| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q55BI0 | 186 | Y6787_DICDI LIM domain-containing protein DDB... | 76 | 2.6 | 34.7 | 32 | 39 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 32 | Q8BL65 | 612 | ABLM2_MOUSE Actin-binding LIM protein 2 OS=Mu... | 93 | 0.003 | 45.4 | 24 | 43 | GO:0030016; C:myofibril; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI. | 33 | Q6KC51 | 612 | ABLM2_RAT Actin-binding LIM protein 2 OS=Ratt... | 93 | 0.002 | 46.2 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IEA:InterPro. | 34 | Q6H8Q1 | 611 | ABLM2_HUMAN Actin-binding LIM protein 2 OS=Ho... | 118 | 0.00000005 | 60.8 | 31 | 47 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro. | 35 | Q3KRB8 | 267 | RHGBB_HUMAN Rho GTPase-activating protein 11B... | 182 | 0.000000000006 | 70.9 | 30 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 36 | Q9P2N2 | 729 | RHG28_HUMAN Rho GTPase-activating protein 28 ... | 318 | 0.000000000006 | 73.6 | 25 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 37 | Q80Y19 | 987 | RHGBA_MOUSE Rho GTPase-activating protein 11A... | 179 | 0.000000000008 | 73.6 | 30 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 38 | P53667 | 647 | LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapie... | 92 | 0.000001 | 56.6 | 30 | 50 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043005; C:neuron projection; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IDA:BHF-UCL.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 39 | Q6P7E4 | 419 | PDLI7_DANRE PDZ and LIM domain protein 7 OS=D... | 157 | 0.000000000009 | 72.4 | 29 | 45 | GO:0031941; C:filamentous actin; IDA:ZFIN.::GO:0048471; C:perinuclear region of cytoplasm; IDA:ZFIN. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0003294; P:atrial ventricular junction remodeling; IMP:ZFIN.::GO:0003190; P:atrioventricular valve formation; IMP:ZFIN.::GO:0001947; P:heart looping; IMP:ZFIN.::GO:0001756; P:somitogenesis; IMP:ZFIN. | 40 | Q96HC4 | 596 | PDLI5_HUMAN PDZ and LIM domain protein 5 OS=H... | 124 | 0.0000000004 | 67.8 | 31 | 47 | GO:0015629; C:actin cytoskeleton; IDA:LIFEdb.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0042805; F:actinin binding; ISS:UniProtKB.::GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB. | 41 | Q8K0Q5 | 663 | RHG18_MOUSE Rho GTPase-activating protein 18 ... | 211 | 0.000000000009 | 73.2 | 29 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 42 | Q62920 | 591 | PDLI5_RAT PDZ and LIM domain protein 5 OS=Rat... | 124 | 0.0000000007 | 66.6 | 31 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0042805; F:actinin binding; IDA:UniProtKB.::GO:0005080; F:protein kinase C binding; IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IMP:RGD.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; NAS:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; IDA:UniProtKB.::GO:0051963; P:regulation of synapse assembly; IDA:UniProtKB. | 43 | Q679P3 | 416 | PDLI7_CHICK PDZ and LIM domain protein 7 OS=G... | 118 | 0.000003 | 55.1 | 27 | 47 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW. | 44 | Q8CI51 | 591 | PDLI5_MOUSE PDZ and LIM domain protein 5 OS=M... | 124 | 0.0000000009 | 66.2 | 31 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB. | 45 | Q8N392 | 663 | RHG18_HUMAN Rho GTPase-activating protein 18 ... | 211 | 0.00000000003 | 71.2 | 29 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 46 | P48059 | 325 | LIMS1_HUMAN LIM and senescent cell antigen-li... | 146 | 0.00001 | 52.4 | 27 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0007569; P:cell aging; TAS:ProtInc.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB. | 47 | Q5FWK3 | 439 | RHG01_MOUSE Rho GTPase-activating protein 1 O... | 201 | 0.00000000005 | 70.1 | 27 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI. | | | | | | | | | | GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 48 | Q99JW4 | 325 | LIMS1_MOUSE LIM and senescent cell antigen-li... | 146 | 0.00002 | 52 | 27 | 45 | GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0007160; P:cell-matrix adhesion; IMP:MGI.::GO:0043009; P:chordate embryonic development; IMP:MGI.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI. | 49 | Q8QFP8 | 662 | LIMK1_CHICK LIM domain kinase 1 OS=Gallus gal... | 91 | 0.000000009 | 63.2 | 35 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 50 | O43182 | 974 | RHG06_HUMAN Rho GTPase-activating protein 6 O... | 216 | 0.0000000001 | 69.7 | 27 | 44 | GO:0005884; C:actin filament; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0016004; F:phospholipase activator activity; IDA:BHF-UCL.::GO:0043274; F:phospholipase binding; IPI:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0030041; P:actin filament polymerization; NAS:UniProtKB.::GO:0007202; P:activation of phospholipase C activity; IDA:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; IMP:BHF-UCL.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:BHF-UCL.::GO:0007266; P:Rho protein signal transduction; NAS:UniProtKB. | 51 | O54834 | 987 | RHG06_MOUSE Rho GTPase-activating protein 6 O... | 218 | 0.0000000001 | 69.7 | 28 | 43 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IDA:MGI.::GO:0048041; P:focal adhesion assembly; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 52 | A9LS46 | 690 | WTIP_XENLA Wilms tumor protein 1-interacting ... | 165 | 0.0000000001 | 69.3 | 28 | 45 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 53 | Q9VY77 | 728 | AJUBA_DROME LIM domain-containing protein jub... | 101 | 0.00002 | 52.4 | 25 | 44 | GO:0005912; C:adherens junction; IDA:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035329; P:hippo signaling cascade; IMP:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase. | 54 | Q7Z4I7 | 341 | LIMS2_HUMAN LIM and senescent cell antigen-li... | 176 | 0.006 | 43.9 | 24 | 41 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0034329; P:cell junction assembly; TAS:Reactome. | 55 | Q2KJ33 | 341 | LIMS2_BOVIN LIM and senescent cell antigen-li... | 176 | 0.004 | 44.7 | 24 | 40 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 56 | A8DZE6 | 648 | WTIP_DANRE Wilms tumor protein 1-interacting ... | 165 | 0.0000000003 | 68.2 | 28 | 45 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 57 | P53668 | 647 | LIMK1_MOUSE LIM domain kinase 1 OS=Mus muscul... | 92 | 0.0000007 | 57.4 | 30 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045773; P:positive regulation of axon extension; IGI:MGI. | 58 | Q69ZX8 | 682 | ABLM3_MOUSE Actin-binding LIM protein 3 OS=Mu... | 106 | 0.00005 | 51.2 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI. | 59 | P97447 | 280 | FHL1_MOUSE Four and a half LIM domains protei... | 183 | 0.044 | 40.8 | 22 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 60 | P20154 | 405 | LIN11_CAEEL Protein lin-11 OS=Caenorhabditis ... | 90 | 0.24 | 38.9 | 22 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007413; P:axonal fasciculation; IMP:WormBase.::GO:0001708; P:cell fate specification; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0045595; P:regulation of cell differentiation; IMP:WormBase.::GO:0030334; P:regulation of cell migration; IMP:WormBase. | 61 | Q9WUH4 | 280 | FHL1_RAT Four and a half LIM domains protein ... | 177 | 0.073 | 40.4 | 22 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. |
