| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q32NH8 | 758 | PLCD4_XENLA 1-phosphatidylinositol 4,5-bispho... | 26 | 0.095 | 35 | 54 | 69 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 32 | Q8N3E9 | 789 | PLCD3_HUMAN 1-phosphatidylinositol 4,5-bispho... | 29 | 0.17 | 34.3 | 48 | 66 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 33 | Q62077 | 1302 | PLCG1_MOUSE 1-phosphatidylinositol 4,5-bispho... | 29 | 0.18 | 34.3 | 45 | 76 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI. | 34 | A5D6R3 | 784 | PLD3A_DANRE 1-phosphatidylinositol 4,5-bispho... | 27 | 0.2 | 33.9 | 52 | 70 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 35 | Q3USB7 | 1096 | PLCL1_MOUSE Inactive phospholipase C-like pro... | 34 | 0.26 | 33.9 | 44 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0050811; F:GABA receptor binding; TAS:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007610; P:behavior; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:InterPro. | 36 | Q15111 | 1095 | PLCL1_HUMAN Inactive phospholipase C-like pro... | 34 | 0.27 | 33.5 | 44 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; TAS:ProtInc.::GO:0006629; P:lipid metabolic process; IEA:InterPro. | 37 | Q02158 | 801 | PLC_DICDI 1-phosphatidylinositol 4,5-bisphosp... | 31 | 0.27 | 33.5 | 48 | 68 | | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IMP:dictyBase.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032959; P:inositol trisphosphate biosynthetic process; IMP:dictyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0050922; P:negative regulation of chemotaxis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; TAS:dictyBase. | 38 | P08487 | 1291 | PLCG1_BOVIN 1-phosphatidylinositol 4,5-bispho... | 28 | 0.43 | 33.1 | 46 | 79 | GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; ISS:AgBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB. | 39 | Q62711 | 772 | PLCD4_RAT 1-phosphatidylinositol 4,5-bisphosp... | 26 | 0.44 | 33.1 | 50 | 77 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; TAS:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 40 | P10686 | 1290 | PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosp... | 28 | 0.48 | 33.1 | 46 | 79 | GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006816; P:calcium ion transport; IMP:RGD.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0032959; P:inositol trisphosphate biosynthetic process; IMP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IMP:RGD.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:RGD.::GO:0009306; P:protein secretion; IMP:RGD.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD. | 41 | P19174 | 1290 | PLCG1_HUMAN 1-phosphatidylinositol 4,5-bispho... | 28 | 0.48 | 33.1 | 46 | 79 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0045766; P:positive regulation of angiogenesis; IDA:DFLAT.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 42 | Q4KWH5 | 1682 | PLCH1_MOUSE 1-phosphatidylinositol 4,5-bispho... | 30 | 0.7 | 32.3 | 37 | 73 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 43 | Q4KWH8 | 1693 | PLCH1_HUMAN 1-phosphatidylinositol 4,5-bispho... | 24 | 0.7 | 32.3 | 46 | 83 | GO:0031965; C:nuclear membrane; IDA:HPA. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0050429; F:calcium-dependent phospholipase C activity; IDA:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IDA:MGI. | 44 | P32383 | 869 | PLC1_YEAST 1-phosphatidylinositol 4,5-bisphos... | 34 | 1.8 | 31.2 | 38 | 68 | GO:0000775; C:chromosome, centromeric region; IDA:SGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032958; P:inositol phosphate biosynthetic process; IMP:SGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IDA:SGD.::GO:0034501; P:protein localization to kinetochore; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IGI:SGD. | 45 | Q8GV43 | 613 | PLCD6_ARATH Phosphoinositide phospholipase C ... | 39 | 2.7 | 30.8 | 33 | 64 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 46 | Q9QW07 | 1175 | PLCB4_RAT 1-phosphatidylinositol 4,5-bisphosp... | 28 | 3.1 | 30.4 | 50 | 68 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0043267; P:negative regulation of potassium ion transport; IMP:RGD.::GO:0007602; P:phototransduction; NAS:RGD. | 47 | Q15147 | 1175 | PLCB4_HUMAN 1-phosphatidylinositol 4,5-bispho... | 28 | 3.2 | 30.4 | 50 | 68 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 48 | O13433 | 1099 | PLC1_CANAX 1-phosphatidylinositol 4,5-bisphos... | 32 | 3.6 | 30.4 | 41 | 72 | | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 49 | Q07722 | 1023 | PLCB4_BOVIN 1-phosphatidylinositol 4,5-bispho... | 28 | 4 | 30.4 | 50 | 68 | | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 50 | Q9LY51 | 584 | PLCD7_ARATH Phosphoinositide phospholipase C ... | 39 | 7.8 | 29.3 | 31 | 64 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 51 | Q0C5Z5 | 853 | IF2_HYPNA Translation initiation factor IF-2 ... | 96 | 8.6 | 29.3 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | |
