rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P50233 | 400 | DHI2_RAT Corticosteroid 11-beta-dehydrogenase... | 186 | 1e-18 | 88.2 | 32 | 50 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0007565; P:female pregnancy; IEP:RGD.::GO:0008211; P:glucocorticoid metabolic process; IDA:RGD.::GO:0002017; P:regulation of blood volume by renal aldosterone; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032094; P:response to food; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.] | 32 | O05730 | 284 | VDLC_HELPY Probable short-chain type dehydrog... | 275 | 2e-18 | 86.3 | 29 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 33 | P80365 | 405 | DHI2_HUMAN Corticosteroid 11-beta-dehydrogena... | 227 | 3e-18 | 87.4 | 30 | 46 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:ProtInc. | 34 | Q8VD48 | 319 | DHRS9_RAT Dehydrogenase/reductase SDR family ... | 192 | 3e-18 | 86.3 | 31 | 52 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; ISS:UniProtKB. | | | | | | | | | | GO:0042904; P:9-cis-retinoic acid biosynthetic process; ISS:UniProtKB. | 35 | O14756 | 317 | H17B6_HUMAN 17-beta-hydroxysteroid dehydrogen... | 212 | 4e-18 | 86.3 | 33 | 50 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0006702; P:androgen biosynthetic process; NAS:UniProtKB.::GO:0006710; P:androgen catabolic process; TAS:UniProtKB. | 36 | P51661 | 386 | DHI2_MOUSE Corticosteroid 11-beta-dehydrogena... | 186 | 4e-18 | 87 | 32 | 51 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 37 | Q9ZKW1 | 271 | VDLC_HELPJ Probable short-chain type dehydrog... | 270 | 4e-18 | 85.1 | 29 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | P37059 | 387 | DHB2_HUMAN Estradiol 17-beta-dehydrogenase 2 ... | 189 | 5e-18 | 86.7 | 34 | 53 | GO:0005789; C:endoplasmic reticulum membrane; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; TAS:BHF-UCL.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:UniProtKB. | | | | | | | | | | GO:0032526; P:response to retinoic acid; IDA:BHF-UCL. | 39 | O54753 | 317 | H17B6_RAT 17-beta-hydroxysteroid dehydrogenas... | 188 | 7e-18 | 85.1 | 36 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; TAS:RGD. | | | | | | | | | | GO:0008209; P:androgen metabolic process; TAS:RGD. | 40 | Q0VFE7 | 309 | DRS7B_XENTR Dehydrogenase/reductase SDR famil... | 192 | 1e-17 | 84.3 | 30 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 41 | Q27979 | 318 | RDH1_BOVIN 11-cis retinol dehydrogenase OS=Bo... | 184 | 1e-17 | 84.3 | 34 | 55 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 42 | Q937L4 | 250 | CPNA_COMTE Cyclopentanol dehydrogenase OS=Com... | 165 | 2e-17 | 83.2 | 34 | 52 | | | | | | | | | | | GO:0055041; F:cyclopentanol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 43 | Q8GAV9 | 250 | CPNA_COMS9 Cyclopentanol dehydrogenase OS=Com... | 165 | 2e-17 | 83.2 | 34 | 52 | | | | | | | | | | | GO:0055041; F:cyclopentanol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 44 | O75452 | 317 | RDH16_HUMAN Retinol dehydrogenase 16 OS=Homo ... | 187 | 2e-17 | 84 | 35 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; TAS:ProtInc. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0006629; P:lipid metabolic process; TAS:ProtInc. | 45 | P37959 | 280 | YUSZ_BACSU Uncharacterized oxidoreductase yus... | 188 | 3e-17 | 83.2 | 32 | 54 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 46 | P51976 | 406 | DHI2_RABIT Corticosteroid 11-beta-dehydrogena... | 186 | 3e-17 | 84.3 | 32 | 49 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 47 | P0AFP4 | 269 | YBBO_ECOLI Uncharacterized oxidoreductase ybb... | 181 | 4e-17 | 82.4 | 31 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 48 | P0AFP5 | 269 | YBBO_ECOL6 Uncharacterized oxidoreductase ybb... | 181 | 4e-17 | 82.4 | 31 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 49 | Q9Y394 | 339 | DHRS7_HUMAN Dehydrogenase/reductase SDR famil... | 191 | 4e-17 | 83.2 | 32 | 53 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 50 | Q05016 | 267 | YM71_YEAST Uncharacterized oxidoreductase YMR... | 203 | 5e-17 | 82 | 33 | 53 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IDA:SGD. | | | | | | | | | | | 51 | Q9X248 | 246 | FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] r... | 183 | 1e-16 | 80.5 | 36 | 51 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 52 | Q9KQH7 | 244 | FABG_VIBCH 3-oxoacyl-[acyl-carrier-protein] r... | 188 | 2e-16 | 80.5 | 30 | 54 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 53 | Q3T001 | 317 | H17B6_BOVIN 17-beta-hydroxysteroid dehydrogen... | 185 | 2e-16 | 81.3 | 36 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 54 | Q29529 | 244 | CBR2_PIG Carbonyl reductase [NADPH] 2 OS=Sus ... | 186 | 2e-16 | 79.7 | 32 | 53 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 55 | Q9Y140 | 326 | DHRS7_DROME Dehydrogenase/reductase SDR famil... | 271 | 3e-16 | 80.9 | 28 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 56 | P50168 | 427 | DHI2_SHEEP Corticosteroid 11-beta-dehydrogena... | 229 | 5e-16 | 81.3 | 30 | 47 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 57 | Q5ZJZ5 | 339 | BDH_CHICK D-beta-hydroxybutyrate dehydrogenas... | 197 | 5e-16 | 80.1 | 31 | 49 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 58 | Q8NEX9 | 313 | DR9C7_HUMAN Short-chain dehydrogenase/reducta... | 185 | 6e-16 | 79.7 | 33 | 53 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | | 59 | Q9R092 | 317 | H17B6_MOUSE 17-beta-hydroxysteroid dehydrogen... | 188 | 6e-16 | 79.7 | 37 | 53 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 60 | P05406 | 278 | FIXR_BRAJA Protein fixR OS=Bradyrhizobium jap... | 200 | 7e-16 | 79 | 30 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW. | 61 | Q3T0R4 | 325 | DRS7B_BOVIN Dehydrogenase/reductase SDR famil... | 192 | 0.000000000000001 | 79 | 29 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |