| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
301 | Q6DFG0 | 1926 | RH21A_XENLA Rho GTPase-activating protein 21-... | 223 | 0.002 | 46.2 | 23 | 40 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 302 | Q8IRC7 | 275 | AWH_DROME LIM/homeobox protein Awh OS=Drosoph... | 125 | 0.002 | 45.1 | 24 | 39 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007444; P:imaginal disc development; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 303 | Q12979 | 859 | ABR_HUMAN Active breakpoint cluster region-re... | 186 | 0.002 | 45.8 | 25 | 41 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 304 | Q54C77 | 1186 | Y3184_DICDI Probable inactive serine/threonin... | 118 | 0.002 | 45.8 | 29 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 305 | Q8AVG0 | 862 | ABR_XENLA Active breakpoint cluster region-re... | 183 | 0.003 | 45.8 | 26 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 306 | P53405 | 349 | ISL1_DANRE Insulin gene enhancer protein isl-... | 121 | 0.007 | 43.5 | 25 | 40 | GO:0005634; C:nucleus; IDA:ZFIN. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0055011; P:atrial cardiac muscle cell differentiation; IMP:ZFIN.::GO:0031017; P:exocrine pancreas development; IMP:ZFIN.::GO:0048665; P:neuron fate specification; IMP:ZFIN.::GO:0048936; P:peripheral nervous system neuron axonogenesis; IMP:ZFIN. | 307 | Q2QLE3 | 421 | TES_PIG Testin OS=Sus scrofa (Pig). GN=TES ... | 110 | 0.27 | 38.9 | 24 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. | 308 | Q2QL92 | 421 | TES_MICMU Testin OS=Microcebus murinus (Lesse... | 110 | 1.1 | 37 | 24 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. | 309 | Q2QLB2 | 421 | TES_HORSE Testin OS=Equus caballus (Horse). G... | 110 | 0.45 | 38.1 | 24 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. | 310 | Q07E40 | 421 | TES_NEONE Testin OS=Neofelis nebulosa (Cloude... | 110 | 0.22 | 39.3 | 24 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. | 311 | Q640N3 | 1101 | RHG30_MOUSE Rho GTPase-activating protein 30 ... | 169 | 0.003 | 45.8 | 27 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 312 | A7YY57 | 1269 | RHG29_BOVIN Rho GTPase-activating protein 29 ... | 107 | 0.003 | 45.8 | 23 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 313 | Q108U9 | 421 | TES_LOXAF Testin OS=Loxodonta africana (Afric... | 110 | 0.27 | 38.9 | 24 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. | 314 | Q2IBH0 | 421 | TES_EULMM Testin OS=Eulemur macaco macaco (Bl... | 110 | 0.34 | 38.5 | 24 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. | 315 | Q3ZBI6 | 280 | FHL3_BOVIN Four and a half LIM domains protei... | 160 | 0.3 | 38.1 | 30 | 43 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 316 | P59281 | 1107 | RHG39_MOUSE Rho GTPase-activating protein 39 ... | 153 | 0.003 | 45.4 | 27 | 44 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 317 | Q5PQJ5 | 1266 | RHG29_RAT Rho GTPase-activating protein 29 OS... | 107 | 0.003 | 45.4 | 22 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 318 | Q61CA4 | 962 | SYD1_CAEBR Rho GTPase-activating protein syd-... | 111 | 0.004 | 45.4 | 25 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; ISS:UniProtKB. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 319 | A0M8S5 | 421 | TES_FELCA Testin OS=Felis catus (Cat) (Felis ... | 110 | 0.24 | 38.9 | 24 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. | 320 | P61374 | 349 | ISL1_RAT Insulin gene enhancer protein ISL-1 ... | 121 | 0.008 | 43.5 | 25 | 40 | GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0030331; F:estrogen receptor binding; IDA:BHF-UCL.::GO:0016922; F:ligand-dependent nuclear receptor binding; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031103; P:axon regeneration; IEP:RGD.::GO:0071385; P:cellular response to glucocorticoid stimulus; IEP:BHF-UCL.::GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IDA:BHF-UCL.::GO:0090074; P:negative regulation of protein homodimerization activity; IDA:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; IMP:RGD. | 321 | P61372 | 349 | ISL1_MOUSE Insulin gene enhancer protein ISL-... | 121 | 0.008 | 43.5 | 25 | 40 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060413; P:atrial septum morphogenesis; IGI:BHF-UCL.::GO:0060913; P:cardiac cell fate determination; IMP:MGI.::GO:0060379; P:cardiac muscle cell myoblast differentiation; IMP:MGI.::GO:0003215; P:cardiac right ventricle morphogenesis; IGI:BHF-UCL.::GO:0003203; P:endocardial cushion morphogenesis; IGI:BHF-UCL.::GO:0060384; P:innervation; IMP:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:BHF-UCL.::GO:0045665; P:negative regulation of neuron differentiation; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0001755; P:neural crest cell migration; IGI:MGI.::GO:0003148; P:outflow tract septum morphogenesis; IGI:BHF-UCL.::GO:0031016; P:pancreas development; IMP:MGI.::GO:0048936; P:peripheral nervous system neuron axonogenesis; IMP:BHF-UCL.::GO:0060037; P:pharyngeal system development; IGI:BHF-UCL.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.::GO:0043388; P:positive regulation of DNA binding; IDA:MGI.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:MGI.::GO:0003266; P:regulation of secondary heart field cardioblast proliferation; IMP:MGI.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:MGI.::GO:0048880; P:sensory system development; IMP:BHF-UCL.::GO:0021520; P:spinal cord motor neuron cell fate specification; IGI:MGI.::GO:0021559; P:trigeminal nerve development; IMP:BHF-UCL.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IGI:BHF-UCL.::GO:0021524; P:visceral motor neuron differentiation; IGI:MGI. | 322 | P61373 | 349 | ISL1_MESAU Insulin gene enhancer protein ISL-... | 121 | 0.008 | 43.5 | 25 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 323 | P61371 | 349 | ISL1_HUMAN Insulin gene enhancer protein ISL-... | 121 | 0.008 | 43.5 | 25 | 40 | GO:0005737; C:cytoplasm; NAS:BHF-UCL.::GO:0005634; C:nucleus; NAS:BHF-UCL. | | | | | | | | | | GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0001158; F:enhancer sequence-specific DNA binding; IDA:BHF-UCL.::GO:0030331; F:estrogen receptor binding; ISS:BHF-UCL.::GO:0016922; F:ligand-dependent nuclear receptor binding; ISS:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060413; P:atrial septum morphogenesis; ISS:BHF-UCL.::GO:0060913; P:cardiac cell fate determination; IDA:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.::GO:0071385; P:cellular response to glucocorticoid stimulus; ISS:BHF-UCL.::GO:0003203; P:endocardial cushion morphogenesis; ISS:BHF-UCL.::GO:0060384; P:innervation; ISS:BHF-UCL.::GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; ISS:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.::GO:0090074; P:negative regulation of protein homodimerization activity; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0003148; P:outflow tract septum morphogenesis; ISS:BHF-UCL.::GO:0031016; P:pancreas development; ISS:BHF-UCL.::GO:0048936; P:peripheral nervous system neuron axonogenesis; ISS:BHF-UCL.::GO:0060037; P:pharyngeal system development; ISS:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; IC:BHF-UCL.::GO:0003139; P:secondary heart field specification; IMP:BHF-UCL.::GO:0048880; P:sensory system development; ISS:BHF-UCL.::GO:0021559; P:trigeminal nerve development; ISS:BHF-UCL.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:BHF-UCL. | 324 | Q6INE5 | 507 | RHG19_XENLA Rho GTPase-activating protein 19 ... | 181 | 0.004 | 45.1 | 22 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 325 | Q8CGF1 | 1266 | RHG29_MOUSE Rho GTPase-activating protein 29 ... | 107 | 0.004 | 45.1 | 22 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 326 | B1AUC7 | 590 | RHG36_MOUSE Rho GTPase-activating protein 36 ... | 213 | 0.004 | 45.1 | 22 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 327 | Q07E51 | 421 | TES_DASNO Testin OS=Dasypus novemcinctus (Nin... | 110 | 0.094 | 40.4 | 25 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. | 328 | Q09YJ2 | 421 | TES_SHEEP Testin OS=Ovis aries (Sheep). GN=TE... | 110 | 0.25 | 38.9 | 24 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. | 329 | Q811P8 | 2089 | RHG32_MOUSE Rho GTPase-activating protein 32 ... | 231 | 0.005 | 45.1 | 23 | 39 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005938; C:cell cortex; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 330 | P46941 | 837 | TG325_CAEEL WW domain-containing protein tag-... | 189 | 0.005 | 44.7 | 20 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 331 | Q14192 | 279 | FHL2_HUMAN Four and a half LIM domains protei... | 95 | 9.9 | 33.5 | 25 | 43 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0009725; P:response to hormone stimulus; IMP:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
