rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | Q9NYF5 | 915 | FA13B_HUMAN Protein FAM13B OS=Homo sapiens (H... | 109 | 0.52 | 38.1 | 30 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 422 | Q12128 | 409 | BAG7_YEAST Rho-GTPase-activating protein BAG7... | 118 | 0.54 | 37.7 | 26 | 48 | GO:0005622; C:intracellular; TAS:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD. | 423 | O00151 | 329 | PDLI1_HUMAN PDZ and LIM domain protein 1 OS=H... | 71 | 1.5 | 36.2 | 34 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006979; P:response to oxidative stress; TAS:ProtInc. | 424 | Q54Y72 | 338 | GACA_DICDI Rho GTPase-activating protein gacA... | 205 | 0.56 | 37.7 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 425 | Q8R5G7 | 1538 | ARAP3_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 80 | 0.62 | 38.1 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0035021; P:negative regulation of Rac protein signal transduction; IDA:MGI.::GO:0035024; P:negative regulation of Rho protein signal transduction; IDA:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 426 | Q8WWN8 | 1544 | ARAP3_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 78 | 0.63 | 38.1 | 32 | 51 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0035024; P:negative regulation of Rho protein signal transduction; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB. | 427 | Q80XB4 | 1728 | NRAP_MOUSE Nebulin-related-anchoring protein ... | 53 | 0.71 | 37.7 | 32 | 49 | GO:0005916; C:fascia adherens; IDA:UniProtKB.::GO:0005927; C:muscle tendon junction; IDA:UniProtKB.::GO:0030016; C:myofibril; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0051371; F:muscle alpha-actinin binding; IDA:UniProtKB.::GO:0017166; F:vinculin binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:MGI. | 428 | Q9VDG2 | 625 | RLIP_DROME RalA-binding protein 1 OS=Drosophi... | 103 | 0.74 | 37.7 | 30 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:FlyBase. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 429 | P0C7Q8 | 532 | DA1_ARATH Protein DA1 OS=Arabidopsis thaliana... | 88 | 0.76 | 37.4 | 24 | 43 | | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046621; P:negative regulation of organ growth; IMP:TAIR.::GO:0048482; P:ovule morphogenesis; IMP:TAIR.::GO:0048317; P:seed morphogenesis; IMP:TAIR. | 430 | Q9V9S7 | 1866 | SYDE_DROME Rho GTPase-activating protein 100F... | 115 | 0.81 | 37.7 | 20 | 48 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0048786; C:presynaptic active zone; IDA:FlyBase. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; IMP:FlyBase.::GO:0048790; P:maintenance of presynaptic active zone structure; IMP:FlyBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 431 | Q2TBC4 | 344 | PRIC4_HUMAN Prickle-like protein 4 OS=Homo sa... | 68 | 0.99 | 37 | 28 | 40 | GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 432 | Q6Y5D8 | 786 | RHG10_MOUSE Rho GTPase-activating protein 10 ... | 236 | 1.1 | 37.4 | 24 | 42 | GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IPI:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 433 | Q8WWI1 | 1683 | LMO7_HUMAN LIM domain only protein 7 OS=Homo ... | 81 | 1.1 | 37.4 | 32 | 42 | GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0000151; C:ubiquitin ligase complex; NAS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 434 | Q17QE2 | 363 | LMCD1_BOVIN LIM and cysteine-rich domains pro... | 68 | 1.1 | 37 | 26 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; ISS:UniProtKB.::GO:0010611; P:regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 435 | A1A4S6 | 786 | RHG10_HUMAN Rho GTPase-activating protein 10 ... | 189 | 1.1 | 37 | 24 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 436 | Q86VF7 | 1730 | NRAP_HUMAN Nebulin-related-anchoring protein ... | 53 | 1.2 | 37 | 32 | 49 | GO:0005916; C:fascia adherens; ISS:UniProtKB.::GO:0005927; C:muscle tendon junction; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0051371; F:muscle alpha-actinin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 437 | Q5PXT2 | 363 | LMCD1_PIG LIM and cysteine-rich domains prote... | 68 | 1.2 | 36.6 | 26 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; ISS:UniProtKB.::GO:0010611; P:regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 438 | O70400 | 327 | PDLI1_MOUSE PDZ and LIM domain protein 1 OS=M... | 71 | 1.3 | 36.6 | 34 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0003713; F:transcription coactivator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IDA:MGI. | 439 | Q8BQN6 | 292 | OZF_MOUSE Zinc finger protein OZF OS=Mus musc... | 153 | 1.3 | 36.2 | 25 | 38 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 440 | Q10007 | 268 | HLH6_CAEEL Helix-loop-helix protein 6 OS=Caen... | 55 | 1.5 | 36.2 | 42 | 55 | GO:0005634; C:nucleus; ISS:WormBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:WormBase. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0035264; P:multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0060465; P:pharynx development; IMP:WormBase. | 441 | Q9BRR9 | 750 | RHG09_HUMAN Rho GTPase-activating protein 9 O... | 74 | 1.5 | 36.6 | 24 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 442 | P52757 | 468 | CHIO_HUMAN Beta-chimaerin OS=Homo sapiens (Hu... | 177 | 1.6 | 36.6 | 21 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 443 | Q8SSN9 | 1140 | GACF_DICDI Rho GTPase-activating protein gacF... | 78 | 1.8 | 36.6 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 444 | P52944 | 327 | PDLI1_RAT PDZ and LIM domain protein 1 OS=Rat... | 58 | 1.9 | 35.8 | 34 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001666; P:response to hypoxia; IEP:RGD. | 445 | P18733 | 606 | ZG66_XENLA Gastrula zinc finger protein XlCGF... | 86 | 1.9 | 36.2 | 28 | 37 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 446 | Q8N103 | 731 | TAGAP_HUMAN T-cell activation Rho GTPase-acti... | 210 | 2.1 | 36.2 | 21 | 39 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 447 | Q5T5D7 | 378 | ZN684_HUMAN Zinc finger protein 684 OS=Homo s... | 112 | 2.1 | 35.8 | 23 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 448 | Q972V9 | 219 | URE23_SULTO Urease subunit gamma/beta OS=Sulf... | 92 | 2.5 | 35 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009039; F:urease activity; IEA:EC. | | | | | | | | | | | 449 | Q9DC07 | 270 | LNEBL_MOUSE LIM zinc-binding domain-containin... | 61 | 2.5 | 35.4 | 31 | 48 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 450 | Q5E9E1 | 328 | PDLI1_BOVIN PDZ and LIM domain protein 1 OS=B... | 71 | 2.5 | 35.4 | 34 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; ISS:AgBase. | | | | | | | | | | GO:0003713; F:transcription coactivator activity; ISS:AgBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; ISS:AgBase. | 451 | Q10164 | 1275 | RGA2_SCHPO Probable Rho-type GTPase-activatin... | 181 | 2.7 | 35.8 | 25 | 44 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. |