| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O29627 | 326 | LEU3_ARCFU 3-isopropylmalate dehydrogenase OS... | 340 | 2e-82 | 260 | 43 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 2 | Q945K7 | 374 | IDH5_ARATH Isocitrate dehydrogenase [NAD] cat... | 337 | 5e-78 | 250 | 40 | 58 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:TAIR.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:TAIR.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:TAIR. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; IMP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 3 | Q8LG77 | 374 | IDH6_ARATH Isocitrate dehydrogenase [NAD] cat... | 341 | 4e-77 | 248 | 41 | 56 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 4 | Q58991 | 347 | AKSF_METJA Homoisocitrate dehydrogenase OS=JC... | 360 | 7e-77 | 246 | 41 | 58 | | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:InterPro.::GO:0047046; F:homoisocitrate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:InterPro. | 5 | Q9VWH4 | 377 | IDH3A_DROME Probable isocitrate dehydrogenase... | 343 | 2e-74 | 241 | 36 | 57 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; ISS:UniProtKB. | 6 | Q55BI2 | 354 | IDHA_DICDI Isocitrate dehydrogenase [NAD] reg... | 340 | 3e-73 | 237 | 38 | 56 | GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 7 | Q93714 | 358 | IDH3A_CAEEL Probable isocitrate dehydrogenase... | 344 | 9e-73 | 236 | 38 | 56 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 8 | Q54B68 | 360 | IDHB_DICDI Isocitrate dehydrogenase [NAD] reg... | 341 | 3e-71 | 232 | 38 | 59 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 9 | O27441 | 329 | LEU3_METTH 3-isopropylmalate dehydrogenase OS... | 341 | 4e-71 | 231 | 38 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 10 | Q58130 | 333 | LEU3_METJA 3-isopropylmalate/3-methylmalate d... | 348 | 3e-69 | 226 | 40 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0046553; F:D-malate dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 11 | P41563 | 366 | IDH3A_BOVIN Isocitrate dehydrogenase [NAD] su... | 346 | 2e-68 | 225 | 37 | 56 | GO:0005739; C:mitochondrion; ISS:AgBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 12 | P29696 | 357 | LEU3_SOLTU 3-isopropylmalate dehydrogenase, c... | 322 | 5e-68 | 224 | 37 | 57 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro. | 13 | Q9D6R2 | 366 | IDH3A_MOUSE Isocitrate dehydrogenase [NAD] su... | 346 | 7e-67 | 221 | 36 | 56 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 14 | Q99NA5 | 366 | IDH3A_RAT Isocitrate dehydrogenase [NAD] subu... | 346 | 4e-66 | 219 | 36 | 55 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. | 15 | P50213 | 366 | IDH3A_HUMAN Isocitrate dehydrogenase [NAD] su... | 346 | 9e-66 | 218 | 36 | 55 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 16 | Q5R678 | 366 | IDH3A_PONAB Isocitrate dehydrogenase [NAD] su... | 346 | 1e-65 | 218 | 36 | 55 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 17 | Q9USP8 | 378 | IDH2_SCHPO Isocitrate dehydrogenase [NAD] sub... | 349 | 2e-65 | 218 | 36 | 54 | GO:0005759; C:mitochondrial matrix; ISS:PomBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; IMP:PomBase.::GO:0006102; P:isocitrate metabolic process; IMP:PomBase.::GO:0006099; P:tricarboxylic acid cycle; IMP:PomBase. | 18 | Q28480 | 347 | IDH3A_MACFA Isocitrate dehydrogenase [NAD] su... | 348 | 2e-65 | 216 | 36 | 55 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 19 | Q8LFC0 | 367 | IDH1_ARATH Isocitrate dehydrogenase [NAD] reg... | 344 | 2e-65 | 217 | 37 | 57 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:TAIR. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; IMP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 20 | P93032 | 367 | IDH2_ARATH Isocitrate dehydrogenase [NAD] reg... | 346 | 6e-65 | 216 | 37 | 57 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 21 | P28241 | 369 | IDH2_YEAST Isocitrate dehydrogenase [NAD] sub... | 345 | 3e-63 | 211 | 37 | 54 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IDA:SGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; TAS:SGD. | 22 | P50455 | 337 | LEU3_SULTO 3-isopropylmalate dehydrogenase OS... | 349 | 6e-63 | 210 | 37 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 23 | Q9UXB2 | 336 | LEU3_SULSO 3-isopropylmalate dehydrogenase OS... | 351 | 2e-62 | 209 | 37 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 24 | O81796 | 368 | IDH3_ARATH Isocitrate dehydrogenase [NAD] reg... | 344 | 6e-61 | 206 | 35 | 57 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IGI:TAIR.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; IGI:TAIR.::GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 25 | O14104 | 362 | LYS12_SCHPO Probable homoisocitrate dehydroge... | 360 | 6e-60 | 203 | 37 | 54 | GO:0005739; C:mitochondrion; ISS:PomBase. | | | | | | | | | | GO:0047046; F:homoisocitrate dehydrogenase activity; ISS:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0009085; P:lysine biosynthetic process; IMP:PomBase. | 26 | P40495 | 371 | LYS12_YEAST Homoisocitrate dehydrogenase, mit... | 356 | 9e-60 | 202 | 37 | 55 | GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0047046; F:homoisocitrate dehydrogenase activity; IDA:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW. | 27 | O94230 | 368 | IDH2_KLULA Isocitrate dehydrogenase [NAD] sub... | 345 | 3e-59 | 201 | 36 | 53 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 28 | Q1RJU4 | 483 | IDH_RICBR Isocitrate dehydrogenase [NADP] OS=... | 320 | 5e-58 | 201 | 37 | 55 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 29 | Q9ZDR0 | 483 | IDH_RICPR Isocitrate dehydrogenase [NADP] OS=... | 351 | 3e-57 | 199 | 35 | 53 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 30 | O13302 | 388 | IDH1_AJECA Isocitrate dehydrogenase [NAD] sub... | 340 | 3e-57 | 196 | 34 | 54 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 31 | Q93353 | 379 | IDH3B_CAEEL Probable isocitrate dehydrogenase... | 343 | 6e-57 | 195 | 35 | 55 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. |
