| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q01112 | 192 | CDC42_SCHPO Cell division control protein 42 ... | 190 | 5e-118 | 340 | 86 | 93 | GO:0071521; C:Cdc42 GTPase complex; NAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0009898; C:internal side of plasma membrane; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032488; P:Cdc42 protein signal transduction; IC:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0032955; P:regulation of barrier septum assembly; IMP:PomBase.::GO:0032951; P:regulation of beta-glucan biosynthetic process; IGI:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase. | 2 | P19073 | 191 | CDC42_YEAST Cell division control protein 42 ... | 189 | 4e-111 | 322 | 80 | 89 | GO:0005935; C:cellular bud neck; TAS:SGD.::GO:0005934; C:cellular bud tip; TAS:SGD.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.::GO:0005625; C:soluble fraction; IDA:SGD. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; TAS:SGD. | | | | | | | | | | GO:0007118; P:budding cell apical bud growth; IMP:SGD.::GO:0007119; P:budding cell isotropic bud growth; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IGI:SGD.::GO:0045921; P:positive regulation of exocytosis; IPI:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.::GO:0031384; P:regulation of initiation of mating projection growth; IMP:SGD.::GO:0032889; P:regulation of vacuole fusion, non-autophagic; IMP:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD. | 3 | C4YDI6 | 191 | CDC42_CANAW Cell division control protein 42 ... | 189 | 4e-110 | 319 | 80 | 90 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 4 | P0CY33 | 191 | CDC42_CANAL Cell division control protein 42 ... | 189 | 4e-110 | 319 | 80 | 90 | GO:0030428; C:cell septum; NAS:CGD.::GO:0005935; C:cellular bud neck; IDA:CGD.::GO:0005934; C:cellular bud tip; IDA:CGD.::GO:0031562; C:hyphal tip polarisome; IDA:CGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031521; C:spitzenkorper; IDA:CGD. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:CGD. | | | | | | | | | | GO:0007114; P:cell budding; IMP:CGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000920; P:cytokinetic cell separation; IMP:CGD.::GO:0030010; P:establishment of cell polarity; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0001558; P:regulation of cell growth; IMP:CGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 5 | Q9HF56 | 191 | CDC42_ASHGO Cell division control protein 42 ... | 191 | 6e-110 | 319 | 80 | 89 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 6 | Q8CFN2 | 191 | CDC42_RAT Cell division control protein 42 ho... | 191 | 3e-106 | 310 | 78 | 86 | GO:0000139; C:Golgi membrane; IDA:BHF-UCL.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0030141; C:secretory granule; IDA:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; TAS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:RGD.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:RGD. | | | | | | | | | | GO:0090135; P:actin filament branching; IMP:RGD.::GO:0030010; P:establishment of cell polarity; TAS:RGD.::GO:0051683; P:establishment of Golgi localization; IMP:BHF-UCL.::GO:0007030; P:Golgi organization; IMP:BHF-UCL.::GO:0072384; P:organelle transport along microtubule; IMP:BHF-UCL.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0090316; P:positive regulation of intracellular protein transport; IMP:RGD.::GO:0046330; P:positive regulation of JNK cascade; IDA:RGD.::GO:0048554; P:positive regulation of metalloenzyme activity; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0051835; P:positive regulation of synapse structural plasticity; IMP:RGD.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0017157; P:regulation of exocytosis; TAS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; TAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0002040; P:sprouting angiogenesis; IMP:RGD.::GO:0060661; P:submandibular salivary gland formation; IEP:RGD. | 7 | Q007T2 | 191 | CDC42_PIG Cell division control protein 42 ho... | 191 | 3e-106 | 310 | 78 | 86 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 8 | P60766 | 191 | CDC42_MOUSE Cell division control protein 42 ... | 191 | 3e-106 | 310 | 78 | 86 | GO:0045177; C:apical part of cell; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:MGI.::GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.::GO:0003924; F:GTPase activity; IDA:MGI. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IMP:MGI.::GO:0034332; P:adherens junction organization; IMP:MGI.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:MGI.::GO:0034613; P:cellular protein localization; IMP:MGI.::GO:0016197; P:endosome transport; TAS:UniProtKB.::GO:0090136; P:epithelial cell-cell adhesion; IMP:MGI.::GO:0060684; P:epithelial-mesenchymal cell signaling; IMP:MGI.::GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IMP:MGI.::GO:0046847; P:filopodium assembly; IDA:MGI.::GO:0031069; P:hair follicle morphogenesis; IMP:MGI.::GO:0060789; P:hair follicle placode formation; IMP:MGI.::GO:0031424; P:keratinization; IMP:MGI.::GO:0003334; P:keratinocyte development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0010629; P:negative regulation of gene expression; IMP:MGI.::GO:0048664; P:neuron fate determination; IMP:MGI.::GO:0007097; P:nuclear migration; IMP:MGI.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0010628; P:positive regulation of gene expression; IMP:MGI.::GO:0071338; P:positive regulation of hair follicle cell proliferation; IMP:MGI.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:MGI.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007088; P:regulation of mitosis; IMP:MGI.::GO:0042176; P:regulation of protein catabolic process; IMP:MGI.::GO:0043497; P:regulation of protein heterodimerization activity; IDA:MGI.::GO:0045859; P:regulation of protein kinase activity; IMP:MGI.::GO:0031647; P:regulation of protein stability; IMP:MGI.::GO:0007266; P:Rho protein signal transduction; TAS:MGI. | 9 | P60953 | 191 | CDC42_HUMAN Cell division control protein 42 ... | 191 | 3e-106 | 310 | 78 | 86 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:BHF-UCL.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0072686; C:mitotic spindle; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0051233; C:spindle midzone; IDA:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0019901; F:protein kinase binding; IDA:BHF-UCL.::GO:0031996; F:thioesterase binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0051683; P:establishment of Golgi localization; ISS:BHF-UCL.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:BHF-UCL.::GO:0030225; P:macrophage differentiation; TAS:UniProtKB.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0031333; P:negative regulation of protein complex assembly; IPI:UniProtKB.::GO:0072384; P:organelle transport along microtubule; ISS:BHF-UCL.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IMP:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0031274; P:positive regulation of pseudopodium assembly; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 10 | P60952 | 191 | CDC42_CANFA Cell division control protein 42 ... | 191 | 3e-106 | 310 | 78 | 86 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 11 | Q2KJ93 | 191 | CDC42_BOVIN Cell division control protein 42 ... | 191 | 3e-106 | 310 | 78 | 86 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 12 | Q05062 | 191 | CDC42_CAEEL Cell division control protein 42 ... | 191 | 3e-106 | 310 | 79 | 86 | GO:0005938; C:cell cortex; IDA:WormBase.::GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005813; C:centrosome; IDA:WormBase.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:WormBase.::GO:0005886; C:plasma membrane; IDA:WormBase.::GO:0055037; C:recycling endosome; IDA:WormBase. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0032970; P:regulation of actin filament-based process; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 13 | Q90694 | 191 | CDC42_CHICK Cell division control protein 42 ... | 191 | 4e-106 | 309 | 78 | 86 | GO:0005912; C:adherens junction; ISS:AgBase.::GO:0005737; C:cytoplasm; ISS:AgBase.::GO:0030175; C:filopodium; ISS:AgBase.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:AgBase.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:AgBase. | | | | | | | | | | GO:0046847; P:filopodium assembly; ISS:AgBase.::GO:0045185; P:maintenance of protein location; ISS:AgBase.::GO:0031333; P:negative regulation of protein complex assembly; ISS:AgBase.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:AgBase.::GO:0045860; P:positive regulation of protein kinase activity; ISS:AgBase.::GO:0031274; P:positive regulation of pseudopodium assembly; ISS:AgBase.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 14 | Q4R4R6 | 191 | CDC42_MACFA Cell division control protein 42 ... | 191 | 7e-106 | 309 | 77 | 86 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 15 | Q29HY3 | 191 | CDC42_DROPS Cdc42 homolog OS=Drosophila pseud... | 188 | 1e-105 | 308 | 80 | 87 | GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045185; P:maintenance of protein location; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 16 | P40793 | 191 | CDC42_DROME Cdc42 homolog OS=Drosophila melan... | 188 | 2e-105 | 308 | 80 | 87 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0030424; C:axon; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0030426; C:growth cone; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0016028; C:rhabdomere; IMP:FlyBase. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0030041; P:actin filament polymerization; IMP:FlyBase.::GO:0060446; P:branching involved in open tracheal system development; IMP:FlyBase.::GO:0030031; P:cell projection assembly; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0045200; P:establishment of neuroblast polarity; IMP:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0035318; P:imaginal disc-derived wing hair outgrowth; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030011; P:maintenance of cell polarity; IMP:FlyBase.::GO:0045185; P:maintenance of protein location; IMP:UniProtKB.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IGI:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; IDA:FlyBase.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0008582; P:regulation of synaptic growth at neuromuscular junction; IDA:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007396; P:suture of dorsal opening; TAS:FlyBase.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:FlyBase.::GO:0042060; P:wound healing; IMP:FlyBase. | 17 | Q16YG0 | 191 | CDC42_AEDAE Cdc42 homolog OS=Aedes aegypti (Y... | 188 | 2e-105 | 307 | 80 | 87 | GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045185; P:maintenance of protein location; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 18 | Q17031 | 191 | CDC42_ANOGA Cdc42 homolog OS=Anopheles gambia... | 188 | 3e-105 | 307 | 80 | 87 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 19 | O94103 | 190 | CDC42_COLGL Cell division control protein 42 ... | 194 | 1e-101 | 298 | 82 | 86 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 20 | Q03206 | 191 | RAC1_CAEEL Ras-related protein ced-10 OS=Caen... | 188 | 2e-92 | 275 | 69 | 80 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0031410; C:cytoplasmic vesicle; IDA:WormBase.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048846; P:axon extension involved in axon guidance; IGI:WormBase.::GO:0031103; P:axon regeneration; IMP:WormBase.::GO:0010171; P:body morphogenesis; IGI:WormBase.::GO:0033563; P:dorsal/ventral axon guidance; IGI:WormBase.::GO:0043652; P:engulfment of apoptotic cell; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0008045; P:motor axon guidance; IGI:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0001764; P:neuron migration; IGI:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0030334; P:regulation of cell migration; IDA:UniProtKB.::GO:0050764; P:regulation of phagocytosis; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IDA:UniProtKB. | 21 | Q6RUV5 | 192 | RAC1_RAT Ras-related C3 botulinum toxin subst... | 192 | 3e-92 | 274 | 68 | 79 | GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:RGD.::GO:0003924; F:GTPase activity; IDA:RGD.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0017137; F:Rab GTPase binding; IPI:RGD. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:RGD.::GO:0045453; P:bone resorption; IDA:RGD.::GO:0008283; P:cell proliferation; IMP:RGD.::GO:0002551; P:mast cell chemotaxis; IMP:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0016601; P:Rac protein signal transduction; TAS:RGD.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB. | 22 | P63001 | 192 | RAC1_MOUSE Ras-related C3 botulinum toxin sub... | 192 | 3e-92 | 274 | 68 | 79 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0019897; C:extrinsic to plasma membrane; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0001891; C:phagocytic cup; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:MGI.::GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.::GO:0003924; F:GTPase activity; IDA:MGI. | | | | | | | | | | GO:0048532; P:anatomical structure arrangement; IMP:MGI.::GO:0002093; P:auditory receptor cell morphogenesis; IMP:MGI.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0045216; P:cell-cell junction organization; IMP:MGI.::GO:0021799; P:cerebral cortex radially oriented cell migration; IMP:MGI.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0048813; P:dendrite morphogenesis; IGI:MGI.::GO:0071542; P:dopaminergic neuron differentiation; IGI:MGI.::GO:0021831; P:embryonic olfactory bulb interneuron precursor migration; IMP:MGI.::GO:0043652; P:engulfment of apoptotic cell; IDA:BHF-UCL.::GO:0003382; P:epithelial cell morphogenesis; IMP:MGI.::GO:0006972; P:hyperosmotic response; IDA:MGI.::GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:MGI.::GO:0030334; P:regulation of cell migration; IMP:MGI.::GO:0097178; P:ruffle assembly; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:MGI.::GO:0060071; P:Wnt receptor signaling pathway, planar cell polarity pathway; IGI:MGI. | 23 | P63000 | 192 | RAC1_HUMAN Ras-related C3 botulinum toxin sub... | 192 | 3e-92 | 274 | 68 | 79 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0031996; F:thioesterase binding; IPI:UniProtKB. | | | | | | | | | | GO:0030041; P:actin filament polymerization; TAS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0048870; P:cell motility; IDA:UniProtKB.::GO:0007160; P:cell-matrix adhesion; NAS:BHF-UCL.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0006954; P:inflammatory response; TAS:ProtInc.::GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.::GO:0051668; P:localization within membrane; IMP:BHF-UCL.::GO:0032707; P:negative regulation of interleukin-23 production; IDA:BHF-UCL.::GO:0048261; P:negative regulation of receptor-mediated endocytosis; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.::GO:0035025; P:positive regulation of Rho protein signal transduction; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.::GO:0060263; P:regulation of respiratory burst; IDA:BHF-UCL.::GO:0031529; P:ruffle organization; TAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 24 | P62999 | 192 | RAC1_CANFA Ras-related C3 botulinum toxin sub... | 192 | 3e-92 | 274 | 68 | 79 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:UniProtKB. | | | | | | | | | | GO:0048870; P:cell motility; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 25 | P62998 | 192 | RAC1_BOVIN Ras-related C3 botulinum toxin sub... | 192 | 3e-92 | 274 | 68 | 79 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030334; P:regulation of cell migration; ISS:UniProtKB. | 26 | P40792 | 192 | RAC1_DROME Ras-related protein Rac1 OS=Drosop... | 189 | 4e-92 | 274 | 68 | 79 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0016028; C:rhabdomere; IDA:FlyBase. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0034334; P:adherens junction maintenance; IMP:FlyBase.::GO:0048675; P:axon extension; IMP:FlyBase.::GO:0007413; P:axonal fasciculation; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0035212; P:cell competition in a multicellular organism; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; TAS:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0046664; P:dorsal closure, amnioserosa morphology change; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0042067; P:establishment of ommatidial planar polarity; NAS:FlyBase.::GO:0007390; P:germ-band shortening; IMP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007516; P:hemocyte development; IMP:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0035320; P:imaginal disc-derived wing hair site selection; IMP:FlyBase.::GO:0002433; P:immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; IDA:FlyBase.::GO:0007254; P:JNK cascade; IMP:FlyBase.::GO:0030032; P:lamellipodium assembly; IMP:FlyBase.::GO:0008078; P:mesodermal cell migration; IMP:FlyBase.::GO:0007017; P:microtubule-based process; NAS:FlyBase.::GO:0016335; P:morphogenesis of larval imaginal disc epithelium; TAS:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0048747; P:muscle fiber development; IMP:FlyBase.::GO:0007520; P:myoblast fusion; IMP:FlyBase.::GO:0051450; P:myoblast proliferation; IMP:FlyBase.::GO:0010593; P:negative regulation of lamellipodium assembly; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0051963; P:regulation of synapse assembly; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0042052; P:rhabdomere development; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007426; P:tracheal outgrowth, open tracheal system; IGI:FlyBase.::GO:0007419; P:ventral cord development; IMP:FlyBase. | 27 | P48554 | 192 | RAC2_DROME Ras-related protein Rac2 OS=Drosop... | 189 | 1e-90 | 270 | 68 | 79 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0034334; P:adherens junction maintenance; IGI:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0035010; P:encapsulation of foreign target; IMP:FlyBase.::GO:0007390; P:germ-band shortening; IMP:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0002433; P:immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; IDA:FlyBase.::GO:0007254; P:JNK cascade; IMP:FlyBase.::GO:0030032; P:lamellipodium assembly; IMP:FlyBase.::GO:0007520; P:myoblast fusion; TAS:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IGI:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007426; P:tracheal outgrowth, open tracheal system; IGI:FlyBase. | 28 | P15153 | 192 | RAC2_HUMAN Ras-related C3 botulinum toxin sub... | 183 | 9e-90 | 268 | 68 | 80 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.::GO:0060263; P:regulation of respiratory burst; IDA:BHF-UCL.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 29 | Q9TU25 | 192 | RAC2_BOVIN Ras-related C3 botulinum toxin sub... | 192 | 2e-89 | 267 | 66 | 78 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 30 | Q05144 | 192 | RAC2_MOUSE Ras-related C3 botulinum toxin sub... | 186 | 6e-89 | 266 | 67 | 79 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005635; C:nuclear envelope; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0030031; P:cell projection assembly; IDA:MGI.::GO:0006935; P:chemotaxis; IDA:MGI.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 31 | P60764 | 192 | RAC3_MOUSE Ras-related C3 botulinum toxin sub... | 189 | 6e-88 | 263 | 68 | 79 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0030031; P:cell projection assembly; ISS:UniProtKB.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0031175; P:neuron projection development; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
