rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | P50164 | 260 | TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamu... | 187 | 0.00000000006 | 65.1 | 25 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050358; F:tropinone reductase activity; IEA:EC. | | | | | | | | | | | 152 | Q8JZV9 | 245 | BDH2_MOUSE 3-hydroxybutyrate dehydrogenase ty... | 207 | 0.00000000006 | 64.7 | 27 | 47 | GO:0005737; C:cytoplasm; ISS:HGNC. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; ISS:HGNC.::GO:0051287; F:NAD binding; ISS:HGNC.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IMP:UniProtKB. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; ISS:HGNC.::GO:0042168; P:heme metabolic process; ISS:UniProtKB.::GO:0055072; P:iron ion homeostasis; IMP:UniProtKB.::GO:0019290; P:siderophore biosynthetic process; IMP:UniProtKB. | 153 | Q9NYR8 | 311 | RDH8_HUMAN Retinol dehydrogenase 8 OS=Homo sa... | 190 | 0.00000000007 | 65.5 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:InterPro.::GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; TAS:ProtInc. | 154 | O18404 | 255 | HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase ty... | 200 | 0.00000000007 | 64.7 | 28 | 48 | GO:0005829; C:cytosol; NAS:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0047022; F:7-beta-hydroxysteroid dehydrogenase (NADP+) activity; IDA:FlyBase.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:FlyBase.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:FlyBase.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:FlyBase. | | | | | | | | | | GO:0006637; P:acyl-CoA metabolic process; IDA:FlyBase.::GO:0008209; P:androgen metabolic process; IDA:FlyBase.::GO:0008205; P:ecdysone metabolic process; IDA:FlyBase.::GO:0008210; P:estrogen metabolic process; IDA:FlyBase.::GO:0006631; P:fatty acid metabolic process; IDA:FlyBase.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 155 | A5E0R1 | 350 | MKAR_LODEL 3-ketoacyl-CoA reductase OS=NBRC 1... | 224 | 0.00000000007 | 65.5 | 27 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 156 | O57314 | 312 | DHB12_ANAPL Estradiol 17-beta-dehydrogenase 1... | 224 | 0.00000000008 | 65.5 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 157 | Q56632 | 262 | VIBA_VIBCH Vibriobactin-specific 2,3-dihydro-... | 187 | 0.00000000008 | 64.7 | 30 | 51 | | | | | | | | | | | GO:0008667; F:2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009239; P:enterobactin biosynthetic process; IEA:InterPro. | 158 | Q99714 | 261 | HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase ty... | 200 | 0.00000000009 | 64.3 | 29 | 49 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; EXP:Reactome.::GO:0008709; F:cholate 7-alpha-dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; TAS:Reactome.::GO:0006629; P:lipid metabolic process; TAS:ProtInc.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 159 | A7TMJ2 | 347 | MKAR_VANPO 3-ketoacyl-CoA reductase OS=(Kluyv... | 184 | 0.0000000001 | 65.1 | 28 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 160 | Q0U3N7 | 341 | MKAR_PHANO 3-ketoacyl-CoA reductase OS=(Glume... | 201 | 0.0000000001 | 65.1 | 27 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 161 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 215 | 0.0000000001 | 64.7 | 31 | 46 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 162 | A9UM79 | 311 | DRS7C_XENTR Dehydrogenase/reductase SDR famil... | 204 | 0.0000000001 | 64.7 | 23 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 163 | P28845 | 292 | DHI1_HUMAN Corticosteroid 11-beta-dehydrogena... | 179 | 0.0000000001 | 64.3 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.] | 164 | P14802 | 238 | YOXD_BACSU Uncharacterized oxidoreductase yox... | 131 | 0.0000000001 | 63.5 | 34 | 54 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 165 | Q6P3L6 | 319 | DH12A_DANRE Estradiol 17-beta-dehydrogenase 1... | 217 | 0.0000000002 | 64.3 | 27 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 166 | Q6NUE2 | 236 | CBR4_XENLA Carbonyl reductase family member 4... | 182 | 0.0000000002 | 63.2 | 26 | 48 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 167 | A6RBW9 | 339 | MKAR_AJECN 3-ketoacyl-CoA reductase OS=(Histo... | 211 | 0.0000000002 | 64.3 | 27 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 168 | Q5XG41 | 318 | DH12A_XENLA Estradiol 17-beta-dehydrogenase 1... | 192 | 0.0000000002 | 64.3 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 169 | P19337 | 249 | BAIA2_EUBSP Bile acid 7-dehydroxylase 2 OS=Eu... | 187 | 0.0000000002 | 63.2 | 32 | 52 | | | | | | | | | | | GO:0033792; F:bile-acid 7alpha-dehydroxylase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 170 | P00335 | 249 | RIDH_ENTAE Ribitol 2-dehydrogenase OS=Enterob... | 225 | 0.0000000002 | 63.2 | 28 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050255; F:ribitol 2-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 171 | Q56318 | 256 | Y019_THEMA Uncharacterized oxidoreductase TM_... | 174 | 0.0000000002 | 63.2 | 26 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 172 | Q28IU1 | 320 | DHB12_XENTR Estradiol 17-beta-dehydrogenase 1... | 192 | 0.0000000003 | 63.9 | 27 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 173 | P50842 | 254 | KDUD_BACSU 2-dehydro-3-deoxy-D-gluconate 5-de... | 204 | 0.0000000003 | 63.2 | 27 | 49 | | | | | | | | | | | GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 174 | P50165 | 268 | TRNH_DATST Tropinone reductase homolog OS=Dat... | 194 | 0.0000000003 | 63.2 | 28 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 175 | Q8AVY8 | 318 | DH12B_XENLA Estradiol 17-beta-dehydrogenase 1... | 192 | 0.0000000003 | 63.5 | 26 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 176 | P16232 | 288 | DHI1_RAT Corticosteroid 11-beta-dehydrogenase... | 205 | 0.0000000003 | 63.2 | 28 | 43 | GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0071392; P:cellular response to estradiol stimulus; IEP:RGD.::GO:0006704; P:glucocorticoid biosynthetic process; IDA:RGD.::GO:0006713; P:glucocorticoid catabolic process; IDA:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0043456; P:regulation of pentose-phosphate shunt; IDA:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.] | 177 | P39577 | 252 | DLTE_BACSU Uncharacterized oxidoreductase dlt... | 189 | 0.0000000003 | 62.8 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 178 | P40288 | 261 | DHG_BACME Glucose 1-dehydrogenase OS=Bacillus... | 187 | 0.0000000004 | 62.8 | 29 | 49 | | | | | | | | | | | GO:0047936; F:glucose 1-dehydrogenase [NAD(P) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.] | 179 | Q920P0 | 244 | DCXR_RAT L-xylulose reductase OS=Rattus norve... | 184 | 0.0000000004 | 62.4 | 28 | 48 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 180 | P37079 | 267 | SORD_KLEPN Sorbitol-6-phosphate 2-dehydrogena... | 205 | 0.0000000004 | 62.8 | 24 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0009010; F:sorbitol-6-phosphate 2-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 181 | A4IFA7 | 237 | CBR4_BOVIN Carbonyl reductase family member 4... | 186 | 0.0000000004 | 62 | 25 | 48 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. |