | FABG_RICCN 3-oxoacyl-[acyl-carrier-protein] r... | 172 | 0.000000003 | 60.1 | 27 | 48 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 160 | A8N6B4 | 339 | MKAR_COPC7 3-ketoacyl-CoA reductase OS=9003) ... | 169 | 0.000000004 | 60.8 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 161 | Q28IU1 | 320 | DHB12_XENTR Estradiol 17-beta-dehydrogenase 1... | 183 | 0.000000004 | 60.8 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 162 | Q4R5G7 | 312 | DHB12_MACFA Estradiol 17-beta-dehydrogenase 1... | 170 | 0.000000004 | 60.5 | 28 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 163 | P52037 | 247 | YGFF_ECOLI Uncharacterized oxidoreductase ygf... | 195 | 0.000000004 | 59.7 | 30 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 164 | Q8MJY8 | 266 | PGDH_MACFA 15-hydroxyprostaglandin dehydrogen... | 203 | 0.000000005 | 60.1 | 25 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; IEP:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 165 | Q01198 | 305 | LIGD_PSEPA C alpha-dehydrogenase OS=Pseudomon... | 168 | 0.000000005 | 60.5 | 31 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046274; P:lignin catabolic process; IEA:UniProtKB-KW. | 166 | P15428 | 266 | PGDH_HUMAN 15-hydroxyprostaglandin dehydrogen... | 199 | 0.000000005 | 59.7 | 25 | 45 | GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; IDA:UniProtKB.::GO:0019372; P:lipoxygenase pathway; TAS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 167 | Q56841 | 249 | HCDS_XANP2 2-(S)-hydroxypropyl-CoM dehydrogen... | 228 | 0.000000006 | 59.7 | 32 | 43 | | | | | | | | | | | GO:0050575; F:2-(S)-hydroxypropyl-CoM dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 168 | Q92506 | 261 | DHB8_HUMAN Estradiol 17-beta-dehydrogenase 8 ... | 244 | 0.000000008 | 59.3 | 25 | 43 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IDA:UniProtKB.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IDA:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 169 | Q3T0C2 | 266 | PGDH_BOVIN 15-hydroxyprostaglandin dehydrogen... | 232 | 0.000000008 | 59.3 | 23 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0060206; P:estrous cycle phase; IEP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 170 | Q48436 | 256 | BUDC_KLEPN Diacetyl reductase [(S)-acetoin fo... | 157 | 0.000000009 | 58.9 | 26 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 171 | O16925 | 314 | STDH4_CAEEL Putative steroid dehydrogenase 4 ... | 172 | 0.00000001 | 59.3 | 31 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 172 | P87218 | 280 | SOU2_CANAL Sorbose reductase homolog SOU2 OS=... | 205 | 0.00000001 | 59.3 | 28 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 173 | O07399 | 255 | FABG_MYCAV 3-oxoacyl-[acyl-carrier-protein] r... | 184 | 0.00000001 | 58.9 | 26 | 47 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 174 | P43066 | 281 | ARDH_CANAW D-arabinitol 2-dehydrogenase [ribu... | 210 | 0.00000001 | 58.9 | 25 | 44 | | | | | | | | | | | GO:0047038; F:D-arabinitol 2-dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; ISS:UniProtKB. | 175 | Q8VCC1 | 269 | PGDH_MOUSE 15-hydroxyprostaglandin dehydrogen... | 262 | 0.00000001 | 58.9 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; IMP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 176 | Q06136 | 332 | KDSR_HUMAN 3-ketodihydrosphingosine reductase... | 255 | 0.00000001 | 59.3 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; IDA:MGI.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome. | 177 | Q05016 | 267 | YM71_YEAST Uncharacterized oxidoreductase YMR... | 211 | 0.00000001 | 58.5 | 27 | 43 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IDA:SGD. | | | | | | | | | | | 178 | B2WMJ3 | 341 | MKAR_PYRTR 3-ketoacyl-CoA reductase OS=fungus... | 201 | 0.00000001 | 59.3 | 25 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 179 | P47227 | 277 | BPHB_BURXL Cis-2,3-dihydrobiphenyl-2,3-diol d... | 188 | 0.00000001 | 58.5 | 32 | 44 | | | | | | | | | | | GO:0018509; F:cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 180 | Q4UK62 | 241 | FABG_RICFE 3-oxoacyl-[acyl-carrier-protein] r... | 169 | 0.00000002 | 58.2 | 24 | 49 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 181 | O07575 | 289 | YHDF_BACSU Uncharacterized oxidoreductase yhd... | 177 | 0.00000002 | 58.5 | 27 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |