rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q9JK66 | 465 | PRKN2_RAT E3 ubiquitin-protein ligase parkin ... | 67 | 0.000006 | 52.4 | 42 | 54 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0008021; C:synaptic vesicle; IDA:RGD. | | | | | | | | | | GO:0032403; F:protein complex binding; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0070997; P:neuron death; ISS:UniProtKB.::GO:0042551; P:neuron maturation; IEP:RGD.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0010506; P:regulation of autophagy; ISS:UniProtKB.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0006986; P:response to unfolded protein; IDA:RGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 62 | Q5UQ35 | 990 | YR811_MIMIV Putative ariadne-like RING finger... | 44 | 0.000007 | 52.8 | 52 | 61 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 63 | Q96EP0 | 1072 | RNF31_HUMAN E3 ubiquitin-protein ligase RNF31... | 336 | 0.000009 | 52.4 | 21 | 36 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0071797; C:LUBAC complex; IDA:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0023035; P:CD40 signaling pathway; ISS:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB. | 64 | Q924T7 | 1066 | RNF31_MOUSE E3 ubiquitin-protein ligase RNF31... | 337 | 0.00001 | 51.6 | 21 | 36 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:MGI.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0023035; P:CD40 signaling pathway; IMP:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 65 | O60260 | 465 | PRKN2_HUMAN E3 ubiquitin-protein ligase parki... | 67 | 0.00003 | 50.1 | 39 | 52 | GO:0016235; C:aggresome; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0051087; F:chaperone binding; IPI:BHF-UCL.::GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070842; P:aggresome assembly; IMP:BHF-UCL.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0000422; P:mitochondrion degradation; IMP:UniProtKB.::GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0060548; P:negative regulation of cell death; IDA:BHF-UCL.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:BHF-UCL.::GO:0070997; P:neuron death; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB. | 66 | Q04638 | 464 | ITT1_YEAST Translation termination inhibitor ... | 35 | 0.007 | 42.7 | 43 | 63 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006449; P:regulation of translational termination; IMP:SGD. | 67 | E6ZIJ1 | 707 | HOIL1_DICLA RanBP-type and C3HC4-type zinc fi... | 220 | 0.007 | 42.7 | 23 | 36 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 68 | Q9NWF9 | 866 | RN216_HUMAN E3 ubiquitin-protein ligase RNF21... | 202 | 0.021 | 41.2 | 23 | 40 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0050691; P:regulation of defense response to virus by host; IDA:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; IDA:UniProtKB. | 69 | A9JTG5 | 714 | HOIL1_DANRE RanBP-type and C3HC4-type zinc fi... | 232 | 0.035 | 40.4 | 23 | 36 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:ZFIN.::GO:0071600; P:otic vesicle morphogenesis; IMP:ZFIN.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 70 | P58283 | 853 | RN216_MOUSE E3 ubiquitin-protein ligase RNF21... | 202 | 0.071 | 39.7 | 22 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0050691; P:regulation of defense response to virus by host; ISS:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; ISS:UniProtKB. | 71 | Q6GZQ2 | 324 | 073L_FRG3G Uncharacterized protein 073L OS=Fr... | 96 | 0.29 | 37.4 | 27 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 72 | Q7YRV4 | 469 | RO52_BOVIN E3 ubiquitin-protein ligase TRIM21... | 70 | 0.75 | 36.2 | 31 | 47 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 73 | Q9BYM8 | 510 | HOIL1_HUMAN RanBP-type and C3HC4-type zinc fi... | 29 | 3.8 | 33.9 | 38 | 59 | GO:0071797; C:LUBAC complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB. | 74 | Q62921 | 508 | HOIL1_RAT RanBP-type and C3HC4-type zinc fing... | 29 | 4.3 | 33.9 | 38 | 59 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 75 | Q9WUB0 | 508 | HOIL1_MOUSE RanBP-type and C3HC4-type zinc fi... | 29 | 4.3 | 33.5 | 38 | 59 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 76 | Q8N448 | 690 | LNX2_HUMAN Ligand of Numb protein X 2 OS=Homo... | 36 | 5.1 | 33.5 | 36 | 58 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 77 | O10339 | 249 | VCG3_NPVOP Zinc finger protein CG30 OS=Orgyia... | 73 | 5.6 | 32.7 | 30 | 40 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 78 | O13762 | 897 | YF2C_SCHPO Uncharacterized ATP-dependent heli... | 60 | 6.6 | 33.1 | 32 | 45 | GO:0016585; C:chromatin remodeling complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; ISS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0006281; P:DNA repair; ISS:PomBase. | 79 | Q753V5 | 1085 | RAD5_ASHGO DNA repair protein RAD5 OS=Y-1056)... | 72 | 7.3 | 33.1 | 32 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 80 | Q91XL2 | 687 | LNX2_MOUSE Ligand of Numb protein X 2 OS=Mus ... | 36 | 8.1 | 32.7 | 36 | 58 | | | | | | | | | | | GO:0030165; F:PDZ domain binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051260; P:protein homooligomerization; IDA:MGI. | 81 | Q9SYU4 | 381 | PEX10_ARATH Peroxisome biogenesis factor 10 O... | 52 | 9.1 | 32.3 | 31 | 44 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010381; P:attachment of peroxisome to chloroplast; IMP:TAIR.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0006635; P:fatty acid beta-oxidation; IMP:TAIR.::GO:0009853; P:photorespiration; IMP:TAIR.::GO:0016558; P:protein import into peroxisome matrix; IMP:TAIR. |