| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9FG65 | 502 | C81D1_ARATH Cytochrome P450 81D1 OS=Arabidops... | 76 | 0.028 | 38.1 | 30 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 32 | P17178 | 533 | CP27A_RAT Sterol 26-hydroxylase, mitochondria... | 70 | 0.029 | 38.1 | 27 | 54 | | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0031073; F:cholesterol 26-hydroxylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IDA:RGD.::GO:0006706; P:steroid catabolic process; TAS:RGD. | 33 | Q9M066 | 524 | C90C1_ARATH 3-epi-6-deoxocathasterone 23-mono... | 90 | 0.029 | 38.1 | 23 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IDA:TAIR. | | | | | | | | | | GO:0016132; P:brassinosteroid biosynthetic process; IMP:TAIR.::GO:0010268; P:brassinosteroid homeostasis; IEP:TAIR.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0042814; P:monopolar cell growth; IMP:TAIR.::GO:0048441; P:petal development; IGI:TAIR.::GO:0048443; P:stamen development; IGI:TAIR. | 34 | Q949P1 | 467 | ABAH1_ARATH Abscisic acid 8'-hydroxylase 1 OS... | 72 | 0.029 | 38.1 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009687; P:abscisic acid metabolic process; IMP:TAIR.::GO:0050832; P:defense response to fungus; IEP:TAIR.::GO:0048838; P:release of seed from dormancy; IMP:TAIR.::GO:0009639; P:response to red or far red light; IEP:TAIR. | 35 | O64698 | 499 | C7102_ARATH Cytochrome P450 710A2 OS=Arabidop... | 68 | 0.033 | 37.7 | 32 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 36 | Q7YRB2 | 501 | CP8B1_PIG 5-beta-cholestane-3-alpha,7-alpha-d... | 80 | 0.034 | 37.7 | 23 | 54 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033779; F:5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 37 | Q9V4U9 | 493 | C6A13_DROME Probable cytochrome P450 6a13 OS=... | 75 | 0.037 | 37.7 | 32 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 38 | Q02318 | 531 | CP27A_HUMAN Sterol 26-hydroxylase, mitochondr... | 99 | 0.039 | 37.7 | 25 | 51 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 39 | Q55EK2 | 532 | C524A_DICDI Probable cytochrome P450 524A1 OS... | 61 | 0.041 | 37.7 | 30 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 40 | Q92109 | 522 | CP1A3_ONCMY Cytochrome P450 1A3 OS=Oncorhynch... | 72 | 0.047 | 37.4 | 31 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 41 | Q29626 | 500 | PTGIS_BOVIN Prostacyclin synthase OS=Bos taur... | 76 | 0.048 | 37.4 | 28 | 47 | GO:0005901; C:caveola; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0008116; F:prostaglandin-I synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0071354; P:cellular response to interleukin-6; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045019; P:negative regulation of nitric oxide biosynthetic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; ISS:UniProtKB.::GO:0001516; P:prostaglandin biosynthetic process; ISS:UniProtKB. | 42 | Q9ZV28 | 493 | C7104_ARATH Cytochrome P450 710A1 OS=Arabidop... | 72 | 0.048 | 37.4 | 32 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 43 | P15129 | 511 | CP4B1_RAT Cytochrome P450 4B1 OS=Rattus norve... | 82 | 0.056 | 37.4 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0008144; F:drug binding; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0018585; F:fluorene oxygenase activity; IDA:RGD.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0018879; P:biphenyl metabolic process; IMP:RGD.::GO:0042738; P:exogenous drug catabolic process; IDA:RGD.::GO:0018917; P:fluorene metabolic process; IDA:RGD. | 44 | P13584 | 511 | CP4B1_HUMAN Cytochrome P450 4B1 OS=Homo sapie... | 82 | 0.056 | 37.4 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 45 | O02766 | 500 | CP8B1_RABIT 7-alpha-hydroxycholest-4-en-3-one... | 94 | 0.059 | 37 | 30 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033778; F:7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 46 | Q9DBG1 | 533 | CP27A_MOUSE Sterol 26-hydroxylase, mitochondr... | 71 | 0.072 | 37 | 27 | 51 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 47 | Q9CX98 | 530 | CP2U1_MOUSE Cytochrome P450 2U1 OS=Mus muscul... | 150 | 0.075 | 37 | 24 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 48 | Q9HCS2 | 524 | CP4FC_HUMAN Cytochrome P450 4F12 OS=Homo sapi... | 84 | 0.085 | 36.6 | 21 | 49 | GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; ISS:UniProtKB.::GO:0008392; F:arachidonic acid epoxygenase activity; ISS:UniProtKB.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; ISS:UniProtKB.::GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; ISS:UniProtKB. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0019373; P:epoxygenase P450 pathway; ISS:UniProtKB.::GO:0030195; P:negative regulation of blood coagulation; ISS:UniProtKB.::GO:0003095; P:pressure natriuresis; ISS:UniProtKB.::GO:0003091; P:renal water homeostasis; ISS:UniProtKB.::GO:0055078; P:sodium ion homeostasis; ISS:UniProtKB.::GO:0042360; P:vitamin E metabolic process; ISS:UniProtKB.::GO:0042371; P:vitamin K biosynthetic process; ISS:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 49 | P22680 | 504 | CP7A1_HUMAN Cholesterol 7-alpha-monooxygenase... | 83 | 0.086 | 36.6 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 50 | O23976 | 490 | C76B1_HELTU 7-ethoxycoumarin O-deethylase OS=... | 101 | 0.1 | 36.6 | 25 | 43 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 51 | P98181 | 515 | CP1A1_PAGMA Cytochrome P450 1A1 OS=Pagrus maj... | 76 | 0.11 | 36.2 | 30 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 52 | O49859 | 525 | C82A4_SOYBN Cytochrome P450 82A4 OS=Glycine m... | 74 | 0.11 | 36.2 | 30 | 46 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 53 | Q947B7 | 493 | MFS_MENPI (+)-menthofuran synthase OS=Mentha ... | 96 | 0.12 | 36.2 | 26 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0052582; F:(+)-menthofuran synthase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006721; P:terpenoid metabolic process; IDA:UniProtKB. | 54 | P93147 | 499 | C81E1_GLYEC Isoflavone 2'-hydroxylase OS=Glyc... | 90 | 0.12 | 36.2 | 30 | 46 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033773; F:isoflavone 2'-hydroxylase activity; IEA:EC. | | | | | | | | | | | 55 | Q9LZ31 | 512 | C77A4_ARATH Cytochrome P450 77A4 OS=Arabidops... | 76 | 0.13 | 36.2 | 26 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0019395; P:fatty acid oxidation; IDA:UniProtKB. | 56 | Q6VVX0 | 501 | CP2R1_HUMAN Vitamin D 25-hydroxylase OS=Homo ... | 82 | 0.13 | 36.2 | 26 | 40 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0042359; P:vitamin D metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 57 | Q29496 | 503 | CP3AO_SHEEP Cytochrome P450 3A24 OS=Ovis arie... | 107 | 0.13 | 36.2 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 58 | Q43257 | 538 | C71C4_MAIZE indole-2-monooxygenase OS=Zea may... | 98 | 0.14 | 36.2 | 30 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 59 | P47787 | 534 | THAS_PIG Thromboxane-A synthase OS=Sus scrofa... | 110 | 0.14 | 36.2 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0004796; F:thromboxane-A synthase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 60 | O75881 | 506 | CP7B1_HUMAN 25-hydroxycholesterol 7-alpha-hyd... | 67 | 0.15 | 35.8 | 34 | 52 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033783; F:25-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; TAS:ProtInc. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 61 | P24464 | 508 | CP4AC_RAT Cytochrome P450 4A12 OS=Rattus norv... | 79 | 0.16 | 35.8 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD. |
