Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Blastomyces dermatitidis LH 1408.1
Locus:
BDBG_00082
Length:
1181
Number of sequences:
9555
Description:
rho GTPase activator
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q80Y24    845   PRIC2_MOUSE Prickle-like protein 2 OS=Mus mus...602.9     35.8     35     47GO:0016327; C:apicolateral plasma membrane; IDA:MGI.::GO:0016328; C:lateral plasma membrane; IDA:MGI.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IDA:MGI.::GO:0031175; P:neuron projection development; IMP:MGI.
92P50464    348   UNC97_CAEEL LIM domain-containing protein unc...710.78     37.4     32     42GO:0005912; C:adherens junction; IDA:WormBase.::GO:0031430; C:M band; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase.
GO:0017022; F:myosin binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045216; P:cell-cell junction organization; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0050954; P:sensory perception of mechanical stimulus; IMP:WormBase.::GO:0061199; P:striated muscle contraction involved in embryonic body morphogenesis; IMP:WormBase.
93Q8WUP2    373   FBLI1_HUMAN Filamin-binding LIM protein 1 OS=...1450.00000005     60.1     31     44GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0001725; C:stress fiber; IDA:UniProtKB.
GO:0031005; F:filamin binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0016337; P:cell-cell adhesion; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; IMP:UniProtKB.
94Q28FG2    833   PRIC1_XENTR Prickle-like protein 1 OS=Xenopus...1570.00000006     60.8     27     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
95Q15942    572   ZYX_HUMAN Zyxin OS=Homo sapiens (Human). GN=Z...1410.0000005     57.4     28     40GO:0005913; C:cell-cell adherens junction; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
96A1Z6W3    1299   PRIC1_DROME Protein prickle OS=Drosophila mel...1450.00000006     60.8     29     42GO:0005737; C:cytoplasm; TAS:FlyBase.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; IMP:UniProtKB.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; IMP:FlyBase.::GO:0042067; P:establishment of ommatidial planar polarity; IMP:FlyBase.::GO:0045184; P:establishment of protein localization; TAS:FlyBase.::GO:0045185; P:maintenance of protein location; TAS:FlyBase.
97Q9Z1N3    2626   MYO9A_RAT Unconventional myosin-IXa OS=Rattus...1950.00000007     60.8     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
98Q90Z06    835   PRI1A_XENLA Prickle-like protein 1-A OS=Xenop...950.066     41.2     23     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; IMP:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; IMP:UniProtKB.::GO:0001736; P:establishment of planar polarity; IMP:UniProtKB.
99P53670    638   LIMK2_RAT LIM domain kinase 2 OS=Rattus norve...920.002     45.8     33     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007286; P:spermatid development; TAS:RGD.
100P53666    642   LIMK2_CHICK LIM domain kinase 2 OS=Gallus gal...910.0001     50.1     30     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
101Q1JQB5    378   FBLI1_BOVIN Filamin-binding LIM protein 1 OS=...1450.0000001     59.3     31     45GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB.
GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB.
102P50481    400   LHX3_MOUSE LIM/homeobox protein Lhx3 OS=Mus m...1310.0000001     59.3     27     46GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0021526; P:medial motor column neuron differentiation; IGI:MGI.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0021527; P:spinal cord association neuron differentiation; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0021521; P:ventral spinal cord interneuron specification; IDA:MGI.
103Q8N264    748   RHG24_HUMAN Rho GTPase-activating protein 24 ...2440.0000001     59.7     26     43GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
104Q6ZUM4    889   RHG27_HUMAN Rho GTPase-activating protein 27 ...2080.0000001     59.7     25     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; ISS:HGNC.::GO:0017124; F:SH3 domain binding; ISS:HGNC.
GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:HGNC.::GO:0006898; P:receptor-mediated endocytosis; ISS:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro.
105Q13642    323   FHL1_HUMAN Four and a half LIM domains protei...1791.7     36.2     21     37GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; NAS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0009887; P:organ morphogenesis; NAS:UniProtKB.
106Q292U5    795   ESN_DROPS Protein espinas OS=Drosophila pseud...588.3     34.3     33     48
GO:0008270; F:zinc ion binding; IEA:InterPro.
107Q9UBR4    397   LHX3_HUMAN LIM/homeobox protein Lhx3 OS=Homo ...1450.0000001     58.9     27     44GO:0005634; C:nucleus; TAS:ProtInc.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048839; P:inner ear development; IEP:UniProtKB.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
108Q5REN1    375   FBLI1_PONAB Filamin-binding LIM protein 1 OS=...1450.0000001     58.9     30     44GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB.
GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB.
109O54785    638   LIMK2_MOUSE LIM domain kinase 2 OS=Mus muscul...920.005     44.7     33     48GO:0005801; C:cis-Golgi network; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007283; P:spermatogenesis; IMP:MGI.
110Q06BR1    612   LIMD1_XENLA LIM domain-containing protein 1 O...1650.00002     52.8     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
111Q91XC0    547   AJUBA_MOUSE LIM domain-containing protein aju...1330.0004     48.1     26     44GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0051015; F:actin filament binding; IDA:MGI.::GO:0045294; F:alpha-catenin binding; IDA:MGI.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016339; P:calcium-dependent cell-cell adhesion; IMP:MGI.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IMP:MGI.::GO:0048041; P:focal adhesion assembly; IMP:MGI.::GO:0046474; P:glycerophospholipid biosynthetic process; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0033673; P:negative regulation of kinase activity; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0031328; P:positive regulation of cellular biosynthetic process; IMP:MGI.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:MGI.::GO:0030334; P:regulation of cell migration; IDA:MGI.::GO:0043087; P:regulation of GTPase activity; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035313; P:wound healing, spreading of epidermal cells; IMP:MGI.
112Q5U2Z2    548   AJUBA_RAT LIM domain-containing protein ajuba...1330.0004     48.1     26     44GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
113Q292U2    1353   PRIC1_DROPS Protein prickle OS=Drosophila pse...1790.0000002     59.3     27     40GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
114O35115    279   FHL2_RAT Four and a half LIM domains protein ...980.08     40     26     41GO:0031430; C:M band; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:RGD.
GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
115Q80W90    388   LHX9_RAT LIM/homeobox protein Lhx9 OS=Rattus ...920.00001     52.4     27     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
116Q8BL80    702   RHG22_MOUSE Rho GTPase-activating protein 22 ...2590.0000003     58.5     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
117Q96IF1    538   AJUBA_HUMAN LIM domain-containing protein aju...1230.0006     47.4     27     44GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0000932; C:cytoplasmic mRNA processing body; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0045294; F:alpha-catenin binding; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0035195; P:gene silencing by miRNA; IMP:MGI.::GO:0035331; P:negative regulation of hippo signaling cascade; IDA:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.::GO:0031334; P:positive regulation of protein complex assembly; IDA:MGI.::GO:1900037; P:regulation of cellular response to hypoxia; IDA:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
118E1BKA3    548   AJUBA_BOVIN LIM domain-containing protein aju...1330.0006     47.8     26     44GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
119Q9NQ69    397   LHX9_HUMAN LIM/homeobox protein Lhx9 OS=Homo ...920.00002     52.4     27     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
120P53671    638   LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapie...950.003     45.4     32     45GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042325; P:regulation of phosphorylation; IEA:InterPro.
121O97581    383   LHX3_PIG LIM/homeobox protein Lhx3 OS=Sus scr...1240.0000004     57.4     27     45GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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