| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
541 | P0A5S4 | 626 | PKNB_MYCTU Serine/threonine-protein kinase pk... | 189 | 0.000000000000009 | 79 | 31 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030145; F:manganese ion binding; IDA:MTBBASE.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE. | | | | | | | | | | GO:0040007; P:growth; IMP:MTBBASE.::GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0032091; P:negative regulation of protein binding; IDA:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0043388; P:positive regulation of DNA binding; IDA:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE.::GO:0008360; P:regulation of cell shape; IMP:MTBBASE.::GO:0051338; P:regulation of transferase activity; IDA:MTBBASE.::GO:0052572; P:response to host immune response; IDA:MTBBASE. | 542 | P0A5S5 | 626 | PKNB_MYCBO Serine/threonine-protein kinase pk... | 189 | 0.000000000000009 | 79 | 31 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 543 | Q91735 | 974 | EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenop... | 287 | 0.000000000000009 | 79.3 | 25 | 47 | GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB. | 544 | Q9SYM9 | 355 | Y1853_ARATH Receptor-like serine/threonine-pr... | 256 | 0.000000000000009 | 78.2 | 24 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 545 | Q5E9L6 | 487 | STK4_BOVIN Serine/threonine-protein kinase 4 ... | 268 | 0.000000000000009 | 78.6 | 26 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 546 | Q5CD18 | 503 | TGFR1_PIG TGF-beta receptor type-1 OS=Sus scr... | 276 | 0.000000000000009 | 78.6 | 28 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 547 | Q863I2 | 529 | OXSR1_PIG Serine/threonine-protein kinase OSR... | 290 | 0.000000000000009 | 79 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB. | 548 | A6ZU08 | 560 | TOS3_YEAS7 Serine/threonine-protein kinase TO... | 233 | 0.000000000000009 | 79 | 30 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 549 | P43637 | 560 | TOS3_YEAST Serine/threonine-protein kinase TO... | 233 | 0.000000000000009 | 79 | 30 | 43 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IMP:SGD.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 550 | Q8MYF1 | 456 | Y2070_DICDI Probable serine/threonine-protein... | 200 | 0.000000000000009 | 78.6 | 28 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 551 | Q9M3D7 | 667 | LRK14_ARATH Putative L-type lectin-domain con... | 279 | 0.00000000000001 | 79 | 25 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 552 | P36898 | 502 | BMR1B_MOUSE Bone morphogenetic protein recept... | 275 | 0.00000000000001 | 78.6 | 28 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005025; F:transforming growth factor beta receptor activity, type I; IMP:MGI. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; IMP:MGI.::GO:0001502; P:cartilage condensation; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IGI:MGI.::GO:0006703; P:estrogen biosynthetic process; NAS:UniProtKB.::GO:0006954; P:inflammatory response; IEP:UniProtKB.::GO:0001550; P:ovarian cumulus expansion; IMP:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IMP:MGI.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:MGI.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:MGI. | 553 | Q14289 | 1009 | FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=... | 285 | 0.00000000000001 | 79 | 26 | 44 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; NAS:ProtInc. | | | | | | | | | | GO:0042976; P:activation of Janus kinase activity; IMP:UniProtKB.::GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0070098; P:chemokine-mediated signaling pathway; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0002315; P:marginal zone B cell differentiation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; IMP:UniProtKB.::GO:0043267; P:negative regulation of potassium ion transport; IDA:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:2000538; P:positive regulation of B cell chemotaxis; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032960; P:regulation of inositol trisphosphate biosynthetic process; ISS:UniProtKB.::GO:0010758; P:regulation of macrophage chemotaxis; ISS:UniProtKB.::GO:2000058; P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0007172; P:signal complex assembly; TAS:ProtInc.::GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL. | 554 | Q96PN8 | 268 | TSSK3_HUMAN Testis-specific serine/threonine-... | 241 | 0.00000000000001 | 76.6 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 555 | Q54XL6 | 574 | FRAY1_DICDI Serine/threonine-protein kinase f... | 315 | 0.00000000000001 | 78.6 | 23 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 556 | Q9JM01 | 593 | CDKL3_RAT Cyclin-dependent kinase-like 3 OS=R... | 213 | 0.00000000000001 | 78.6 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 557 | P29323 | 1055 | EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo ... | 258 | 0.00000000000001 | 79 | 26 | 45 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0071679; P:commissural neuron axon guidance; ISS:UniProtKB.::GO:0022038; P:corpus callosum development; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.::GO:0060021; P:palate development; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0050878; P:regulation of body fluid levels; ISS:UniProtKB.::GO:0001655; P:urogenital system development; ISS:UniProtKB. | 558 | P54763 | 994 | EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus m... | 262 | 0.00000000000001 | 79 | 26 | 45 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0007413; P:axonal fasciculation; IMP:UniProtKB.::GO:0071679; P:commissural neuron axon guidance; IMP:UniProtKB.::GO:0022038; P:corpus callosum development; IMP:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; IMP:UniProtKB.::GO:0042472; P:inner ear morphogenesis; IMP:UniProtKB.::GO:0060021; P:palate development; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; IDA:UniProtKB.::GO:0050878; P:regulation of body fluid levels; IMP:UniProtKB.::GO:0001655; P:urogenital system development; IMP:UniProtKB. | 559 | P23572 | 297 | CDK1_DROME Cyclin-dependent kinase 1 OS=Droso... | 248 | 0.00000000000001 | 77 | 25 | 48 | GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0055059; P:asymmetric neuroblast division; IMP:FlyBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; IGI:FlyBase.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:FlyBase.::GO:0048142; P:germarium-derived cystoblast division; IMP:FlyBase.::GO:0007141; P:male meiosis I; TAS:FlyBase.::GO:0008315; P:meiotic G2/MI transition; TAS:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032880; P:regulation of protein localization; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0007284; P:spermatogonial cell division; IMP:FlyBase. | 560 | P30285 | 303 | CDK4_MOUSE Cyclin-dependent kinase 4 OS=Mus m... | 209 | 0.00000000000001 | 77 | 30 | 50 | GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0007165; P:signal transduction; IDA:MGI. | 561 | Q7ZUQ3 | 492 | STK3_DANRE Serine/threonine-protein kinase 3 ... | 262 | 0.00000000000001 | 78.6 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 562 | Q61288 | 502 | ACVL1_MOUSE Serine/threonine-protein kinase r... | 278 | 0.00000000000001 | 78.6 | 27 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0060840; P:artery development; IMP:BHF-UCL.::GO:0001974; P:blood vessel remodeling; IMP:BHF-UCL.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0042118; P:endothelial cell activation; TAS:DFLAT.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001946; P:lymphangiogenesis; IMP:BHF-UCL.::GO:0060836; P:lymphatic endothelial cell differentiation; IMP:BHF-UCL.::GO:0045602; P:negative regulation of endothelial cell differentiation; IDA:DFLAT.::GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:DFLAT.::GO:0030513; P:positive regulation of BMP signaling pathway; IDA:DFLAT.::GO:0045603; P:positive regulation of endothelial cell differentiation; IDA:DFLAT.::GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:DFLAT.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:DFLAT.::GO:0061298; P:retina vasculature development in camera-type eye; IMP:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:MGI.::GO:0060841; P:venous blood vessel development; IMP:BHF-UCL. | 563 | P35426 | 303 | CDK4_RAT Cyclin-dependent kinase 4 OS=Rattus ... | 209 | 0.00000000000001 | 77 | 30 | 50 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:RGD.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:RGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045787; P:positive regulation of cell cycle; TAS:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0045793; P:positive regulation of cell size; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0010288; P:response to lead ion; IMP:RGD.::GO:0033574; P:response to testosterone stimulus; IDA:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 564 | Q62862 | 448 | MP2K5_RAT Dual specificity mitogen-activated ... | 247 | 0.00000000000001 | 78.2 | 26 | 46 | GO:0005829; C:cytosol; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004708; F:MAP kinase kinase activity; IC:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0070375; P:ERK5 cascade; IMP:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.::GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; IMP:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IMP:BHF-UCL.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IMP:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; IMP:RGD.::GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:RGD.::GO:0051247; P:positive regulation of protein metabolic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL. | 565 | Q9WVS7 | 448 | MP2K5_MOUSE Dual specificity mitogen-activate... | 265 | 0.00000000000001 | 78.2 | 25 | 45 | GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007507; P:heart development; IMP:MGI. | 566 | O46680 | 499 | TGFR1_BOVIN TGF-beta receptor type-1 OS=Bos t... | 276 | 0.00000000000001 | 78.2 | 27 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005025; F:transforming growth factor beta receptor activity, type I; ISS:AgBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:AgBase. | 567 | Q6XUX3 | 929 | DUSTY_HUMAN Dual serine/threonine and tyrosin... | 185 | 0.00000000000001 | 78.6 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 568 | P16234 | 1089 | PGFRA_HUMAN Platelet-derived growth factor re... | 184 | 0.00000000000001 | 78.6 | 28 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005018; F:platelet-derived growth factor alpha-receptor activity; IDA:UniProtKB.::GO:0048407; F:platelet-derived growth factor binding; IDA:UniProtKB.::GO:0005161; F:platelet-derived growth factor receptor binding; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0038085; F:vascular endothelial growth factor binding; IPI:BHF-UCL.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IDA:BHF-UCL. | | | | | | | | | | GO:0055003; P:cardiac myofibril assembly; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IMP:UniProtKB.::GO:0048701; P:embryonic cranial skeleton morphogenesis; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0001553; P:luteinization; ISS:UniProtKB.::GO:0072277; P:metanephric glomerular capillary formation; ISS:UniProtKB.::GO:0010544; P:negative regulation of platelet activation; IDA:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IMP:UniProtKB.::GO:0070527; P:platelet aggregation; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0038091; P:positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway; IDA:BHF-UCL.::GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; IDA:BHF-UCL.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0010863; P:positive regulation of phospholipase C activity; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0050920; P:regulation of chemotaxis; IMP:UniProtKB.::GO:2000739; P:regulation of mesenchymal stem cell differentiation; IMP:UniProtKB.::GO:0061298; P:retina vasculature development in camera-type eye; ISS:UniProtKB.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 569 | Q9M342 | 639 | WAKLP_ARATH Wall-associated receptor kinase-l... | 218 | 0.00000000000001 | 78.6 | 28 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 570 | A4K2S1 | 487 | STK4_LEMCA Serine/threonine-protein kinase 4 ... | 268 | 0.00000000000001 | 78.2 | 25 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 571 | Q07497 | 1002 | EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallu... | 287 | 0.00000000000001 | 78.6 | 24 | 45 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IEA:InterPro. | | | | | | | | | | |
