| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O35625 | 863 | AXIN1_MOUSE Axin-1 OS=Mus musculus (Mouse). G... | 40 | 0.39 | 32 | 40 | 60 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:MGI.::GO:0005938; C:cell cortex; IDA:MGI.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005881; C:cytoplasmic microtubule; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0044459; C:plasma membrane part; IDA:MGI.::GO:0014069; C:postsynaptic density; IBA:RefGenome.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0070016; F:armadillo repeat domain binding; IBA:RefGenome.::GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0005096; F:GTPase activator activity; IBA:RefGenome.::GO:0070411; F:I-SMAD binding; IDA:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IDA:MGI.::GO:0032947; F:protein complex scaffold; IMP:BHF-UCL.::GO:0019904; F:protein domain specific binding; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:MGI.::GO:0043621; F:protein self-association; IPI:MGI.::GO:0070412; F:R-SMAD binding; IPI:MGI.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IBA:RefGenome.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048320; P:axial mesoderm formation; IMP:MGI.::GO:0060823; P:canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation; IBA:RefGenome.::GO:0008219; P:cell death; IBA:RefGenome.::GO:0071407; P:cellular response to organic cyclic compound; IBA:RefGenome.::GO:0031122; P:cytoplasmic microtubule organization; IGI:MGI.::GO:0007368; P:determination of left/right symmetry; IBA:RefGenome.::GO:0009950; P:dorsal/ventral axis specification; IDA:MGI.::GO:0048048; P:embryonic eye morphogenesis; IBA:RefGenome.::GO:0021797; P:forebrain anterior/posterior pattern specification; IBA:RefGenome.::GO:0071514; P:genetic imprinting; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0055001; P:muscle cell development; IBA:RefGenome.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:MGI.::GO:0045599; P:negative regulation of fat cell differentiation; IDA:MGI.::GO:0051248; P:negative regulation of protein metabolic process; IDA:MGI.::GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IDA:MGI.::GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0030910; P:olfactory placode formation; IBA:RefGenome.::GO:0001743; P:optic placode formation; IBA:RefGenome.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:MGI.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:MGI.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:MGI.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IMP:BHF-UCL.::GO:0030163; P:protein catabolic process; IDA:MGI.::GO:0051260; P:protein homooligomerization; IDA:MGI.::GO:0000209; P:protein polyubiquitination; IDA:MGI.::GO:0035412; P:regulation of catenin import into nucleus; IDA:MGI.::GO:0007605; P:sensory perception of sound; IMP:MGI.::GO:0035121; P:tail morphogenesis; IMP:MGI.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.::GO:0021881; P:Wnt receptor signaling pathway involved in forebrain neuron fate commitment; IBA:RefGenome.::GO:0090244; P:Wnt receptor signaling pathway involved in somitogenesis; IBA:RefGenome. | 2 | O70239 | 827 | AXIN1_RAT Axin-1 OS=Rattus norvegicus (Rat). ... | 40 | 0.56 | 31.2 | 38 | 60 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:BHF-UCL.::GO:0005938; C:cell cortex; IBA:RefGenome.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IBA:RefGenome.::GO:0005881; C:cytoplasmic microtubule; IBA:RefGenome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0070016; F:armadillo repeat domain binding; IDA:BHF-UCL.::GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0005096; F:GTPase activator activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IBA:RefGenome.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048320; P:axial mesoderm formation; IBA:RefGenome.::GO:0060823; P:canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation; IBA:RefGenome.::GO:0071407; P:cellular response to organic cyclic compound; IBA:RefGenome.::GO:0031122; P:cytoplasmic microtubule organization; IBA:RefGenome.::GO:0007368; P:determination of left/right symmetry; IBA:RefGenome.::GO:0009950; P:dorsal/ventral axis specification; IBA:RefGenome.::GO:0048048; P:embryonic eye morphogenesis; IBA:RefGenome.::GO:0060272; P:embryonic skeletal joint morphogenesis; IBA:RefGenome.::GO:0021797; P:forebrain anterior/posterior pattern specification; IBA:RefGenome.::GO:0055001; P:muscle cell development; IBA:RefGenome.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0045599; P:negative regulation of fat cell differentiation; IBA:RefGenome.::GO:0030910; P:olfactory placode formation; IBA:RefGenome.::GO:0001743; P:optic placode formation; IBA:RefGenome.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0051260; P:protein homooligomerization; IDA:RGD.::GO:0035412; P:regulation of catenin import into nucleus; IBA:RefGenome.::GO:0035121; P:tail morphogenesis; IBA:RefGenome.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0021881; P:Wnt receptor signaling pathway involved in forebrain neuron fate commitment; IBA:RefGenome.::GO:0090244; P:Wnt receptor signaling pathway involved in somitogenesis; IBA:RefGenome. | 3 | B7U540 | 433 | IRK18_HUMAN Inward rectifier potassium channe... | 29 | 1.3 | 30 | 45 | 66 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005242; F:inward rectifier potassium channel activity; IDA:UniProtKB. | | | | | | | | | | | 4 | P16793 | 668 | UL52_HCMVA Packaging protein UL52 OS=Human cy... | 27 | 1.8 | 29.6 | 48 | 56 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0019031; C:viral envelope; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | GO:0019069; P:viral capsid assembly; IEA:UniProtKB-KW. | 5 | O35732 | 484 | CFLAR_MOUSE CASP8 and FADD-like apoptosis reg... | 26 | 2 | 29.6 | 50 | 65 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:MGI.::GO:0006508; P:proteolysis; IEA:InterPro. | 6 | O42400 | 841 | AXIN1_CHICK Axin-1 OS=Gallus gallus (Chicken)... | 43 | 2.3 | 29.3 | 33 | 49 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IBA:RefGenome.::GO:0005938; C:cell cortex; IBA:RefGenome.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; ISS:AgBase.::GO:0005881; C:cytoplasmic microtubule; IBA:RefGenome.::GO:0005886; C:plasma membrane; IBA:RefGenome.::GO:0014069; C:postsynaptic density; IBA:RefGenome. | | | | | | | | | | GO:0070016; F:armadillo repeat domain binding; IBA:RefGenome.::GO:0008013; F:beta-catenin binding; ISS:AgBase.::GO:0005096; F:GTPase activator activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IBA:RefGenome.::GO:0048320; P:axial mesoderm formation; IBA:RefGenome.::GO:0060823; P:canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation; IBA:RefGenome.::GO:0008219; P:cell death; IBA:RefGenome.::GO:0071407; P:cellular response to organic cyclic compound; IBA:RefGenome.::GO:0031122; P:cytoplasmic microtubule organization; IBA:RefGenome.::GO:0007368; P:determination of left/right symmetry; IBA:RefGenome.::GO:0009950; P:dorsal/ventral axis specification; IBA:RefGenome.::GO:0048048; P:embryonic eye morphogenesis; IBA:RefGenome.::GO:0060272; P:embryonic skeletal joint morphogenesis; IBA:RefGenome.::GO:0021797; P:forebrain anterior/posterior pattern specification; IBA:RefGenome.::GO:0055001; P:muscle cell development; IBA:RefGenome.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0045599; P:negative regulation of fat cell differentiation; IBA:RefGenome.::GO:0030910; P:olfactory placode formation; IBA:RefGenome.::GO:0001743; P:optic placode formation; IBA:RefGenome.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0035412; P:regulation of catenin import into nucleus; IBA:RefGenome.::GO:0035121; P:tail morphogenesis; IBA:RefGenome.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0021881; P:Wnt receptor signaling pathway involved in forebrain neuron fate commitment; IBA:RefGenome.::GO:0090244; P:Wnt receptor signaling pathway involved in somitogenesis; IBA:RefGenome. | 7 | O15169 | 862 | AXIN1_HUMAN Axin-1 OS=Homo sapiens (Human). G... | 40 | 2.4 | 29.3 | 35 | 60 | GO:0034742; C:APC-Axin-1-beta-catenin complex; IDA:BHF-UCL.::GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:UniProtKB.::GO:0005938; C:cell cortex; IBA:RefGenome.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IBA:RefGenome.::GO:0005881; C:cytoplasmic microtubule; IBA:RefGenome.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016328; C:lateral plasma membrane; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0014069; C:postsynaptic density; IBA:RefGenome. | | | | | | | | | | GO:0070016; F:armadillo repeat domain binding; ISS:BHF-UCL.::GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0005096; F:GTPase activator activity; IBA:RefGenome.::GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0002039; F:p53 binding; IDA:MGI.::GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:BHF-UCL.::GO:0004871; F:signal transducer activity; IDA:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IBA:RefGenome.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048320; P:axial mesoderm formation; IBA:RefGenome.::GO:0060823; P:canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation; IBA:RefGenome.::GO:0043623; P:cellular protein complex assembly; IDA:BHF-UCL.::GO:0071407; P:cellular response to organic cyclic compound; IBA:RefGenome.::GO:0031122; P:cytoplasmic microtubule organization; IBA:RefGenome.::GO:0007368; P:determination of left/right symmetry; IBA:RefGenome.::GO:0009950; P:dorsal/ventral axis specification; IBA:RefGenome.::GO:0048048; P:embryonic eye morphogenesis; IBA:RefGenome.::GO:0060272; P:embryonic skeletal joint morphogenesis; IBA:RefGenome.::GO:0021797; P:forebrain anterior/posterior pattern specification; IBA:RefGenome.::GO:0055001; P:muscle cell development; IBA:RefGenome.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0045599; P:negative regulation of fat cell differentiation; IBA:RefGenome.::GO:0030910; P:olfactory placode formation; IBA:RefGenome.::GO:0001743; P:optic placode formation; IBA:RefGenome.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:BHF-UCL.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IMP:BHF-UCL.::GO:0035412; P:regulation of catenin import into nucleus; IBA:RefGenome.::GO:0035121; P:tail morphogenesis; IBA:RefGenome.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0021881; P:Wnt receptor signaling pathway involved in forebrain neuron fate commitment; IBA:RefGenome.::GO:0090244; P:Wnt receptor signaling pathway involved in somitogenesis; IBA:RefGenome. | 8 | Q14500 | 433 | IRK12_HUMAN ATP-sensitive inward rectifier po... | 19 | 2.7 | 29.3 | 58 | 79 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005242; F:inward rectifier potassium channel activity; TAS:ProtInc.::GO:0008200; F:ion channel inhibitor activity; TAS:ProtInc.::GO:0015459; F:potassium channel regulator activity; TAS:ProtInc. | | | | | | | | | | GO:0008015; P:blood circulation; NAS:ProtInc.::GO:0006936; P:muscle contraction; TAS:ProtInc.::GO:0008016; P:regulation of heart contraction; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 9 | P52188 | 427 | IRK12_RAT ATP-sensitive inward rectifier pota... | 19 | 2.8 | 28.9 | 58 | 79 | GO:0030425; C:dendrite; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0030315; C:T-tubule; IDA:RGD. | | | | | | | | | | GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:RGD. | | | | | | | | | | | 10 | P52187 | 427 | IRK12_MOUSE ATP-sensitive inward rectifier po... | 19 | 2.8 | 28.9 | 58 | 79 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro. | | | | | | | | | | | 11 | Q4TZY1 | 427 | IRK12_BOVIN ATP-sensitive inward rectifier po... | 19 | 2.9 | 28.9 | 58 | 79 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro. | | | | | | | | | | |
