rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | Q9R059 | 289 | FHL3_MOUSE Four and a half LIM domains protei... | 139 | 7.9 | 33.9 | 29 | 42 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 392 | Q86IG9 | 566 | GACH_DICDI Rho GTPase-activating protein gacH... | 218 | 0.063 | 41.2 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 393 | Q20498 | 759 | RRC1_CAEEL GTPase-activating protein rrc-1 OS... | 123 | 0.066 | 41.2 | 21 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 394 | Q91YM2 | 1499 | RHG35_MOUSE Rho GTPase-activating protein 35 ... | 84 | 0.067 | 41.2 | 27 | 51 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; TAS:MGI. | | | | | | | | | | GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; TAS:MGI.::GO:0043116; P:negative regulation of vascular permeability; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 395 | Q4R6J4 | 378 | ZN684_MACFA Zinc finger protein 684 OS=Macaca... | 112 | 0.074 | 40.4 | 26 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 396 | Q6GPD0 | 1940 | RHG32_XENLA Rho GTPase-activating protein 32 ... | 159 | 0.082 | 41.2 | 26 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 397 | Q9WVM1 | 628 | RGAP1_MOUSE Rac GTPase-activating protein 1 O... | 148 | 0.091 | 40.4 | 23 | 42 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0097149; C:centralspindlin complex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB. | | | | | | | | | | GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; ISS:UniProtKB.::GO:0007108; P:cytokinesis, initiation of separation; ISS:UniProtKB.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007405; P:neuroblast proliferation; IEP:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 398 | Q6PGG2 | 971 | GMIP_MOUSE GEM-interacting protein OS=Mus mus... | 90 | 0.091 | 40.8 | 22 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 399 | Q69ZH9 | 1483 | RHG23_MOUSE Rho GTPase-activating protein 23 ... | 187 | 0.1 | 40.8 | 24 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 400 | Q9PW72 | 330 | PDLI4_CHICK PDZ and LIM domain protein 4 OS=G... | 31 | 0.37 | 38.1 | 45 | 55 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 401 | Q6ZW31 | 735 | SYDE1_HUMAN Rho GTPase-activating protein SYD... | 109 | 0.14 | 40 | 25 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 402 | P36202 | 330 | PDLI4_RAT PDZ and LIM domain protein 4 OS=Rat... | 52 | 0.26 | 38.5 | 35 | 50 | | | | | | | | | | | GO:0042805; F:actinin binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:RGD. | 403 | P70271 | 330 | PDLI4_MOUSE PDZ and LIM domain protein 4 OS=M... | 52 | 0.28 | 38.5 | 35 | 50 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 404 | P50479 | 330 | PDLI4_HUMAN PDZ and LIM domain protein 4 OS=H... | 52 | 0.31 | 38.5 | 35 | 52 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 405 | Q5VT97 | 1194 | SYDE2_HUMAN Rho GTPase-activating protein SYD... | 115 | 0.17 | 40 | 29 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 406 | Q801P0 | 171 | LMO4B_XENLA LIM domain transcription factor L... | 50 | 6.5 | 33.5 | 38 | 50 | | | | | | | | | | | GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 407 | Q54BP9 | 520 | GACV_DICDI Rho GTPase-activating protein gacV... | 111 | 0.19 | 39.3 | 26 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 408 | P97393 | 1501 | RHG05_MOUSE Rho GTPase-activating protein 5 O... | 87 | 0.2 | 39.7 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030335; P:positive regulation of cell migration; IMP:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:0008361; P:regulation of cell size; IMP:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 409 | Q3T005 | 331 | PDLI4_BOVIN PDZ and LIM domain protein 4 OS=B... | 52 | 0.29 | 38.5 | 35 | 50 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 410 | Q13017 | 1502 | RHG05_HUMAN Rho GTPase-activating protein 5 O... | 83 | 0.21 | 39.7 | 31 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 411 | Q9P227 | 1491 | RHG23_HUMAN Rho GTPase-activating protein 23 ... | 187 | 0.22 | 39.7 | 22 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 412 | D2H9U0 | 547 | RHG36_AILME Rho GTPase-activating protein 36 ... | 213 | 0.25 | 39.3 | 23 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 413 | Q8AW92 | 171 | LMO4A_XENLA LIM domain transcription factor L... | 50 | 7.7 | 33.1 | 38 | 50 | | | | | | | | | | | GO:0003712; F:transcription cofactor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; IMP:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 414 | Q5FVB2 | 167 | LMO41_XENTR LIM domain transcription factor L... | 50 | 7.2 | 33.1 | 38 | 50 | | | | | | | | | | | GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 415 | Q54E35 | 570 | GACEE_DICDI Rho GTPase-activating protein gac... | 102 | 0.36 | 38.5 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 416 | Q9DBZ9 | 737 | SYDE1_MOUSE Rho GTPase-activating protein SYD... | 109 | 0.4 | 38.5 | 25 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 417 | Q9NZU5 | 365 | LMCD1_HUMAN LIM and cysteine-rich domains pro... | 101 | 0.43 | 38.1 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; IMP:UniProtKB.::GO:0010611; P:regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 418 | Q86NH1 | 987 | SYD1_CAEEL Rho GTPase-activating protein syd-... | 113 | 0.44 | 38.5 | 23 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0042734; C:presynaptic membrane; IDA:WormBase. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IMP:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; IMP:UniProtKB.::GO:0008088; P:axon cargo transport; IGI:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IMP:UniProtKB.::GO:0034613; P:cellular protein localization; IGI:WormBase.::GO:0040011; P:locomotion; IGI:WormBase.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 419 | Q8K2H3 | 851 | FA13B_MOUSE Protein FAM13B OS=Mus musculus (M... | 109 | 0.45 | 38.5 | 30 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 420 | Q08DP6 | 785 | RHG10_BOVIN Rho GTPase-activating protein 10 ... | 235 | 0.5 | 38.1 | 23 | 42 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 421 | Q9NYF5 | 915 | FA13B_HUMAN Protein FAM13B OS=Homo sapiens (H... | 109 | 0.52 | 38.1 | 30 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. |