rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q93353 | 379 | IDH3B_CAEEL Probable isocitrate dehydrogenase... | 343 | 6e-57 | 195 | 35 | 55 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 32 | P33197 | 496 | IDH_THET8 Isocitrate dehydrogenase [NADP] OS=... | 332 | 1e-56 | 197 | 35 | 54 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 33 | Q68XA5 | 483 | IDH_RICTY Isocitrate dehydrogenase [NADP] OS=... | 320 | 6e-56 | 195 | 36 | 54 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 34 | O13696 | 356 | IDH1_SCHPO Isocitrate dehydrogenase [NAD] sub... | 341 | 2e-55 | 191 | 35 | 52 | GO:0005759; C:mitochondrial matrix; ISS:PomBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; IMP:PomBase.::GO:0006102; P:isocitrate metabolic process; IMP:PomBase.::GO:0006099; P:tricarboxylic acid cycle; IMP:PomBase. | 35 | Q4UKR1 | 483 | IDH_RICFE Isocitrate dehydrogenase [NADP] OS=... | 320 | 9e-55 | 192 | 36 | 54 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 36 | O77784 | 385 | IDH3B_BOVIN Isocitrate dehydrogenase [NAD] su... | 350 | 1e-54 | 189 | 35 | 55 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 37 | P61495 | 345 | LEU3_THETH 3-isopropylmalate dehydrogenase OS... | 346 | 1e-54 | 188 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 38 | Q5SIY4 | 345 | LEU3_THET8 3-isopropylmalate dehydrogenase OS... | 346 | 5e-54 | 187 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 39 | Q28479 | 385 | IDH3B_MACFA Isocitrate dehydrogenase [NAD] su... | 350 | 7e-54 | 187 | 35 | 55 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 40 | Q68FX0 | 385 | IDH3B_RAT Isocitrate dehydrogenase [NAD] subu... | 350 | 1e-53 | 187 | 35 | 54 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. | 41 | O43837 | 385 | IDH3B_HUMAN Isocitrate dehydrogenase [NAD] su... | 350 | 2e-53 | 186 | 35 | 55 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; TAS:ProtInc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; TAS:ProtInc.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 42 | P61494 | 345 | LEU3_THET2 3-isopropylmalate dehydrogenase OS... | 347 | 2e-53 | 185 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 43 | Q92IR7 | 483 | IDH_RICCN Isocitrate dehydrogenase [NADP] OS=... | 336 | 2e-52 | 186 | 35 | 52 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 44 | O94229 | 361 | IDH1_KLULA Isocitrate dehydrogenase [NAD] sub... | 340 | 2e-52 | 183 | 32 | 53 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 45 | P24098 | 344 | LEU3_THEAQ 3-isopropylmalate dehydrogenase OS... | 352 | 3e-52 | 182 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 46 | Q5RBT4 | 385 | IDH3B_PONAB Isocitrate dehydrogenase [NAD] su... | 350 | 9e-52 | 182 | 35 | 54 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 47 | P70404 | 393 | IDHG1_MOUSE Isocitrate dehydrogenase [NAD] su... | 349 | 4e-50 | 177 | 32 | 53 | GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 48 | Q02143 | 345 | LEU3_LACLA 3-isopropylmalate dehydrogenase OS... | 366 | 4e-50 | 176 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 49 | Q2G4X5 | 352 | LEU3_NOVAD 3-isopropylmalate dehydrogenase OS... | 365 | 6e-50 | 176 | 37 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 50 | P41565 | 393 | IDHG1_RAT Isocitrate dehydrogenase [NAD] subu... | 349 | 8e-50 | 177 | 32 | 52 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0045926; P:negative regulation of growth; IMP:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. | 51 | P41564 | 355 | IDH3G_MACFA Isocitrate dehydrogenase [NAD] su... | 349 | 9e-50 | 176 | 32 | 53 | GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 52 | P51553 | 393 | IDH3G_HUMAN Isocitrate dehydrogenase [NAD] su... | 348 | 5e-49 | 174 | 31 | 52 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 53 | Q9WZ26 | 354 | LEU3_THEMA 3-isopropylmalate dehydrogenase OS... | 367 | 6e-49 | 173 | 36 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 54 | Q58CP0 | 392 | IDH3G_BOVIN Isocitrate dehydrogenase [NAD] su... | 348 | 7e-49 | 174 | 32 | 51 | GO:0005739; C:mitochondrion; ISS:AgBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 55 | Q5M405 | 345 | LEU3_STRT2 3-isopropylmalate dehydrogenase OS... | 359 | 2e-48 | 172 | 36 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 56 | Q5LZF3 | 345 | LEU3_STRT1 3-isopropylmalate dehydrogenase OS... | 359 | 2e-48 | 172 | 36 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 57 | Q5NPQ9 | 349 | LEU3_ZYMMO 3-isopropylmalate dehydrogenase OS... | 354 | 2e-48 | 172 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 58 | Q8DTG3 | 344 | LEU3_STRMU 3-isopropylmalate dehydrogenase OS... | 353 | 2e-48 | 172 | 37 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 59 | Q8BPC6 | 396 | IDHG2_MOUSE Probable isocitrate dehydrogenase... | 339 | 5e-48 | 172 | 30 | 52 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 60 | Q4QQT5 | 395 | IDHG2_RAT Probable isocitrate dehydrogenase [... | 339 | 6e-48 | 172 | 32 | 52 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 61 | Q5F8T6 | 356 | LEU3_NEIG1 3-isopropylmalate dehydrogenase OS... | 338 | 2e-47 | 169 | 35 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. |