| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
541 | Q9Y2K2 | 1263 | SIK3_HUMAN Serine/threonine-protein kinase SI... | 139 | 0.0000006 | 58.9 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | | 542 | Q64702 | 925 | PLK4_MOUSE Serine/threonine-protein kinase PL... | 110 | 0.0000000006 | 68.6 | 33 | 53 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; IMP:UniProtKB. | 543 | Q95ZQ4 | 626 | AAPK2_CAEEL 5'-AMP-activated protein kinase c... | 146 | 0.005 | 45.4 | 28 | 45 | GO:0030424; C:axon; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:WormBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0061066; P:positive regulation of dauer larval development; IGI:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 544 | Q62833 | 590 | GRK5_RAT G protein-coupled receptor kinase 5 ... | 148 | 0.00000000004 | 72 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IC:RGD.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IMP:RGD.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 545 | Q8VEB1 | 590 | GRK5_MOUSE G protein-coupled receptor kinase ... | 145 | 0.00000000007 | 71.2 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 546 | Q60670 | 779 | SIK1_MOUSE Serine/threonine-protein kinase SI... | 165 | 0.001 | 47.8 | 24 | 43 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008140; F:cAMP response element binding protein binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0043276; P:anoikis; IMP:BHF-UCL.::GO:0055007; P:cardiac muscle cell differentiation; IMP:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0032792; P:negative regulation of CREB transcription factor activity; IDA:UniProtKB.::GO:0045721; P:negative regulation of gluconeogenesis; IDA:UniProtKB.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; IDA:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; IDA:UniProtKB.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB. | 547 | O61267 | 476 | LOK_DROME Ovarian-specific serine/threonine-p... | 92 | 0.00005 | 52 | 34 | 52 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0000077; P:DNA damage checkpoint; IDA:FlyBase.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:BHF-UCL.::GO:0007281; P:germ cell development; IEP:UniProtKB.::GO:0035234; P:germ cell programmed cell death; IMP:FlyBase.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:BHF-UCL. | 548 | Q9H093 | 628 | NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS... | 110 | 0.008 | 45.1 | 30 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB. | 549 | P50527 | 658 | STE20_SCHPO Serine/threonine-protein kinase s... | 111 | 0.0005 | 48.9 | 30 | 47 | GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0032488; P:Cdc42 protein signal transduction; IGI:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; TAS:PomBase.::GO:0061161; P:positive regulation of establishment of bipolar cell polarity regulating cell shape; IGI:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IGI:PomBase. | 550 | Q8CFH6 | 931 | SIK2_MOUSE Serine/threonine-protein kinase SI... | 110 | 0.0008 | 48.5 | 25 | 46 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; IDA:MGI.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; IDA:UniProtKB. | 551 | Q8T2I8 | 1167 | SEPA_DICDI Serine/threonine-protein kinase se... | 40 | 0.003 | 46.6 | 50 | 63 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 552 | O54748 | 491 | STK3_RAT Serine/threonine-protein kinase 3 OS... | 98 | 0.03 | 43.1 | 30 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 553 | Q3SWY6 | 426 | STK25_BOVIN Serine/threonine-protein kinase 2... | 53 | 0.043 | 42.4 | 42 | 49 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 554 | A2VDZ4 | 893 | PLK4_BOVIN Serine/threonine-protein kinase PL... | 101 | 0.0000000004 | 68.9 | 36 | 53 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB. | 555 | P54645 | 559 | AAPK1_RAT 5'-AMP-activated protein kinase cat... | 160 | 0.002 | 47 | 24 | 40 | GO:0031588; C:AMP-activated protein kinase complex; IDA:UniProtKB.::GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042557; F:eukaryotic elongation factor-2 kinase activator activity; NAS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0071361; P:cellular response to ethanol; IEP:RGD.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0071417; P:cellular response to organic nitrogen; IEP:RGD.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; IDA:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; NAS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:RGD.::GO:0046321; P:positive regulation of fatty acid oxidation; NAS:UniProtKB.::GO:0045722; P:positive regulation of gluconeogenesis; NAS:UniProtKB.::GO:0046326; P:positive regulation of glucose import; NAS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0060627; P:regulation of vesicle-mediated transport; IMP:RGD.::GO:0014823; P:response to activity; IDA:RGD.::GO:0031000; P:response to caffeine; IDA:RGD.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 556 | Q5EG47 | 559 | AAPK1_MOUSE 5'-AMP-activated protein kinase c... | 160 | 0.002 | 47 | 23 | 38 | GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0035174; F:histone serine kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0019395; P:fatty acid oxidation; IMP:MGI.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; IDA:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; IMP:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 557 | P08458 | 490 | SPS1_YEAST Sporulation-specific protein 1 OS=... | 89 | 0.0004 | 49.3 | 34 | 51 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005628; C:prospore membrane; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030476; P:ascospore wall assembly; IMP:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 558 | Q5RDH5 | 554 | AAPK1_PONAB 5'-AMP-activated protein kinase c... | 160 | 0.002 | 46.6 | 24 | 40 | GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 559 | O00506 | 426 | STK25_HUMAN Serine/threonine-protein kinase 2... | 53 | 0.04 | 42.4 | 42 | 49 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006979; P:response to oxidative stress; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc. | 560 | Q6ERS0 | 404 | CIPKR_ORYSJ Putative CBL-interacting protein ... | 93 | 0.018 | 43.5 | 33 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 561 | Q66HE5 | 630 | NUAK2_RAT NUAK family SNF1-like kinase 2 OS=R... | 109 | 0.013 | 44.3 | 30 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB. | 562 | Q13131 | 559 | AAPK1_HUMAN 5'-AMP-activated protein kinase c... | 160 | 0.002 | 46.6 | 24 | 40 | GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; NAS:UniProtKB.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; NAS:UniProtKB.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046318; P:negative regulation of glucosylceramide biosynthetic process; NAS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; NAS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045542; P:positive regulation of cholesterol biosynthetic process; NAS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; NAS:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 563 | Q9Z2W1 | 426 | STK25_MOUSE Serine/threonine-protein kinase 2... | 53 | 0.041 | 42.4 | 42 | 49 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.::GO:0051645; P:Golgi localization; IMP:MGI.::GO:0050772; P:positive regulation of axonogenesis; IMP:MGI. | 564 | O70126 | 345 | AURKB_MOUSE Aurora kinase B OS=Mus musculus (... | 115 | 0.00000000001 | 72 | 35 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 565 | O75011 | 652 | NAK1_SCHPO Serine/threonine-protein kinase na... | 47 | 0.04 | 42.7 | 43 | 57 | GO:0030479; C:actin cortical patch; TAS:PomBase.::GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0030037; P:actin filament reorganization involved in cell cycle; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0033554; P:cellular response to stress; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0010590; P:regulation of cytokinetic cell separation; IMP:PomBase.::GO:2000100; P:regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase. | 566 | Q8WTQ7 | 553 | GRK7_HUMAN G protein-coupled receptor kinase ... | 152 | 0.00001 | 53.9 | 28 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0050254; F:rhodopsin kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 567 | A4K2W5 | 487 | STK4_AOTNA Serine/threonine-protein kinase 4 ... | 40 | 0.027 | 43.1 | 43 | 63 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 568 | Q9H0K1 | 926 | SIK2_HUMAN Serine/threonine-protein kinase SI... | 110 | 0.001 | 47.8 | 25 | 46 | GO:0005794; C:Golgi apparatus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB. | 569 | Q6BVA0 | 412 | IPL1_DEBHA Spindle assembly checkpoint kinase... | 109 | 0.00000002 | 62.8 | 33 | 48 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 570 | Q7RZD3 | 954 | STE20_NEUCR Serine/threonine-protein kinase s... | 88 | 0.002 | 47 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 571 | O49717 | 554 | CDPKF_ARATH Calcium-dependent protein kinase ... | 111 | 0.00000003 | 62.8 | 32 | 51 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | |
