rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9Z0G2 | 565 | SRPK3_MOUSE SRSF protein kinase 3 OS=Mus musc... | 51 | 0.00002 | 48.9 | 47 | 71 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007519; P:skeletal muscle tissue development; IMP:MGI. | 2 | B8Y466 | 566 | SRPK3_PIG SRSF protein kinase 3 OS=Sus scrofa... | 51 | 0.00003 | 48.5 | 47 | 71 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0060537; P:muscle tissue development; ISS:UniProtKB. | 3 | P78362 | 688 | SRPK2_HUMAN SRSF protein kinase 2 OS=Homo sap... | 49 | 0.0001 | 46.6 | 45 | 67 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; ISS:BHF-UCL.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:BHF-UCL.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IC:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0045071; P:negative regulation of viral genome replication; IDA:BHF-UCL.::GO:0035063; P:nuclear speck organization; ISS:BHF-UCL.::GO:0045787; P:positive regulation of cell cycle; ISS:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.::GO:0010628; P:positive regulation of gene expression; ISS:BHF-UCL.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:BHF-UCL.::GO:0045070; P:positive regulation of viral genome replication; IDA:BHF-UCL.::GO:0048024; P:regulation of nuclear mRNA splicing, via spliceosome; TAS:UniProtKB.::GO:0000245; P:spliceosomal complex assembly; IDA:UniProtKB. | 4 | O54781 | 681 | SRPK2_MOUSE SRSF protein kinase 2 OS=Mus musc... | 49 | 0.0001 | 46.6 | 45 | 67 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IDA:BHF-UCL.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0045071; P:negative regulation of viral genome replication; ISS:BHF-UCL.::GO:0035063; P:nuclear speck organization; IDA:BHF-UCL.::GO:0045787; P:positive regulation of cell cycle; IDA:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.::GO:0010628; P:positive regulation of gene expression; IDA:BHF-UCL.::GO:0043525; P:positive regulation of neuron apoptotic process; IDA:BHF-UCL.::GO:0045070; P:positive regulation of viral genome replication; ISS:BHF-UCL.::GO:0000245; P:spliceosomal complex assembly; IDA:UniProtKB. | 5 | Q9UPE1 | 567 | SRPK3_HUMAN SRSF protein kinase 3 OS=Homo sap... | 51 | 0.0002 | 45.8 | 43 | 71 | | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. | 6 | Q45FA5 | 426 | SRPK_PHYPO Serine/threonine-protein kinase SR... | 47 | 0.0008 | 43.9 | 47 | 66 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | Q03656 | 742 | SKY1_YEAST Serine/threonine-protein kinase SK... | 44 | 0.0009 | 43.9 | 48 | 64 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0030003; P:cellular cation homeostasis; IMP:SGD.::GO:0006376; P:mRNA splice site selection; IGI:SGD.::GO:0042307; P:positive regulation of protein import into nucleus; IMP:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0042493; P:response to drug; IMP:SGD. | 8 | Q96SB4 | 655 | SRPK1_HUMAN SRSF protein kinase 1 OS=Homo sap... | 39 | 0.001 | 43.5 | 49 | 74 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007059; P:chromosome segregation; IDA:UniProtKB.::GO:0045087; P:innate immune response; IC:BHF-UCL.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0045071; P:negative regulation of viral genome replication; IDA:BHF-UCL.::GO:0045070; P:positive regulation of viral genome replication; IDA:BHF-UCL.::GO:0048024; P:regulation of nuclear mRNA splicing, via spliceosome; TAS:UniProtKB.::GO:0008380; P:RNA splicing; TAS:ProtInc.::GO:0035092; P:sperm chromatin condensation; TAS:UniProtKB. | 9 | Q5RD27 | 655 | SRPK1_PONAB SRSF protein kinase 1 OS=Pongo ab... | 39 | 0.001 | 43.5 | 49 | 74 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0050684; P:regulation of mRNA processing; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 10 | Q9V3I5 | 1207 | JIL1_DROME Chromosomal serine/threonine-prote... | 95 | 0.002 | 43.1 | 26 | 46 | GO:0000228; C:nuclear chromosome; IDA:UniProtKB.::GO:0005705; C:polytene chromosome interband; IDA:UniProtKB.::GO:0016456; C:X chromosome located dosage compensation complex, transcription activating; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0031936; P:negative regulation of chromatin silencing; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | O70551 | 648 | SRPK1_MOUSE SRSF protein kinase 1 OS=Mus musc... | 39 | 0.002 | 42.7 | 49 | 74 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0050684; P:regulation of mRNA processing; IDA:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 12 | Q61IS6 | 1132 | SPK1_CAEBR Serine/threonine-protein kinase sp... | 51 | 0.028 | 39.3 | 37 | 65 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; ISS:UniProtKB. | 13 | P36616 | 544 | DSK1_SCHPO Protein kinase dsk1 OS=Schizosacch... | 51 | 0.04 | 38.9 | 35 | 57 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; NAS:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.::GO:0048024; P:regulation of nuclear mRNA splicing, via spliceosome; IGI:PomBase. | 14 | Q03563 | 1003 | SPK1_CAEEL Serine/threonine-protein kinase sp... | 51 | 0.044 | 38.9 | 37 | 63 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IGI:UniProtKB.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase. | 15 | Q8NE28 | 680 | SGK71_HUMAN Protein kinase-like protein SgK07... | 108 | 0.075 | 38.1 | 26 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | | 16 | Q552C6 | 635 | ZAK2_DICDI Dual specificity protein kinase za... | 90 | 0.14 | 37 | 27 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0045860; P:positive regulation of protein kinase activity; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0042659; P:regulation of cell fate specification; IMP:dictyBase.::GO:0010468; P:regulation of gene expression; IDA:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 17 | Q9U1Y5 | 476 | CHK2_CAEEL Serine/threonine-protein kinase ch... | 93 | 0.17 | 36.6 | 28 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 18 | Q54WX4 | 384 | AURK_DICDI Aurora kinase OS=Dictyostelium dis... | 100 | 0.26 | 36.2 | 25 | 40 | GO:0005813; C:centrosome; IDA:dictyBase.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; IDA:dictyBase.::GO:0051233; C:spindle midzone; IDA:dictyBase.::GO:0000922; C:spindle pole; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000278; P:mitotic cell cycle; ISS:dictyBase. | 19 | P36005 | 433 | KDX1_YEAST Serine/threonine-protein kinase KD... | 139 | 0.6 | 35 | 23 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | Q08942 | 431 | NRKA_TRYBB Putative serine/threonine-protein ... | 121 | 0.69 | 34.7 | 21 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 21 | P22209 | 435 | KIN3_YEAST Serine/threonine-protein kinase KI... | 111 | 0.84 | 34.7 | 29 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007059; P:chromosome segregation; IMP:SGD. | 22 | Q95ZQ4 | 626 | AAPK2_CAEEL 5'-AMP-activated protein kinase c... | 45 | 0.91 | 34.7 | 36 | 58 | GO:0030424; C:axon; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:WormBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0061066; P:positive regulation of dauer larval development; IGI:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 23 | Q86A12 | 656 | SKY1_DICDI Probable serine/threonine-protein ... | 45 | 0.93 | 34.7 | 38 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | Q61532 | 720 | MK06_MOUSE Mitogen-activated protein kinase 6... | 211 | 0.96 | 34.7 | 24 | 39 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 25 | P38622 | 512 | RCK1_YEAST Serine/threonine-protein kinase RC... | 108 | 1 | 34.3 | 20 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0040020; P:regulation of meiosis; IMP:SGD. | 26 | Q54C77 | 1186 | Y3184_DICDI Probable inactive serine/threonin... | 91 | 1.1 | 34.3 | 29 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 27 | P13185 | 1064 | KIN1_YEAST Serine/threonine protein kinase KI... | 91 | 1.4 | 34.3 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:SGD. | 28 | Q5REX1 | 925 | SIK2_PONAB Serine/threonine-protein kinase SI... | 95 | 1.9 | 33.5 | 28 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB. | 29 | Q9H0K1 | 926 | SIK2_HUMAN Serine/threonine-protein kinase SI... | 95 | 2 | 33.5 | 28 | 45 | GO:0005794; C:Golgi apparatus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB. | 30 | Q75JK0 | 781 | ZAK1_DICDI Dual specificity protein kinase za... | 63 | 2 | 33.5 | 35 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IMP:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; IMP:UniProtKB.::GO:0001708; P:cell fate specification; IMP:UniProtKB.::GO:0033674; P:positive regulation of kinase activity; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0042659; P:regulation of cell fate specification; IMP:dictyBase.::GO:0061118; P:regulation of positive chemotaxis to cAMP; IMP:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 31 | Q6ZN16 | 1313 | M3K15_HUMAN Mitogen-activated protein kinase ... | 23 | 2.4 | 33.5 | 57 | 70 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | |