| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | A2AAY5 | 908 | SPD2B_MOUSE SH3 and PX domain-containing prot... | 136 | 0.0000004 | 57.4 | 28 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:UniProtKB.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB. | | | | | | | | | | GO:0060612; P:adipose tissue development; IMP:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; IMP:UniProtKB.::GO:0045600; P:positive regulation of fat cell differentiation; IMP:UniProtKB.::GO:0072657; P:protein localization in membrane; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB. | 92 | Q62419 | 368 | SH3G1_MOUSE Endophilin-A2 OS=Mus musculus (Mo... | 56 | 0.025 | 41.6 | 34 | 59 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 93 | O35964 | 368 | SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus ... | 56 | 0.023 | 41.6 | 34 | 59 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:RGD.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; IPI:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 94 | Q62421 | 347 | SH3G3_MOUSE Endophilin-A3 OS=Mus musculus (Mo... | 50 | 0.002 | 45.1 | 36 | 64 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 95 | Q5BBL4 | 581 | HSE1_EMENI Class E vacuolar protein-sorting m... | 75 | 0.000003 | 54.3 | 40 | 56 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 96 | O35180 | 347 | SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus ... | 50 | 0.002 | 44.7 | 36 | 64 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 97 | Q99963 | 347 | SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens (Hu... | 50 | 0.025 | 41.6 | 34 | 60 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 98 | Q9NYB9 | 513 | ABI2_HUMAN Abl interactor 2 OS=Homo sapiens (... | 60 | 0.0005 | 47 | 38 | 57 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI. | 99 | P62484 | 446 | ABI2_MOUSE Abl interactor 2 OS=Mus musculus (... | 60 | 0.002 | 44.7 | 37 | 57 | GO:0005913; C:cell-cell adherens junction; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:MGI.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0016358; P:dendrite development; IMP:MGI.::GO:0007611; P:learning or memory; IMP:MGI. | 100 | Q1LYG0 | 1119 | SPD2A_DANRE SH3 and PX domain-containing prot... | 50 | 2.7 | 35.4 | 34 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB. | 101 | Q75DS3 | 443 | HSE1_ASHGO Class E vacuolar protein-sorting m... | 72 | 0.00008 | 49.7 | 35 | 54 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 102 | Q62077 | 1302 | PLCG1_MOUSE 1-phosphatidylinositol 4,5-bispho... | 75 | 0.0000008 | 56.6 | 41 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI. | 103 | Q14847 | 261 | LASP1_HUMAN LIM and SH3 domain protein 1 OS=H... | 68 | 0.00005 | 49.7 | 35 | 53 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB. | | | | | | | | | | GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 104 | Q5R5W0 | 261 | LASP1_PONAB LIM and SH3 domain protein 1 OS=P... | 68 | 0.00005 | 49.3 | 35 | 53 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 105 | P10686 | 1290 | PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosp... | 75 | 0.0000009 | 56.6 | 41 | 55 | GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006816; P:calcium ion transport; IMP:RGD.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0032959; P:inositol trisphosphate biosynthetic process; IMP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IMP:RGD.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:RGD.::GO:0009306; P:protein secretion; IMP:RGD.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD. | 106 | Q61792 | 263 | LASP1_MOUSE LIM and SH3 domain protein 1 OS=M... | 64 | 0.00004 | 49.7 | 36 | 55 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:MGI.::GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 107 | Q8C120 | 878 | SH3R3_MOUSE SH3 domain-containing RING finger... | 54 | 1.5 | 36.2 | 39 | 48 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 108 | Q99MZ8 | 263 | LASP1_RAT LIM and SH3 domain protein 1 OS=Rat... | 64 | 0.00004 | 49.7 | 36 | 55 | GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0015075; F:ion transmembrane transporter activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 109 | A1X283 | 911 | SPD2B_HUMAN SH3 and PX domain-containing prot... | 148 | 0.000001 | 56.2 | 27 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0060612; P:adipose tissue development; ISS:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; ISS:UniProtKB.::GO:0072657; P:protein localization in membrane; IDA:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. | 110 | Q0U6X7 | 618 | HSE1_PHANO Class E vacuolar protein-sorting m... | 72 | 0.000006 | 53.5 | 32 | 56 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 111 | Q6CVA8 | 508 | HSE1_KLULA Class E vacuolar protein-sorting m... | 56 | 0.0004 | 47.8 | 36 | 57 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 112 | Q8NFA2 | 376 | NOXO1_HUMAN NADPH oxidase organizer 1 OS=Homo... | 138 | 0.000001 | 55.1 | 26 | 38 | GO:0043020; C:NADPH oxidase complex; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016176; F:superoxide-generating NADPH oxidase activator activity; TAS:BHF-UCL. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.::GO:0060263; P:regulation of respiratory burst; TAS:BHF-UCL. | 113 | Q9QZM5 | 476 | ABI1_RAT Abl interactor 1 OS=Rattus norvegicu... | 60 | 0.0007 | 46.6 | 40 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 114 | Q6FN49 | 450 | HSE1_CANGA Class E vacuolar protein-sorting m... | 56 | 0.001 | 45.8 | 36 | 55 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 115 | Q8IZP0 | 508 | ABI1_HUMAN Abl interactor 1 OS=Homo sapiens (... | 60 | 0.0002 | 48.9 | 40 | 58 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:ProtInc.::GO:0005783; C:endoplasmic reticulum; TAS:ProtInc.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; TAS:ProtInc. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0006928; P:cellular component movement; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc. | 116 | Q8CBW3 | 481 | ABI1_MOUSE Abl interactor 1 OS=Mus musculus (... | 60 | 0.0008 | 46.6 | 40 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0030296; F:protein tyrosine kinase activator activity; IDA:MGI. | | | | | | | | | | GO:0001756; P:somitogenesis; IMP:MGI. | 117 | Q3SZ01 | 341 | SH3Y1_BOVIN SH3 domain-containing YSC84-like ... | 52 | 0.55 | 37 | 35 | 52 | | | | | | | | | | | | | | | | | | | | | | 118 | A4RF61 | 718 | HSE1_MAGO7 Class E vacuolar protein-sorting m... | 59 | 0.00002 | 52.4 | 36 | 59 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 119 | Q7T2D0 | 755 | SGSM3_DANRE Small G protein signaling modulat... | 74 | 1.1 | 36.6 | 24 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 120 | Q4WHP5 | 584 | HSE1_ASPFU Class E vacuolar protein-sorting m... | 117 | 0.000003 | 54.3 | 28 | 49 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 121 | Q1E878 | 612 | HSE1_COCIM Class E vacuolar protein-sorting m... | 86 | 0.000003 | 54.7 | 38 | 53 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. |
