| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P48057 | 598 | SC6A1_MUSCO Sodium- and chloride-dependent GA... | 436 | 3e-50 | 189 | 31 | 50 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IEA:InterPro.::GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 2 | P30531 | 599 | SC6A1_HUMAN Sodium- and chloride-dependent GA... | 444 | 2e-49 | 186 | 31 | 50 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | GO:0007269; P:neurotransmitter secretion; TAS:Reactome. | 3 | P31646 | 602 | S6A13_RAT Sodium- and chloride-dependent GABA... | 442 | 4e-49 | 186 | 30 | 49 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IDA:RGD.::GO:0042165; F:neurotransmitter binding; IDA:RGD.::GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 4 | P23978 | 599 | SC6A1_RAT Sodium- and chloride-dependent GABA... | 437 | 1e-48 | 184 | 30 | 50 | GO:0009986; C:cell surface; IDA:RGD.::GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IDA:RGD.::GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0051939; P:gamma-aminobutyric acid import; IDA:RGD.::GO:0007612; P:learning; IMP:RGD.::GO:0032229; P:negative regulation of synaptic transmission, GABAergic; IMP:RGD.::GO:0014054; P:positive regulation of gamma-aminobutyric acid secretion; IMP:RGD.::GO:0051260; P:protein homooligomerization; IDA:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0042220; P:response to cocaine; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0014074; P:response to purine-containing compound; IMP:RGD.::GO:0009744; P:response to sucrose stimulus; IEP:RGD.::GO:0009636; P:response to toxin; IMP:RGD. | 5 | P31648 | 599 | SC6A1_MOUSE Sodium- and chloride-dependent GA... | 437 | 1e-48 | 184 | 30 | 50 | GO:0030424; C:axon; IDA:MGI.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 6 | A5PJX7 | 602 | S6A13_BOVIN Sodium- and chloride-dependent GA... | 445 | 2e-48 | 183 | 29 | 49 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IEA:InterPro.::GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 7 | Q9NSD5 | 602 | S6A13_HUMAN Sodium- and chloride-dependent GA... | 450 | 4e-48 | 182 | 29 | 48 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | GO:0007269; P:neurotransmitter secretion; TAS:Reactome. | 8 | P31649 | 602 | S6A13_MOUSE Sodium- and chloride-dependent GA... | 441 | 9e-48 | 182 | 29 | 48 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 9 | Q2PG55 | 609 | S6A13_MACFA Sodium- and chloride-dependent GA... | 442 | 5e-47 | 179 | 29 | 48 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IEA:InterPro.::GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 10 | P51905 | 622 | SC6A4_DROME Sodium-dependent serotonin transp... | 428 | 1e-46 | 178 | 31 | 49 | GO:0043679; C:axon terminus; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005261; F:cation channel activity; IDA:FlyBase.::GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.::GO:0015222; F:serotonin transmembrane transporter activity; IDA:FlyBase. | | | | | | | | | | GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0051610; P:serotonin uptake; IDA:FlyBase. | 11 | Q2A865 | 634 | S6A19_RAT Sodium-dependent neutral amino acid... | 492 | 1e-46 | 178 | 27 | 46 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | GO:0007584; P:response to nutrient; IEP:RGD. | 12 | Q62687 | 615 | S6A18_RAT Sodium-dependent neutral amino acid... | 496 | 1e-46 | 178 | 28 | 43 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.::GO:0006972; P:hyperosmotic response; IEP:RGD. | 13 | O88576 | 615 | S6A18_MOUSE Sodium-dependent neutral amino ac... | 496 | 2e-46 | 178 | 29 | 44 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | GO:0006865; P:amino acid transport; IEA:UniProtKB-KW. | 14 | Q9D687 | 634 | S6A19_MOUSE Sodium-dependent neutral amino ac... | 492 | 3e-46 | 177 | 27 | 46 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.::GO:0015175; F:neutral amino acid transmembrane transporter activity; IDA:MGI. | | | | | | | | | | | 15 | Q91502 | 611 | SC6A8_TORMA Creatine transporter OS=Torpedo m... | 455 | 4e-46 | 177 | 30 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 16 | Q5R6J1 | 634 | S6A19_PONAB Sodium-dependent neutral amino ac... | 500 | 5e-46 | 176 | 27 | 45 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | GO:0006865; P:amino acid transport; IEA:UniProtKB-KW. | 17 | Q695T7 | 634 | S6A19_HUMAN Sodium-dependent neutral amino ac... | 489 | 4e-45 | 174 | 27 | 44 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 18 | P48065 | 614 | S6A12_HUMAN Sodium- and chloride-dependent be... | 443 | 5e-45 | 173 | 29 | 49 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IEA:InterPro.::GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | GO:0007269; P:neurotransmitter secretion; TAS:Reactome. | 19 | Q96N87 | 628 | S6A18_HUMAN Sodium-dependent neutral amino ac... | 494 | 6e-45 | 173 | 29 | 45 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | GO:0006865; P:amino acid transport; TAS:Reactome. | 20 | P48055 | 614 | S6A12_RABIT Sodium- and chloride-dependent be... | 449 | 6e-45 | 173 | 29 | 48 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IEA:InterPro.::GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 21 | P31651 | 614 | S6A12_MOUSE Sodium- and chloride-dependent be... | 445 | 1e-44 | 172 | 29 | 49 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IEA:InterPro.::GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 22 | P48066 | 632 | S6A11_HUMAN Sodium- and chloride-dependent GA... | 453 | 2e-44 | 172 | 29 | 47 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | GO:0007269; P:neurotransmitter secretion; TAS:Reactome. | 23 | Q9XT49 | 630 | SC6A4_BOVIN Sodium-dependent serotonin transp... | 376 | 3e-44 | 171 | 29 | 49 | GO:0012505; C:endomembrane system; ISS:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0015222; F:serotonin transmembrane transporter activity; ISS:UniProtKB.::GO:0005335; F:serotonin:sodium symporter activity; ISS:UniProtKB. | | | | | | | | | | GO:0051259; P:protein oligomerization; ISS:UniProtKB.::GO:0051610; P:serotonin uptake; ISS:UniProtKB. | 24 | P31650 | 627 | S6A11_MOUSE Sodium- and chloride-dependent GA... | 454 | 3e-44 | 171 | 29 | 47 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | | 25 | Q9VR07 | 943 | INE_DROME Sodium- and chloride-dependent GABA... | 439 | 3e-44 | 174 | 27 | 49 | GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:FlyBase. | | | | | | | | | | GO:0005328; F:neurotransmitter:sodium symporter activity; ISS:FlyBase.::GO:0005034; F:osmosensor activity; IMP:UniProtKB.::GO:0009881; F:photoreceptor activity; IEA:InterPro. | | | | | | | | | | GO:0042066; P:perineurial glial growth; IGI:FlyBase.::GO:0047484; P:regulation of response to osmotic stress; IMP:UniProtKB.::GO:0019226; P:transmission of nerve impulse; IMP:UniProtKB. | 26 | P31647 | 627 | S6A11_RAT Sodium- and chloride-dependent GABA... | 454 | 4e-44 | 171 | 29 | 47 | GO:0042995; C:cell projection; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IDA:RGD.::GO:0042165; F:neurotransmitter binding; IDA:RGD.::GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD. | 27 | Q60857 | 630 | SC6A4_MOUSE Sodium-dependent serotonin transp... | 377 | 1e-43 | 169 | 29 | 49 | GO:0012505; C:endomembrane system; ISS:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0050998; F:nitric-oxide synthase binding; IPI:UniProtKB.::GO:0015222; F:serotonin transmembrane transporter activity; ISS:UniProtKB.::GO:0005335; F:serotonin:sodium symporter activity; ISS:UniProtKB. | | | | | | | | | | GO:0048854; P:brain morphogenesis; IMP:BHF-UCL.::GO:0046621; P:negative regulation of organ growth; IMP:BHF-UCL.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.::GO:0051610; P:serotonin uptake; IDA:UniProtKB.::GO:0035176; P:social behavior; IGI:BHF-UCL. | 28 | O35899 | 630 | SC6A4_CAVPO Sodium-dependent serotonin transp... | 449 | 4e-43 | 168 | 28 | 47 | GO:0012505; C:endomembrane system; ISS:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0015222; F:serotonin transmembrane transporter activity; ISS:UniProtKB.::GO:0005335; F:serotonin:sodium symporter activity; ISS:UniProtKB. | | | | | | | | | | GO:0051259; P:protein oligomerization; ISS:UniProtKB.::GO:0051610; P:serotonin uptake; ISS:UniProtKB. | 29 | P31652 | 630 | SC6A4_RAT Sodium-dependent serotonin transpor... | 377 | 5e-43 | 167 | 29 | 49 | GO:0012505; C:endomembrane system; IDA:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0019811; F:cocaine binding; IMP:RGD.::GO:0017022; F:myosin binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IMP:RGD.::GO:0015222; F:serotonin transmembrane transporter activity; IDA:UniProtKB.::GO:0005335; F:serotonin:sodium symporter activity; ISS:UniProtKB.::GO:0017075; F:syntaxin-1 binding; IPI:UniProtKB. | | | | | | | | | | GO:0071321; P:cellular response to cGMP; IDA:RGD.::GO:0071300; P:cellular response to retinoic acid; IEP:RGD.::GO:0007623; P:circadian rhythm; IMP:RGD.::GO:0007626; P:locomotory behavior; NAS:RGD.::GO:0007613; P:memory; IMP:RGD.::GO:0021941; P:negative regulation of cerebellar granule cell precursor proliferation; IMP:RGD.::GO:0045665; P:negative regulation of neuron differentiation; IMP:RGD.::GO:0032227; P:negative regulation of synaptic transmission, dopaminergic; IMP:RGD.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0051610; P:serotonin uptake; IDA:UniProtKB.::GO:0042713; P:sperm ejaculation; IMP:RGD.::GO:0042310; P:vasoconstriction; IMP:RGD. | 30 | Q9MYX0 | 630 | SC6A4_MACMU Sodium-dependent serotonin transp... | 377 | 1e-42 | 166 | 29 | 48 | GO:0012505; C:endomembrane system; ISS:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0015222; F:serotonin transmembrane transporter activity; ISS:UniProtKB.::GO:0005335; F:serotonin:sodium symporter activity; ISS:UniProtKB. | | | | | | | | | | GO:0051259; P:protein oligomerization; ISS:UniProtKB.::GO:0051610; P:serotonin uptake; ISS:UniProtKB. | 31 | P31645 | 630 | SC6A4_HUMAN Sodium-dependent serotonin transp... | 377 | 2e-42 | 166 | 29 | 48 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IDA:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0045121; C:membrane raft; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.::GO:0015222; F:serotonin transmembrane transporter activity; IDA:UniProtKB.::GO:0005335; F:serotonin:sodium symporter activity; IDA:UniProtKB. | | | | | | | | | | GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.::GO:0046621; P:negative regulation of organ growth; ISS:BHF-UCL.::GO:0009636; P:response to toxin; IDA:UniProtKB.::GO:0051610; P:serotonin uptake; IDA:UniProtKB.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0021794; P:thalamus development; IMP:UniProtKB. |
