Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Blastomyces dermatitidis LH 1408.1
Locus:
BDBG_00082
Length:
1181
Number of sequences:
9555
Description:
rho GTPase activator
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1O43052    1150   RGA1_SCHPO Rho-type GTPase-activating protein...10750     798     41     58GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005100; F:Rho GTPase activator activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0030036; P:actin cytoskeleton organization; IMP:PomBase.::GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro.
2P35688    1017   LRG1_YEAST Rho-GTPase-activating protein LRG1...10072e-151     487     32     48GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005100; F:Rho GTPase activator activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009272; P:fungal-type cell wall biogenesis; IGI:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
3Q8VI36    591   PAXI_MOUSE Paxillin OS=Mus musculus (Mouse). ...543.5     35.4     31     48GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.
GO:0051435; F:BH4 domain binding; IPI:MGI.::GO:0030159; F:receptor signaling complex scaffold activity; TAS:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000187; P:activation of MAPK activity; IDA:MGI.::GO:0048754; P:branching morphogenesis of a tube; IDA:MGI.::GO:0006928; P:cellular component movement; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0048041; P:focal adhesion assembly; IDA:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.
4P49024    559   PAXI_CHICK Paxillin OS=Gallus gallus (Chicken...1390.14     40     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
5P49023    591   PAXI_HUMAN Paxillin OS=Homo sapiens (Human). ...543.6     35.4     31     48GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:BHF-UCL.::GO:0030027; C:lamellipodium; IDA:BHF-UCL.::GO:0005875; C:microtubule associated complex; TAS:ProtInc.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0017166; F:vinculin binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0034614; P:cellular response to reactive oxygen species; IEP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.::GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0007172; P:signal complex assembly; TAS:ProtInc.
6Q5R7I1    591   PAXI_PONAB Paxillin OS=Pongo abelii (Sumatran...543.6     35.4     31     48GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
7Q66H76    586   PAXI_RAT Paxillin OS=Rattus norvegicus (Rat)....1441.4     36.6     24     42GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.
GO:0005178; F:integrin binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
8Q09476    413   PXL1_CAEEL Paxillin homolog 1 OS=Caenorhabdit...573.4     35.4     32     46GO:0005912; C:adherens junction; IDA:WormBase.::GO:0031430; C:M band; IDA:WormBase.::GO:0002102; C:podosome; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase.
GO:0017166; F:vinculin binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0061061; P:muscle structure development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0043050; P:pharyngeal pumping; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.
9Q62219    461   TGFI1_MOUSE Transforming growth factor beta-1...624     35     31     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045165; P:cell fate commitment; IGI:MGI.::GO:0030855; P:epithelial cell differentiation; IGI:MGI.::GO:0016331; P:morphogenesis of embryonic epithelium; IMP:MGI.::GO:0045599; P:negative regulation of fat cell differentiation; IGI:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
10Q99PD6    461   TGFI1_RAT Transforming growth factor beta-1-i...624.4     35     31     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; TAS:RGD.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009408; P:response to heat; IDA:RGD.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
11Q3MHZ4    456   TGFI1_BOVIN Transforming growth factor beta-1...851.7     36.2     31     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
12O43294    461   TGFI1_HUMAN Transforming growth factor beta-1...832     36.2     30     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0048495; F:Roundabout binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
13Q99N69    386   LPXN_MOUSE Leupaxin OS=Mus musculus (Mouse). ...332.7     35.4     42     64GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0050859; P:negative regulation of B cell receptor signaling pathway; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q2TCH4    506   TGFI1_XENLA Transforming growth factor beta-1...572.9     35.4     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
15O60711    386   LPXN_HUMAN Leupaxin OS=Homo sapiens (Human). ...423     35.4     36     57GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; NAS:ProtInc.::GO:0050859; P:negative regulation of B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.::GO:0006461; P:protein complex assembly; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q9N261    386   LPXN_RABIT Leupaxin OS=Oryctolagus cuniculus ...332.3     35.8     42     64GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17Q8MML5    569   PAXB_DICDI Paxillin-B OS=Dictyostelium discoi...621     37     26     44GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0032433; C:filopodium tip; IDA:dictyBase.::GO:0005925; C:focal adhesion; IDA:dictyBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016339; P:calcium-dependent cell-cell adhesion; IMP:dictyBase.::GO:0016477; P:cell migration; IMP:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0007109; P:cytokinesis, completion of separation; IMP:dictyBase.
18Q54NW4    553   LIMB_DICDI LIM domain-containing protein B OS...1140.0000002     58.5     31     47GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; ISS:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0007155; P:cell adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.
19Q8BN58    729   RHG28_MOUSE Rho GTPase-activating protein 28 ...3790.000000000000007     83.2     23     42
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
20O14639    778   ABLM1_HUMAN Actin-binding LIM protein 1 OS=Ho...1060.0000003     58.5     33     47GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007601; P:visual perception; TAS:ProtInc.
21Q6INU3    421   PDLI7_XENLA PDZ and LIM domain protein 7 OS=X...1660.00000000000003     80.1     32     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
22O75112    727   LDB3_HUMAN LIM domain-binding protein 3 OS=Ho...1220.00000004     61.6     29     42GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
23Q8K4G5    861   ABLM1_MOUSE Actin-binding LIM protein 1 OS=Mu...1130.0000001     60.1     32     47GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
24Q9Z1Z9    457   PDLI7_RAT PDZ and LIM domain protein 7 OS=Rat...1570.0000000000002     77.8     31     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0045669; P:positive regulation of osteoblast differentiation; IDA:RGD.
25Q9NR12    457   PDLI7_HUMAN PDZ and LIM domain protein 7 OS=H...1570.0000000000002     77.8     31     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
26Q3TJD7    457   PDLI7_MOUSE PDZ and LIM domain protein 7 OS=M...1570.0000000000002     77.4     31     44GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.::GO:0001725; C:stress fiber; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IPI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.
27Q9JKS4    723   LDB3_MOUSE LIM domain-binding protein 3 OS=Mu...1930.0000000000003     78.2     26     44GO:0005856; C:cytoskeleton; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI.
GO:0005080; F:protein kinase C binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
28Q3SX40    424   PDLI7_BOVIN PDZ and LIM domain protein 7 OS=B...1660.0000000000007     75.9     31     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.
29Q6P4F7    1023   RHGBA_HUMAN Rho GTPase-activating protein 11A...2160.000000000002     75.9     30     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
30A1ZA47    2194   ZASP_DROME PDZ and LIM domain protein Zasp OS...350.34     38.9     40     54GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005927; C:muscle tendon junction; IDA:FlyBase.::GO:0030018; C:Z disc; IDA:FlyBase.
GO:0003779; F:actin binding; IPI:UniProtKB.::GO:0051371; F:muscle alpha-actinin binding; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0061061; P:muscle structure development; IMP:FlyBase.::GO:0001952; P:regulation of cell-matrix adhesion; IMP:UniProtKB.
31Q55BI0    186   Y6787_DICDI LIM domain-containing protein DDB...762.6     34.7     32     39
GO:0008270; F:zinc ion binding; IEA:InterPro.
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