rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q9HES8 | 1192 | PYC_ASPNG Pyruvate carboxylase OS=Aspergillus... | 144 | 0.11 | 41.6 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 62 | Q0CLK1 | 1193 | PYC_ASPTN Pyruvate carboxylase OS=Aspergillus... | 99 | 0.54 | 39.3 | 25 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 63 | O93918 | 1193 | PYC_ASPTE Pyruvate carboxylase OS=Aspergillus... | 144 | 0.59 | 39.3 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 64 | P46392 | 598 | BCCA_MYCLE Acetyl-/propionyl-coenzyme A carbo... | 64 | 1.7 | 37.4 | 33 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 65 | Q9UUE1 | 1185 | PYC_SCHPO Pyruvate carboxylase OS=Schizosacch... | 514 | 2e-45 | 184 | 29 | 45 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; ISS:PomBase. | | | | | | | | | | GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0006094; P:gluconeogenesis; ISS:PomBase. | 66 | P38095 | 1241 | LAMA_EMENI Putative urea carboxylase OS=194 /... | 522 | 4e-45 | 183 | 27 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.::GO:0004847; F:urea carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 67 | P78992 | 1189 | PYC_PICPA Pyruvate carboxylase OS=Pichia past... | 515 | 5e-44 | 180 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 68 | Q4J8E8 | 1052 | CARB_SULAC Carbamoyl-phosphate synthase large... | 257 | 0.00000000006 | 72 | 24 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 69 | Q8U085 | 1056 | CARB_PYRFU Carbamoyl-phosphate synthase large... | 190 | 0.0000000002 | 70.5 | 25 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 70 | Q4L5Q5 | 1057 | CARB_STAHJ Carbamoyl-phosphate synthase large... | 177 | 5.3 | 35.8 | 17 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 71 | Q49WY4 | 1057 | CARB_STAS1 Carbamoyl-phosphate synthase large... | 195 | 2.5 | 37 | 17 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 72 | Q970U7 | 1049 | CARB_SULTO Carbamoyl-phosphate synthase large... | 257 | 0.000000004 | 66.2 | 23 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 73 | Q8T2J9 | 588 | MCCB_DICDI Methylcrotonoyl-CoA carboxylase be... | 351 | 0.000000007 | 64.7 | 25 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC. | | | | | | | | | | | 74 | P27708 | 2225 | PYR1_HUMAN CAD protein OS=Homo sapiens (Human... | 199 | 0.00000001 | 64.3 | 23 | 45 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; ISS:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0043195; C:terminal button; ISS:BHF-UCL. | | | | | | | | | | GO:0070335; F:aspartate binding; ISS:BHF-UCL.::GO:0004070; F:aspartate carbamoyltransferase activity; ISS:BHF-UCL.::GO:0005524; F:ATP binding; ISS:BHF-UCL.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; ISS:BHF-UCL.::GO:0004151; F:dihydroorotase activity; ISS:BHF-UCL.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0042802; F:identical protein binding; ISS:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; ISS:BHF-UCL. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; ISS:BHF-UCL.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0017144; P:drug metabolic process; ISS:BHF-UCL.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:BHF-UCL.::GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 75 | P07259 | 2214 | PYR1_YEAST Protein URA2 OS=Saccharomyces cere... | 174 | 0.024 | 43.9 | 24 | 40 | GO:0016021; C:integral to membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IDA:SGD.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0045984; P:negative regulation of pyrimidine base metabolic process; IDA:SGD.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 76 | P08955 | 2225 | PYR1_MESAU CAD protein OS=Mesocricetus auratu... | 199 | 0.00000006 | 62.4 | 22 | 46 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL. | | | | | | | | | | GO:0070335; F:aspartate binding; IDA:BHF-UCL.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:BHF-UCL.::GO:0004151; F:dihydroorotase activity; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IDA:BHF-UCL.::GO:0002134; F:UTP binding; IDA:MGI. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IDA:BHF-UCL.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 77 | Q8CPJ4 | 1057 | CARB_STAES Carbamoyl-phosphate synthase large... | 191 | 2.5 | 37 | 16 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 78 | B9DPN2 | 1057 | CARB_STACT Carbamoyl-phosphate synthase large... | 194 | 1.9 | 37.4 | 16 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 79 | O31825 | 511 | YNGE_BACSU Uncharacterized carboxylase YngE O... | 51 | 0.29 | 40 | 39 | 61 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 80 | P58939 | 1113 | CARB_CORGL Carbamoyl-phosphate synthase large... | 193 | 0.052 | 42.7 | 19 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 81 | C4KHM7 | 1051 | CARB_SULIK Carbamoyl-phosphate synthase large... | 257 | 0.0000003 | 60.1 | 21 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 82 | C3MW21 | 1051 | CARB_SULIM Carbamoyl-phosphate synthase large... | 257 | 0.0000003 | 59.7 | 21 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 83 | C3N664 | 1051 | CARB_SULIA Carbamoyl-phosphate synthase large... | 257 | 0.0000003 | 59.7 | 21 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 84 | P05990 | 2224 | PYR1_DROME CAD protein OS=Drosophila melanoga... | 191 | 0.0000003 | 60.1 | 23 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:FlyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:FlyBase.::GO:0004151; F:dihydroorotase activity; IDA:FlyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IMP:FlyBase.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 85 | Q91437 | 2242 | PYR1_SQUAC CAD protein OS=Squalus acanthias (... | 182 | 0.0000003 | 59.7 | 23 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0004151; F:dihydroorotase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 86 | Q8TUT7 | 542 | CARB2_METKA Carbamoyl-phosphate synthase larg... | 201 | 0.0000004 | 58.9 | 24 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 87 | C3NEM0 | 1051 | CARB_SULIY Carbamoyl-phosphate synthase large... | 257 | 0.0000004 | 59.3 | 21 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 88 | C3MQE3 | 1051 | CARB_SULIL Carbamoyl-phosphate synthase large... | 257 | 0.0000004 | 59.3 | 21 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 89 | Q5HPY8 | 1057 | CARB_STAEQ Carbamoyl-phosphate synthase large... | 194 | 2.3 | 37.4 | 16 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 90 | Q99MN9 | 541 | PCCB_MOUSE Propionyl-CoA carboxylase beta cha... | 309 | 0.0000005 | 58.5 | 22 | 39 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004658; F:propionyl-CoA carboxylase activity; IEA:EC. | | | | | | | | | | | 91 | Q8FT42 | 1113 | CARB_COREF Carbamoyl-phosphate synthase large... | 204 | 4.9 | 36.2 | 17 | 37 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. |