| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O60103 | 1242 | DOA10_SCHPO ERAD-associated E3 ubiquitin-prot... | 189 | 0.042 | 42.4 | 24 | 41 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:PomBase. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase. | 2 | Q5R9W1 | 910 | MARH6_PONAB E3 ubiquitin-protein ligase MARCH... | 289 | 0.00000002 | 63.2 | 23 | 43 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB. | 3 | Q6ZQ89 | 909 | MARH6_MOUSE E3 ubiquitin-protein ligase MARCH... | 289 | 0.000000007 | 64.7 | 23 | 43 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB. | 4 | O60337 | 910 | MARH6_HUMAN E3 ubiquitin-protein ligase MARCH... | 289 | 0.00000002 | 62.8 | 23 | 43 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB. | | | | | | | | | | GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB. | 5 | P40318 | 1319 | DOA10_YEAST ERAD-associated E3 ubiquitin-prot... | 144 | 1e-18 | 96.7 | 33 | 51 | GO:0000837; C:Doa10p ubiquitin ligase complex; IDA:SGD.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0005637; C:nuclear inner membrane; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; IMP:SGD. | 6 | Q9DBD2 | 286 | MARH8_MOUSE E3 ubiquitin-protein ligase MARCH... | 83 | 0.00000000000005 | 78.2 | 46 | 55 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042289; F:MHC class II protein binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IDA:UniProtKB.::GO:0045347; P:negative regulation of MHC class II biosynthetic process; IDA:BHF-UCL. | 7 | Q0VD59 | 289 | MARH8_BOVIN E3 ubiquitin-protein ligase MARCH... | 62 | 0.0000000000001 | 77 | 53 | 63 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 8 | Q28IK8 | 264 | MARH8_XENTR E3 ubiquitin-protein ligase MARCH... | 62 | 0.0000000000003 | 75.5 | 53 | 61 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 9 | Q5XH39 | 264 | MARH8_XENLA E3 ubiquitin-protein ligase MARCH... | 62 | 0.0000000000003 | 75.5 | 53 | 61 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 10 | Q5T0T0 | 291 | MARH8_HUMAN E3 ubiquitin-protein ligase MARCH... | 63 | 0.0000000000004 | 75.5 | 51 | 62 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 11 | Q6NZQ8 | 289 | MARH1_MOUSE E3 ubiquitin-protein ligase MARCH... | 53 | 0.000000000001 | 73.9 | 55 | 68 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042287; F:MHC protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IMP:UniProtKB.::GO:0006955; P:immune response; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 12 | Q8TCQ1 | 289 | MARH1_HUMAN E3 ubiquitin-protein ligase MARCH... | 53 | 0.000000000001 | 73.9 | 55 | 68 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042287; F:MHC protein binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IDA:UniProtKB.::GO:0006955; P:immune response; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 13 | Q32L65 | 245 | MARH2_BOVIN E3 ubiquitin-protein ligase MARCH... | 55 | 0.0000000002 | 66.6 | 53 | 60 | GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 14 | Q5I0I2 | 246 | MARH2_RAT E3 ubiquitin-protein ligase MARCH2 ... | 69 | 0.0000000002 | 66.6 | 43 | 54 | GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 15 | Q0IH10 | 252 | MARH3_XENLA E3 ubiquitin-protein ligase MARCH... | 72 | 0.0000000003 | 65.9 | 43 | 60 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 16 | Q5PQ35 | 246 | MARH2_XENLA E3 ubiquitin-protein ligase MARCH... | 51 | 0.0000000004 | 65.9 | 53 | 65 | GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 17 | Q28EX7 | 246 | MARH2_XENTR E3 ubiquitin-protein ligase MARCH... | 51 | 0.0000000004 | 65.5 | 53 | 65 | GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 18 | Q9P0N8 | 246 | MARH2_HUMAN E3 ubiquitin-protein ligase MARCH... | 59 | 0.0000000008 | 64.7 | 49 | 58 | GO:0031410; C:cytoplasmic vesicle; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 19 | Q68FA7 | 251 | MARH3_XENTR E3 ubiquitin-protein ligase MARCH... | 67 | 0.000000002 | 63.5 | 43 | 61 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 20 | Q86UD3 | 253 | MARH3_HUMAN E3 ubiquitin-protein ligase MARCH... | 53 | 0.000000006 | 62.4 | 51 | 66 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IDA:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 21 | Q99M02 | 246 | MARH2_MOUSE E3 ubiquitin-protein ligase MARCH... | 65 | 0.000000006 | 62 | 45 | 55 | GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 22 | Q8BRX9 | 218 | MARH3_MOUSE E3 ubiquitin-protein ligase MARCH... | 53 | 0.000000006 | 61.6 | 51 | 66 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 23 | Q5XIE5 | 253 | MARH3_RAT E3 ubiquitin-protein ligase MARCH3 ... | 53 | 0.000000006 | 62 | 51 | 66 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 24 | A0JN69 | 253 | MARH3_BOVIN E3 ubiquitin-protein ligase MARCH... | 53 | 0.000000006 | 62 | 51 | 66 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 25 | Q8CBH7 | 400 | MARHB_MOUSE E3 ubiquitin-protein ligase MARCH... | 110 | 0.000000007 | 63.5 | 29 | 54 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 26 | A6P320 | 398 | MARHB_RAT E3 ubiquitin-protein ligase MARCH11... | 110 | 0.000000007 | 63.5 | 29 | 54 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 27 | Q1LVZ2 | 249 | MARH2_DANRE E3 ubiquitin-protein ligase MARCH... | 62 | 0.000000008 | 61.6 | 45 | 56 | GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 28 | A6NNE9 | 402 | MARHB_HUMAN E3 ubiquitin-protein ligase MARCH... | 110 | 0.00000002 | 62 | 28 | 53 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 29 | P27426 | 285 | VIE1_BHV4D Probable E3 ubiquitin-protein liga... | 67 | 0.00000008 | 59.3 | 39 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | Q0P496 | 421 | MARH4_DANRE E3 ubiquitin-protein ligase MARCH... | 128 | 0.0000002 | 58.9 | 30 | 49 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 31 | Q80TE3 | 409 | MARH4_MOUSE E3 ubiquitin-protein ligase MARCH... | 108 | 0.0000003 | 58.5 | 32 | 50 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |
