rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q24742 | 3828 | TRX_DROVI Histone-lysine N-methyltransferase ... | 78 | 3.1 | 34.3 | 28 | 49 | GO:0035097; C:histone methyltransferase complex; IEA:InterPro. | | | | | | | | | | GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 92 | Q3UG20 | 1868 | MLL5_MOUSE Histone-lysine N-methyltransferase... | 82 | 3.2 | 34.3 | 28 | 49 | GO:0070688; C:MLL5-L complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042800; F:histone methyltransferase activity (H3-K4 specific); ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; ISS:BHF-UCL.::GO:0006306; P:DNA methylation; IMP:UniProtKB.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0042119; P:neutrophil activation; IMP:UniProtKB.::GO:0002446; P:neutrophil mediated immunity; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0048384; P:retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 93 | Q8IRW8 | 2431 | TRR_DROME Histone-lysine N-methyltransferase ... | 71 | 3.3 | 34.3 | 30 | 46 | GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005700; C:polytene chromosome; IDA:FlyBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:FlyBase.::GO:0005102; F:receptor binding; IPI:FlyBase.::GO:0003713; F:transcription coactivator activity; IGI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:FlyBase.::GO:0007458; P:progression of morphogenetic furrow involved in compound eye morphogenesis; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 94 | Q9C0A6 | 1442 | SETD5_HUMAN SET domain-containing protein 5 O... | 80 | 3.4 | 33.9 | 28 | 46 | | | | | | | | | | | | | | | | | | | | | | 95 | Q6DGD3 | 411 | SV91A_DANRE Histone-lysine N-methyltransferas... | 50 | 3.4 | 33.5 | 36 | 56 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0031017; P:exocrine pancreas development; IMP:ZFIN.::GO:0051567; P:histone H3-K9 methylation; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0060042; P:retina morphogenesis in camera-type eye; IMP:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 96 | Q9M1X9 | 352 | ASHH4_ARATH Putative histone-lysine N-methylt... | 53 | 3.5 | 33.5 | 34 | 55 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | | 97 | Q5XJV7 | 1441 | SETD5_MOUSE SET domain-containing protein 5 O... | 80 | 3.8 | 33.9 | 28 | 46 | | | | | | | | | | | | | | | | | | | | | | 98 | P55200 | 3966 | MLL1_MOUSE Histone-lysine N-methyltransferase... | 48 | 5.5 | 33.5 | 33 | 56 | GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); ISS:UniProtKB.::GO:0045322; F:unmethylated CpG binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0006306; P:DNA methylation; IMP:MGI.::GO:0035162; P:embryonic hemopoiesis; IMP:MGI.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 99 | Q28CQ7 | 406 | SUV92_XENTR Histone-lysine N-methyltransferas... | 50 | 5.7 | 33.1 | 34 | 56 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 100 | Q03164 | 3969 | MLL1_HUMAN Histone-lysine N-methyltransferase... | 48 | 5.8 | 33.5 | 33 | 56 | GO:0071339; C:MLL1 complex; IDA:UniProtKB. | | | | | | | | | | GO:0003680; F:AT DNA binding; NAS:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; IDA:UniProtKB.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0045322; F:unmethylated CpG binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035162; P:embryonic hemopoiesis; TAS:UniProtKB.::GO:0080182; P:histone H3-K4 trimethylation; IDA:BHF-UCL.::GO:0043984; P:histone H4-K16 acetylation; IMP:UniProtKB.::GO:2001040; P:positive regulation of cellular response to drug; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0032411; P:positive regulation of transporter activity; IMP:BHF-UCL.::GO:0006461; P:protein complex assembly; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 101 | Q8NEZ4 | 4911 | MLL3_HUMAN Histone-lysine N-methyltransferase... | 58 | 6.4 | 33.1 | 34 | 57 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 102 | Q9Y7R4 | 920 | SET1_SCHPO Histone-lysine N-methyltransferase... | 48 | 6.5 | 33.1 | 35 | 56 | GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0000790; C:nuclear chromatin; NAS:PomBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:PomBase. | | | | | | | | | | GO:0042800; F:histone methyltransferase activity (H3-K4 specific); TAS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0000077; P:DNA damage checkpoint; IGI:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000723; P:telomere maintenance; IMP:PomBase. | 103 | P0CO26 | 1469 | SET1_CRYNJ Histone-lysine N-methyltransferase... | 53 | 6.9 | 33.1 | 34 | 57 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 104 | P0CO27 | 1469 | SET1_CRYNB Histone-lysine N-methyltransferase... | 53 | 6.9 | 33.1 | 34 | 57 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 105 | Q8IZD2 | 1858 | MLL5_HUMAN Histone-lysine N-methyltransferase... | 82 | 7.4 | 33.1 | 29 | 50 | GO:0070688; C:MLL5-L complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; IDA:BHF-UCL.::GO:0006306; P:DNA methylation; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0042119; P:neutrophil activation; ISS:UniProtKB.::GO:0002446; P:neutrophil mediated immunity; ISS:UniProtKB.::GO:0030854; P:positive regulation of granulocyte differentiation; IMP:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0048384; P:retinoic acid receptor signaling pathway; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 106 | Q4WNH8 | 1241 | SET1_ASPFU Histone-lysine N-methyltransferase... | 48 | 7.6 | 32.7 | 33 | 58 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 107 | P20659 | 3726 | TRX_DROME Histone-lysine N-methyltransferase ... | 78 | 9.1 | 32.7 | 27 | 47 | GO:0035097; C:histone methyltransferase complex; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0008023; C:transcription elongation factor complex; IPI:FlyBase. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:FlyBase.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0008157; F:protein phosphatase 1 binding; IPI:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0008354; P:germ cell migration; IMP:FlyBase.::GO:0043966; P:histone H3 acetylation; IMP:FlyBase.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |