Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Blastomyces dermatitidis LH 1408.1
Locus:
BDBG_00070
Length:
425
Number of sequences:
9555
Description:
C-3 sterol dehydrogenase/C-4 decarboxylase
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53199    349   ERG26_YEAST Sterol-4-alpha-carboxylate 3-dehy...4081e-54     191     33     50GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000252; F:C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC.
GO:0006696; P:ergosterol biosynthetic process; IDA:SGD.
2O43050    340   ERG26_SCHPO Sterol-4-alpha-carboxylate 3-dehy...3382e-49     177     33     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:PomBase.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000252; F:C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.
3Q3ZBE9    356   NSDHL_BOVIN Sterol-4-alpha-carboxylate 3-dehy...4009e-41     153     31     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
4Q9FX01    439   HSDD1_ARATH 3beta-hydroxysteroid-dehydrogenas...3178e-40     152     33     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IDA:TAIR.
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
5Q67ZE1    564   HSDD2_ARATH 3beta-hydroxysteroid-dehydrogenas...3349e-40     154     31     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IDA:TAIR.
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
6Q9R1J0    362   NSDHL_MOUSE Sterol-4-alpha-carboxylate 3-dehy...4009e-40     151     32     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0001942; P:hair follicle development; IMP:MGI.::GO:0060716; P:labyrinthine layer blood vessel development; IMP:MGI.::GO:0007224; P:smoothened signaling pathway; IGI:MGI.
7Q15738    373   NSDHL_HUMAN Sterol-4-alpha-carboxylate 3-dehy...4065e-36     140     29     44GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005811; C:lipid particle; IDA:UniProtKB.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
8Q5PPL3    362   NSDHL_RAT Sterol-4-alpha-carboxylate 3-dehydr...4007e-35     137     30     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
9A9X4U2    561   HSDD3_ARATH 3beta-hydroxysteroid-dehydrogenas...4086e-23     104     27     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC.
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
10Q8WUS8    393   D42E1_HUMAN Short-chain dehydrogenase/reducta...3302e-19     93.2     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
11Q4R7R1    393   D42E1_MACFA Short-chain dehydrogenase/reducta...3322e-19     92.8     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
12A8DZE7    387   D42E1_DANRE Short-chain dehydrogenase/reducta...3422e-19     92.8     27     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
13O53454    370   3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenas...4002e-19     92.4     27     43GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IDA:MTBBASE.::GO:0070403; F:NAD+ binding; IDA:MTBBASE.::GO:0004769; F:steroid delta-isomerase activity; IDA:MTBBASE.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; IDA:UniProtKB.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:InterPro.]
14Q32L94    393   D42E1_BOVIN Short-chain dehydrogenase/reducta...3371e-18     90.5     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
15Q9D665    394   D42E1_MOUSE Short-chain dehydrogenase/reducta...3352e-18     89.7     26     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
16Q0IH73    386   D42E1_XENLA Short-chain dehydrogenase/reducta...3360.0000000000003     74.7     26     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
17A6NKP2    422   D42E2_HUMAN Putative short-chain dehydrogenas...3380.0000000000004     74.3     25     42
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
18Q67477    370   3BHS_FOWPN 3 beta-hydroxysteroid dehydrogenas...4230.0000000000007     73.2     25     41
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
19Q64421    373   3BHS2_MESAU 3 beta-hydroxysteroid dehydrogena...4250.000000000004     70.9     25     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
20Q6GZS4    355   052L_FRG3G Uncharacterized protein 052L OS=Fr...4150.000000000004     70.9     26     39
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
21P26149    373   3BHS2_MOUSE 3 beta-hydroxysteroid dehydrogena...4200.000000000008     70.1     25     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
22O35469    373   3BHS6_MOUSE 3 beta-hydroxysteroid dehydrogena...4340.000000000008     70.1     24     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
23P26150    373   3BHS3_MOUSE 3 beta-hydroxysteroid dehydrogena...3310.000000000009     69.7     25     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
24Q60555    373   3BHS1_MESAU 3 beta-hydroxysteroid dehydrogena...4270.000000000009     69.7     24     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
25Q62878    373   3BHS4_RAT 3 beta-hydroxysteroid dehydrogenase...3340.00000000007     67     25     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IDA:RGD.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; TAS:RGD.
GO:0006702; P:androgen biosynthetic process; IDA:RGD.::GO:0006700; P:C21-steroid hormone biosynthetic process; IDA:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0034757; P:negative regulation of iron ion transport; IMP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0034698; P:response to gonadotropin stimulus; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.]
26P24815    373   3BHS1_MOUSE 3 beta-hydroxysteroid dehydrogena...4370.0000000001     66.6     22     38GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
27P22071    373   3BHS1_RAT 3 beta-hydroxysteroid dehydrogenase...3450.0000000004     64.7     25     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0030061; C:mitochondrial crista; IDA:RGD.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IDA:RGD.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD.::GO:0004769; F:steroid delta-isomerase activity; IDA:RGD.
GO:0030325; P:adrenal gland development; IEP:RGD.::GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0071549; P:cellular response to dexamethasone stimulus; IEP:RGD.::GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEP:RGD.::GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEP:RGD.::GO:0071333; P:cellular response to glucose stimulus; IEP:RGD.::GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071373; P:cellular response to luteinizing hormone stimulus; IEP:RGD.::GO:0071288; P:cellular response to mercury ion; IEP:RGD.::GO:0071406; P:cellular response to methylmercury; IEP:RGD.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:RGD.::GO:0018894; P:dibenzo-p-dioxin metabolic process; IEP:RGD.::GO:0016101; P:diterpenoid metabolic process; IEP:RGD.::GO:0006703; P:estrogen biosynthetic process; IEP:RGD.::GO:0008585; P:female gonad development; IEP:RGD.::GO:0050756; P:fractalkine metabolic process; IEP:RGD.::GO:0030851; P:granulocyte differentiation; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0017143; P:insecticide metabolic process; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0060135; P:maternal process involved in female pregnancy; IEP:RGD.::GO:0006082; P:organic acid metabolic process; IEP:RGD.::GO:0030728; P:ovulation; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0046470; P:phosphatidylcholine metabolic process; IEP:RGD.::GO:0006701; P:progesterone biosynthetic process; IDA:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0043279; P:response to alkaloid; IEP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0033591; P:response to L-ascorbic acid; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0061370; P:testosterone biosynthetic process; IEP:RGD.::GO:0018970; P:toluene metabolic process; IEP:RGD.
28O35296    373   3BHS3_MESAU 3 beta-hydroxysteroid dehydrogena...4290.0000000009     63.5     24     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
29P22072    373   3BHS2_RAT 3 beta-hydroxysteroid dehydrogenase...3340.000000002     62.8     24     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
30P26670    346   3BHS_VACCW 3 beta-hydroxysteroid dehydrogenas...4160.000000004     61.6     23     40
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
31P14060    373   3BHS1_HUMAN 3 beta-hydroxysteroid dehydrogena...4330.000000009     60.5     24     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB.::GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005758; C:mitochondrial intermembrane space; IDA:UniProtKB.::GO:0030868; C:smooth endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; ISS:UniProtKB.
GO:0006702; P:androgen biosynthetic process; TAS:UniProtKB.::GO:0006703; P:estrogen biosynthetic process; TAS:UniProtKB.::GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0006705; P:mineralocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
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