| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q8TEJ3 | 882 | SH3R3_HUMAN SH3 domain-containing RING finger... | 89 | 0.006 | 43.1 | 31 | 46 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 2 | Q9LK03 | 717 | PERK2_ARATH Proline-rich receptor-like protei... | 59 | 0.009 | 42.4 | 37 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 3 | Q8C120 | 878 | SH3R3_MOUSE SH3 domain-containing RING finger... | 44 | 0.011 | 42.4 | 39 | 57 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 4 | Q12774 | 1597 | ARHG5_HUMAN Rho guanine nucleotide exchange f... | 42 | 0.018 | 41.6 | 40 | 62 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 5 | P16573 | 519 | CEAM1_RAT Carcinoembryonic antigen-related ce... | 37 | 0.037 | 40.4 | 57 | 70 | GO:0005887; C:integral to plasma membrane; TAS:RGD. | | | | | | | | | | GO:0019901; F:protein kinase binding; IPI:RGD. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:MGI.::GO:0007165; P:signal transduction; IDA:RGD. | 6 | Q9LP77 | 655 | Y1848_ARATH Probable inactive receptor kinase... | 42 | 0.042 | 40.4 | 43 | 69 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | Q4R729 | 692 | SH321_MACFA SH3 domain-containing protein 21 ... | 49 | 0.043 | 40.4 | 45 | 55 | | | | | | | | | | | | | | | | | | | | | | 8 | Q69ZI1 | 892 | SH3R1_MOUSE E3 ubiquitin-protein ligase SH3RF... | 63 | 0.059 | 40 | 33 | 48 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005078; F:MAP-kinase scaffold activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046328; P:regulation of JNK cascade; IDA:MGI. | 9 | P97792 | 365 | CXAR_MOUSE Coxsackievirus and adenovirus rece... | 56 | 0.068 | 39.3 | 39 | 57 | GO:0001669; C:acrosomal vesicle; IDA:MGI.::GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0044297; C:cell body; IDA:UniProtKB.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0014704; C:intercalated disc; IDA:UniProtKB.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0050839; F:cell adhesion molecule binding; ISS:UniProtKB.::GO:0071253; F:connexin binding; IPI:UniProtKB.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0061338; P:atrioventricular node impulse conduction delay; IMP:UniProtKB.::GO:0048739; P:cardiac muscle fiber development; IMP:MGI.::GO:0045216; P:cell-cell junction organization; IMP:MGI.::GO:0010669; P:epithelial structure maintenance; ISS:UniProtKB.::GO:0008354; P:germ cell migration; IEP:UniProtKB.::GO:0007157; P:heterophilic cell-cell adhesion; ISS:UniProtKB.::GO:0034109; P:homotypic cell-cell adhesion; ISS:UniProtKB.::GO:0007005; P:mitochondrion organization; IMP:MGI.::GO:0060044; P:negative regulation of cardiac muscle cell proliferation; IMP:MGI.::GO:0030593; P:neutrophil chemotaxis; ISS:UniProtKB. | 10 | A4FU49 | 640 | SH321_HUMAN SH3 domain-containing protein 21 ... | 49 | 0.071 | 39.7 | 45 | 55 | | | | | | | | | | | | | | | | | | | | | | 11 | Q71F54 | 894 | SH3R1_RAT E3 ubiquitin-protein ligase SH3RF1 ... | 65 | 0.075 | 39.7 | 32 | 48 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006917; P:induction of apoptosis; IMP:RGD. | 12 | Q28E95 | 861 | SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF... | 78 | 0.089 | 39.3 | 31 | 47 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 13 | Q6NRD3 | 826 | SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF... | 63 | 0.15 | 38.5 | 32 | 48 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 14 | Q925Q9 | 709 | SH3K1_RAT SH3 domain-containing kinase-bindin... | 35 | 0.15 | 38.5 | 46 | 69 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; TAS:RGD.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 15 | Q8R550 | 709 | SH3K1_MOUSE SH3 domain-containing kinase-bind... | 35 | 0.16 | 38.5 | 46 | 69 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 16 | Q96B97 | 665 | SH3K1_HUMAN SH3 domain-containing kinase-bind... | 35 | 0.16 | 38.5 | 46 | 69 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007267; P:cell-cell signaling; NAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB. | 17 | Q9R066 | 365 | CXAR_RAT Coxsackievirus and adenovirus recept... | 56 | 0.17 | 38.1 | 38 | 57 | GO:0001669; C:acrosomal vesicle; ISS:UniProtKB.::GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0044297; C:cell body; ISS:UniProtKB.::GO:0030175; C:filopodium; ISS:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0050839; F:cell adhesion molecule binding; ISS:UniProtKB.::GO:0071253; F:connexin binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0001618; F:viral receptor activity; TAS:RGD. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0061338; P:atrioventricular node impulse conduction delay; ISS:UniProtKB.::GO:0048739; P:cardiac muscle fiber development; ISS:UniProtKB.::GO:0045216; P:cell-cell junction organization; ISS:UniProtKB.::GO:0010669; P:epithelial structure maintenance; ISS:UniProtKB.::GO:0008354; P:germ cell migration; ISS:UniProtKB.::GO:0007157; P:heterophilic cell-cell adhesion; ISS:UniProtKB.::GO:0034109; P:homotypic cell-cell adhesion; ISS:UniProtKB.::GO:0007005; P:mitochondrion organization; ISS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; ISS:UniProtKB. | 18 | A5D8S5 | 867 | SH3R1_DANRE E3 ubiquitin-protein ligase SH3RF... | 37 | 0.2 | 38.1 | 38 | 57 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 19 | Q62417 | 1290 | SRBS1_MOUSE Sorbin and SH3 domain-containing ... | 39 | 0.21 | 38.1 | 41 | 56 | GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0001725; C:stress fiber; IDA:UniProtKB. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IDA:UniProtKB.::GO:0015758; P:glucose transport; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.::GO:0043149; P:stress fiber assembly; IDA:UniProtKB. | 20 | Q7TSG5 | 549 | SH321_MOUSE SH3 domain-containing protein 21 ... | 36 | 0.23 | 37.7 | 47 | 61 | | | | | | | | | | | | | | | | | | | | | | 21 | Q5RBR0 | 888 | SH3R1_PONAB E3 ubiquitin-protein ligase SH3RF... | 69 | 0.25 | 37.7 | 32 | 48 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 22 | Q7Z6J0 | 888 | SH3R1_HUMAN E3 ubiquitin-protein ligase SH3RF... | 69 | 0.26 | 37.7 | 32 | 48 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB. | 23 | A5D7F8 | 840 | SH3R1_BOVIN E3 ubiquitin-protein ligase SH3RF... | 54 | 0.29 | 37.7 | 33 | 46 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 24 | Q9JLQ0 | 637 | CD2AP_MOUSE CD2-associated protein OS=Mus mus... | 69 | 0.32 | 37.4 | 36 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 25 | Q6R2J8 | 703 | SRF8_ARATH Protein STRUBBELIG-RECEPTOR FAMILY... | 43 | 0.44 | 37 | 40 | 63 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | O94875 | 1100 | SRBS2_HUMAN Sorbin and SH3 domain-containing ... | 34 | 0.49 | 37 | 44 | 56 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; NAS:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 27 | P31809 | 521 | CEAM1_MOUSE Carcinoembryonic antigen-related ... | 29 | 0.54 | 36.6 | 55 | 69 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 28 | Q9BX66 | 1292 | SRBS1_HUMAN Sorbin and SH3 domain-containing ... | 34 | 0.55 | 37 | 44 | 62 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0001725; C:stress fiber; ISS:UniProtKB.::GO:0005915; C:zonula adherens; TAS:ProtInc. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005158; F:insulin receptor binding; IDA:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; ISS:BHF-UCL. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0015758; P:glucose transport; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:BHF-UCL.::GO:0043149; P:stress fiber assembly; ISS:UniProtKB. | 29 | O35413 | 1196 | SRBS2_RAT Sorbin and SH3 domain-containing pr... | 34 | 0.61 | 36.6 | 44 | 56 | GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 30 | Q8BZT2 | 735 | SH3R2_MOUSE Putative E3 ubiquitin-protein lig... | 42 | 0.62 | 36.6 | 31 | 55 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 31 | Q3UTJ2 | 1180 | SRBS2_MOUSE Sorbin and SH3 domain-containing ... | 34 | 0.62 | 36.6 | 44 | 56 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |
