| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P78325 | 824 | ADAM8_HUMAN Disintegrin and metalloproteinase... | 51 | 0.89 | 32.7 | 33 | 49 | GO:0071133; C:alpha9-beta1 integrin-ADAM8 complex; ISS:BHF-UCL.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0032127; C:dense core granule membrane; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL.::GO:0032010; C:phagolysosome; IDA:BHF-UCL.::GO:0002102; C:podosome; IDA:BHF-UCL.::GO:0042581; C:specific granule; IDA:BHF-UCL.::GO:0070820; C:tertiary granule; IDA:BHF-UCL. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:BHF-UCL.::GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0043621; F:protein self-association; TAS:BHF-UCL.::GO:0008270; F:zinc ion binding; TAS:BHF-UCL. | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; ISS:BHF-UCL.::GO:0001525; P:angiogenesis; ISS:BHF-UCL.::GO:0000902; P:cell morphogenesis; ISS:BHF-UCL.::GO:0071456; P:cellular response to hypoxia; IDA:BHF-UCL.::GO:0002523; P:leukocyte migration involved in inflammatory response; ISS:BHF-UCL.::GO:0048247; P:lymphocyte chemotaxis; ISS:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.::GO:0002675; P:positive regulation of acute inflammatory response; ISS:BHF-UCL.::GO:0045780; P:positive regulation of bone resorption; ISS:BHF-UCL.::GO:0045785; P:positive regulation of cell adhesion; ISS:BHF-UCL.::GO:2000418; P:positive regulation of eosinophil migration; ISS:BHF-UCL.::GO:2000415; P:positive regulation of fibronectin-dependent thymocyte migration; ISS:BHF-UCL.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:2000391; P:positive regulation of neutrophil extravasation; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:BHF-UCL.::GO:0010954; P:positive regulation of protein processing; NAS:BHF-UCL.::GO:0050714; P:positive regulation of protein secretion; IC:BHF-UCL.::GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:BHF-UCL.::GO:0070245; P:positive regulation of thymocyte apoptotic process; ISS:BHF-UCL.::GO:2000309; P:positive regulation of tumor necrosis factor (ligand) superfamily member 11 production; ISS:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0022407; P:regulation of cell-cell adhesion; IDA:BHF-UCL. | 2 | Q8N436 | 756 | CPXM2_HUMAN Inactive carboxypeptidase-like pr... | 60 | 1.6 | 32 | 27 | 45 | GO:0005615; C:extracellular space; IDA:BHF-UCL. | | | | | | | | | | GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:InterPro. | 3 | Q0HJN6 | 676 | SYM_SHESM Methionine--tRNA ligase OS=Shewanel... | 33 | 2.3 | 31.6 | 36 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro. | 4 | B6HP56 | 458 | LIS11_PENCW Nuclear distribution protein nudF... | 93 | 3.1 | 31.2 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 5 | Q8EDX2 | 676 | SYM_SHEON Methionine--tRNA ligase OS=Shewanel... | 33 | 3.2 | 31.2 | 36 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro. | 6 | Q9V1H9 | 332 | AROB_PYRAB 3-dehydroquinate synthase OS=Pyroc... | 73 | 3.3 | 31.2 | 36 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003856; F:3-dehydroquinate synthase activity; IEA:HAMAP. | | | | | | | | | | GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:HAMAP. | 7 | O00468 | 2045 | AGRIN_HUMAN Agrin OS=Homo sapiens (Human). GN... | 46 | 3.8 | 31.2 | 37 | 50 | GO:0005605; C:basal lamina; IDA:UniProtKB. | | | | | | | | | | GO:0043236; F:laminin binding; TAS:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045162; P:clustering of voltage-gated sodium channels; TAS:UniProtKB.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; TAS:UniProtKB.::GO:0043113; P:receptor clustering; IDA:UniProtKB. | 8 | P97436 | 237 | NKX31_MOUSE Homeobox protein Nkx-3.1 OS=Mus m... | 43 | 4.3 | 30.4 | 37 | 53 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0004882; F:androgen receptor activity; ISS:UniProtKB.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0030284; F:estrogen receptor activity; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0097162; F:MADS box domain binding; IDA:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; ISS:UniProtKB.::GO:0030295; F:protein kinase activator activity; ISS:UniProtKB.::GO:0043621; F:protein self-association; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0008633; P:activation of pro-apoptotic gene products; ISS:UniProtKB.::GO:0060442; P:branching involved in prostate gland morphogenesis; IMP:MGI.::GO:0048754; P:branching morphogenesis of a tube; IMP:MGI.::GO:0035907; P:dorsal aorta development; IEP:UniProtKB.::GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IMP:MGI.::GO:0007507; P:heart development; IEP:BHF-UCL.::GO:0035260; P:internal genitalia morphogenesis; TAS:BHF-UCL.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0001656; P:metanephros development; IEP:UniProtKB.::GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; IMP:MGI.::GO:0071899; P:negative regulation of estrogen receptor binding; ISS:UniProtKB.::GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IDA:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0060037; P:pharyngeal system development; IEP:BHF-UCL.::GO:2000836; P:positive regulation of androgen secretion; ISS:UniProtKB.::GO:0051781; P:positive regulation of cell division; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:2000500; P:positive regulation of induction of apoptosis in response to chemical stimulus; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0033574; P:response to testosterone stimulus; IMP:UniProtKB.::GO:0001756; P:somitogenesis; IEP:BHF-UCL. | 9 | O44712 | 602 | AHR_CAEEL Aryl hydrocarbon receptor protein 1... | 26 | 5.4 | 30.4 | 50 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:WormBase.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:WormBase.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007610; P:behavior; IEA:UniProtKB-KW.::GO:0030522; P:intracellular receptor mediated signaling pathway; TAS:WormBase.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009410; P:response to xenobiotic stimulus; IDA:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | P36616 | 544 | DSK1_SCHPO Protein kinase dsk1 OS=Schizosacch... | 74 | 5.9 | 30.4 | 30 | 46 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; NAS:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.::GO:0048024; P:regulation of nuclear mRNA splicing, via spliceosome; IGI:PomBase. | 11 | P21263 | 1893 | NEST_RAT Nestin OS=Rattus norvegicus (Rat). G... | 57 | 8.9 | 30 | 33 | 44 | GO:0005882; C:intermediate filament; IDA:RGD. | | | | | | | | | | GO:0031730; F:CCR5 chemokine receptor binding; IPI:RGD.::GO:0019215; F:intermediate filament binding; ISS:UniProtKB.::GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0007420; P:brain development; ISS:UniProtKB.::GO:0031076; P:embryonic camera-type eye development; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; NAS:RGD.::GO:0030844; P:positive regulation of intermediate filament depolymerization; IDA:UniProtKB.::GO:2000179; P:positive regulation of neural precursor cell proliferation; IMP:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010212; P:response to ionizing radiation; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD. |
