rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
571 | Q91WL8 | 414 | WWOX_MOUSE WW domain-containing oxidoreductas... | 204 | 3.4 | 32.7 | 24 | 43 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 572 | P18297 | 262 | SPRE_RAT Sepiapterin reductase OS=Rattus norv... | 69 | 3.4 | 32.7 | 32 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0010033; P:response to organic substance; IMP:RGD.::GO:0006729; P:tetrahydrobiopterin biosynthetic process; IMP:RGD. | 573 | Q6PAY8 | 417 | HSDL2_XENLA Hydroxysteroid dehydrogenase-like... | 139 | 3.6 | 32.7 | 24 | 42 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 574 | P21898 | 254 | ADH_DROHE Alcohol dehydrogenase OS=Drosophila... | 180 | 3.9 | 32.3 | 27 | 41 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 575 | P15959 | 221 | NU6M_PODAN NADH-ubiquinone oxidoreductase cha... | 48 | 3.9 | 32.3 | 42 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:EC. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 576 | P35270 | 261 | SPRE_HUMAN Sepiapterin reductase OS=Homo sapi... | 69 | 4.1 | 32.3 | 30 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.::GO:0050661; F:NADP binding; TAS:UniProtKB.::GO:0004757; F:sepiapterin reductase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006809; P:nitric oxide biosynthetic process; IDA:UniProtKB.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006729; P:tetrahydrobiopterin biosynthetic process; TAS:UniProtKB. | 577 | Q8NK50 | 266 | DCXR_HYPJE L-xylulose reductase OS=Hypocrea j... | 185 | 4.2 | 32.3 | 22 | 42 | | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0005997; P:xylulose metabolic process; ISS:UniProtKB. | 578 | P25721 | 254 | ADH_DROMY Alcohol dehydrogenase OS=Drosophila... | 183 | 4.3 | 32.3 | 27 | 44 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 579 | Q9Y7P2 | 503 | YCKF_SCHPO Uncharacterized protein C1450.15 O... | 240 | 4.4 | 32.7 | 22 | 45 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016651; F:oxidoreductase activity, acting on NADH or NADPH; ISS:PomBase.::GO:0000234; F:phosphoethanolamine N-methyltransferase activity; ISS:PomBase. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; ISS:PomBase.::GO:0006506; P:GPI anchor biosynthetic process; ISS:PomBase. | 580 | P12854 | 254 | ADH1_DRONA Alcohol dehydrogenase 1 OS=Drosoph... | 254 | 5.2 | 32 | 24 | 39 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 581 | Q9JIF5 | 302 | PECR_CAVPO Peroxisomal trans-2-enoyl-CoA redu... | 107 | 6.5 | 32 | 24 | 46 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 582 | P42556 | 289 | PTR1_LEITA Pteridine reductase 1 OS=Leishmani... | 222 | 7.2 | 31.6 | 23 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047040; F:pteridine reductase activity; IEA:EC. | | | | | | | | | | GO:0031427; P:response to methotrexate; IEA:UniProtKB-KW. | 583 | P25720 | 254 | ADH2_DROBU Alcohol dehydrogenase 2 OS=Drosoph... | 183 | 7.5 | 31.6 | 27 | 43 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 584 | Q9ZMN7 | 275 | FABI_HELPJ Enoyl-[acyl-carrier-protein] reduc... | 146 | 7.7 | 31.6 | 18 | 49 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 585 | Q00669 | 254 | ADH_DROAD Alcohol dehydrogenase OS=Drosophila... | 110 | 8.4 | 31.2 | 29 | 44 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 586 | P0C0Y4 | 266 | MTDH_ALTAL Probable NADP-dependent mannitol d... | 192 | 8.8 | 31.2 | 24 | 42 | | | | | | | | | | | GO:0050085; F:mannitol 2-dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 587 | P0C0Y5 | 267 | MTDH_DAVTA Probable NADP-dependent mannitol d... | 202 | 8.8 | 31.2 | 26 | 42 | | | | | | | | | | | GO:0050085; F:mannitol 2-dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 588 | P73016 | 258 | FABI_SYNY3 Enoyl-[acyl-carrier-protein] reduc... | 196 | 9 | 31.2 | 20 | 40 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 589 | P23278 | 254 | ADH_DROSL Alcohol dehydrogenase OS=Drosophila... | 180 | 9.3 | 31.2 | 27 | 41 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 590 | P51660 | 735 | DHB4_MOUSE Peroxisomal multifunctional enzyme... | 208 | 9.6 | 31.6 | 24 | 42 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005777; C:peroxisome; IDA:MGI. | | | | | | | | | | GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; IEA:EC.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; IMP:MGI.::GO:0060009; P:Sertoli cell development; IMP:MGI.::GO:0000038; P:very long-chain fatty acid metabolic process; IMP:MGI. | 591 | P25988 | 254 | ADH_SCAAL Alcohol dehydrogenase OS=Scaptomyza... | 89 | 9.9 | 31.2 | 31 | 46 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. |