rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q62481 | 368 | VPS72_MOUSE Vacuolar protein sorting-associat... | 242 | 0.0002 | 47.8 | 31 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035019; P:somatic stem cell maintenance; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q5R5V9 | 364 | VPS72_PONAB Vacuolar protein sorting-associat... | 242 | 0.0003 | 47 | 31 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q15906 | 364 | VPS72_HUMAN Vacuolar protein sorting-associat... | 242 | 0.0004 | 46.6 | 31 | 43 | GO:0005634; C:nucleus; TAS:ProtInc.::GO:0043234; C:protein complex; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q6GNJ8 | 353 | VPS72_XENLA Vacuolar protein sorting-associat... | 277 | 0.002 | 44.3 | 26 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q03388 | 795 | VPS72_YEAST Vacuolar protein sorting-associat... | 301 | 0.002 | 44.7 | 28 | 44 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000812; C:Swr1 complex; IDA:SGD. | | | | | | | | | | GO:0042393; F:histone binding; IPI:SGD. | | | | | | | | | | GO:0043486; P:histone exchange; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 6 | Q5E9F6 | 364 | VPS72_BOVIN Vacuolar protein sorting-associat... | 242 | 0.003 | 43.9 | 30 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q9P0X4 | 2223 | CAC1I_HUMAN Voltage-dependent T-type calcium ... | 110 | 0.2 | 38.5 | 28 | 41 | GO:0005891; C:voltage-gated calcium channel complex; NAS:UniProtKB. | | | | | | | | | | GO:0008332; F:low voltage-gated calcium channel activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007165; P:signal transduction; TAS:ProtInc. | 8 | Q9VKM6 | 351 | VPS72_DROME Vacuolar protein sorting-associat... | 240 | 0.6 | 36.6 | 29 | 42 | GO:0035267; C:NuA4 histone acetyltransferase complex; IPI:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016573; P:histone acetylation; IDA:UniProtKB.::GO:0043486; P:histone exchange; IDA:UniProtKB.::GO:0010629; P:negative regulation of gene expression; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | P14248 | 2452 | RPB1_PLAFD DNA-directed RNA polymerase II sub... | 145 | 2.1 | 35 | 26 | 37 | GO:0005665; C:DNA-directed RNA polymerase II, core complex; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006366; P:transcription from RNA polymerase II promoter; IEA:InterPro. | 10 | Q9P790 | 316 | VPS72_SCHPO SWR complex protein 2 OS=Schizosa... | 78 | 4 | 33.9 | 35 | 56 | GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005819; C:spindle; IDA:PomBase.::GO:0000812; C:Swr1 complex; IDA:PomBase. | | | | | | | | | | GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; NAS:PomBase. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase. | 11 | O92531 | 3016 | POLG_HCVVO Genome polyprotein OS=Hepatitis C ... | 74 | 4.4 | 34.3 | 36 | 43 | GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0044186; C:host cell lipid particle; IEA:UniProtKB-SubCell.::GO:0044191; C:host cell mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.::GO:0019028; C:viral capsid; IEA:UniProtKB-KW.::GO:0019031; C:viral envelope; IEA:InterPro.::GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0005216; F:ion channel activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.::GO:0070008; F:serine-type exopeptidase activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019087; P:transformation of host cell by virus; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro. | 12 | Q2JVR0 | 237 | GRPE_SYNJA Protein grpE OS=Yellowstone A-Prim... | 108 | 5.3 | 33.1 | 26 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000774; F:adenyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0051087; F:chaperone binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 13 | P46531 | 2555 | NOTC1_HUMAN Neurogenic locus notch homolog pr... | 95 | 6 | 33.9 | 31 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0002193; C:MAML1-RBP-Jkappa- ICN1 complex; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003180; P:aortic valve morphogenesis; IMP:BHF-UCL.::GO:2000811; P:negative regulation of anoikis; IMP:BHF-UCL.::GO:0030514; P:negative regulation of BMP signaling pathway; ISS:BHF-UCL.::GO:0010812; P:negative regulation of cell-substrate adhesion; IDA:BHF-UCL.::GO:0060253; P:negative regulation of glial cell proliferation; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; IMP:UniProtKB.::GO:0010832; P:negative regulation of myotube differentiation; ISS:UniProtKB.::GO:0048715; P:negative regulation of oligodendrocyte differentiation; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:BHF-UCL.::GO:2000974; P:negative regulation of pro-B cell differentiation; ISS:UniProtKB.::GO:2000737; P:negative regulation of stem cell differentiation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0097150; P:neuronal stem cell maintenance; IEP:UniProtKB.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0048711; P:positive regulation of astrocyte differentiation; ISS:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0046427; P:positive regulation of JAK-STAT cascade; ISS:UniProtKB.::GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; ISS:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome. |