| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
301 | O13147 | 500 | EPHB3_DANRE Ephrin type-B receptor 3 OS=Danio... | 290 | 4e-17 | 85.9 | 27 | 46 | GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB. | 302 | Q8QFP9 | 880 | TYRO3_XENLA Tyrosine-protein kinase receptor ... | 295 | 4e-17 | 86.3 | 23 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 303 | P31693 | 523 | SRC_RSVPA Tyrosine-protein kinase transformin... | 259 | 4e-17 | 85.9 | 25 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 304 | Q55BA0 | 765 | Y9866_DICDI Probable serine/threonine-protein... | 311 | 4e-17 | 86.3 | 23 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 305 | Q3UFB7 | 799 | NTRK1_MOUSE High affinity nerve growth factor... | 265 | 4e-17 | 86.3 | 29 | 47 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048406; F:nerve growth factor binding; ISS:UniProtKB.::GO:0010465; F:nerve growth factor receptor activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0060385; P:axonogenesis involved in innervation; IMP:UniProtKB.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0010623; P:developmental programmed cell death; ISS:UniProtKB.::GO:0042490; P:mechanoreceptor differentiation; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0043068; P:positive regulation of programmed cell death; ISS:UniProtKB.::GO:0032320; P:positive regulation of Ras GTPase activity; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; IMP:UniProtKB. | 306 | P54762 | 984 | EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo ... | 273 | 4e-17 | 86.3 | 27 | 48 | GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IDA:UniProtKB.::GO:0060326; P:cell chemotaxis; IDA:UniProtKB.::GO:0031589; P:cell-substrate adhesion; IDA:UniProtKB.::GO:0021952; P:central nervous system projection neuron axonogenesis; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; ISS:UniProtKB. | 307 | Q86AT8 | 638 | SPKA_DICDI Stress-activated protein kinase al... | 281 | 4e-17 | 85.9 | 23 | 46 | GO:0015629; C:actin cytoskeleton; IDA:dictyBase.::GO:0005737; C:cytoplasm; IDA:dictyBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0050793; P:regulation of developmental process; IMP:dictyBase.::GO:0006970; P:response to osmotic stress; IDA:dictyBase. | 308 | P35739 | 799 | NTRK1_RAT High affinity nerve growth factor r... | 265 | 4e-17 | 86.3 | 29 | 47 | GO:0030424; C:axon; IDA:RGD.::GO:0009986; C:cell surface; IDA:MGI.::GO:0031410; C:cytoplasmic vesicle; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048406; F:nerve growth factor binding; ISS:UniProtKB.::GO:0010465; F:nerve growth factor receptor activity; ISS:UniProtKB.::GO:0005166; F:neurotrophin p75 receptor binding; IPI:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0007411; P:axon guidance; IMP:RGD.::GO:0060385; P:axonogenesis involved in innervation; ISS:UniProtKB.::GO:0071363; P:cellular response to growth factor stimulus; IDA:MGI.::GO:0071316; P:cellular response to nicotine; IDA:RGD.::GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IMP:RGD.::GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IMP:RGD.::GO:0010623; P:developmental programmed cell death; IDA:UniProtKB.::GO:0007611; P:learning or memory; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0043526; P:neuroprotection; IDA:RGD.::GO:0021553; P:olfactory nerve development; IEP:RGD.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032320; P:positive regulation of Ras GTPase activity; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0014823; P:response to activity; IDA:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0051602; P:response to electrical stimulus; IDA:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0051599; P:response to hydrostatic pressure; IEP:RGD.::GO:0031667; P:response to nutrient levels; IDA:RGD.::GO:0009314; P:response to radiation; IEP:RGD.::GO:0060009; P:Sertoli cell development; IMP:RGD.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB. | 309 | Q8JH64 | 657 | BTK_CHICK Tyrosine-protein kinase BTK OS=Gall... | 267 | 5e-17 | 85.9 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 310 | Q13546 | 671 | RIPK1_HUMAN Receptor-interacting serine/threo... | 264 | 5e-17 | 85.9 | 25 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031264; C:death-inducing signaling complex; IDA:BHF-UCL.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:BHF-UCL.::GO:0043235; C:receptor complex; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070513; F:death domain binding; IPI:BHF-UCL.::GO:0005123; F:death receptor binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.::GO:0007257; P:activation of JUN kinase activity; TAS:BHF-UCL.::GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0060555; P:induction of necroptosis by extracellular signals; IMP:BHF-UCL.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; TAS:BHF-UCL.::GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; TAS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:BHF-UCL.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0070926; P:regulation of ATP:ADP antiporter activity; IMP:BHF-UCL.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IC:BHF-UCL. | 311 | P54756 | 1037 | EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo ... | 269 | 5e-17 | 85.9 | 26 | 48 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0009897; C:external side of plasma membrane; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0043025; C:neuronal cell body; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005791; C:rough endoplasmic reticulum; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0021766; P:hippocampus development; ISS:UniProtKB.::GO:0032793; P:positive regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB. | 312 | Q03137 | 986 | EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus m... | 268 | 5e-17 | 85.9 | 25 | 46 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0097161; F:DH domain binding; ISS:UniProtKB.::GO:0005004; F:GPI-linked ephrin receptor activity; IMP:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0007628; P:adult walking behavior; IMP:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021957; P:corticospinal tract morphogenesis; IMP:UniProtKB.::GO:0097156; P:fasciculation of motor neuron axon; IMP:UniProtKB.::GO:0097155; P:fasciculation of sensory neuron axon; IMP:UniProtKB.::GO:0008045; P:motor axon guidance; IMP:UniProtKB.::GO:0048681; P:negative regulation of axon regeneration; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:BHF-UCL.::GO:2001108; P:positive regulation of Rho guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0048710; P:regulation of astrocyte differentiation; IMP:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; IMP:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0032317; P:regulation of Rap GTPase activity; IMP:UniProtKB. | 313 | Q60805 | 994 | MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mu... | 267 | 5e-17 | 85.9 | 25 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0043277; P:apoptotic cell clearance; IMP:UniProtKB.::GO:0030168; P:platelet activation; IMP:MGI.::GO:0043491; P:protein kinase B signaling cascade; IGI:MGI.::GO:0060041; P:retina development in camera-type eye; IMP:MGI.::GO:0032940; P:secretion by cell; IMP:MGI.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:MGI. | 314 | P42682 | 527 | TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus ... | 264 | 5e-17 | 85.5 | 26 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; IMP:UniProtKB.::GO:0002250; P:adaptive immune response; IMP:UniProtKB.::GO:0032609; P:interferon-gamma production; IGI:MGI.::GO:0032633; P:interleukin-4 production; IGI:MGI.::GO:0001865; P:NK T cell differentiation; IGI:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 315 | Q54L00 | 650 | LIMKA_DICDI Probable LIM domain-containing se... | 279 | 6e-17 | 85.5 | 24 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 316 | A2QHV0 | 1336 | SEPH_ASPNC Cytokinesis protein sepH OS=Asperg... | 252 | 6e-17 | 85.9 | 27 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 317 | Q07496 | 986 | EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallu... | 268 | 6e-17 | 85.9 | 25 | 46 | GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0097161; F:DH domain binding; ISS:UniProtKB.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0097155; P:fasciculation of sensory neuron axon; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:2001108; P:positive regulation of Rho guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0032317; P:regulation of Rap GTPase activity; ISS:UniProtKB. | 318 | P54764 | 986 | EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo ... | 268 | 6e-17 | 85.9 | 25 | 46 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0097161; F:DH domain binding; IDA:UniProtKB.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB.::GO:0042731; F:PH domain binding; IPI:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021957; P:corticospinal tract morphogenesis; ISS:UniProtKB.::GO:0097156; P:fasciculation of motor neuron axon; ISS:UniProtKB.::GO:0097155; P:fasciculation of sensory neuron axon; ISS:UniProtKB.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0048681; P:negative regulation of axon regeneration; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:2001108; P:positive regulation of Rho guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0048710; P:regulation of astrocyte differentiation; ISS:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0032317; P:regulation of Rap GTPase activity; ISS:UniProtKB. | 319 | Q5B4Z3 | 1346 | SEPH_EMENI Cytokinesis protein sepH OS=194 / ... | 252 | 6e-17 | 85.9 | 27 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 320 | Q94CU5 | 943 | NEK5_ORYSJ Serine/threonine-protein kinase Ne... | 203 | 6e-17 | 85.5 | 29 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 321 | Q07494 | 984 | EPHB1_CHICK Ephrin type-B receptor 1 OS=Gallu... | 278 | 6e-17 | 85.5 | 26 | 47 | GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0031589; P:cell-substrate adhesion; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB. | 322 | Q8VCT9 | 570 | TESK2_MOUSE Dual specificity testis-specific ... | 205 | 7e-17 | 85.1 | 33 | 52 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 323 | P08922 | 2347 | ROS1_HUMAN Proto-oncogene tyrosine-protein ki... | 302 | 7e-17 | 85.9 | 27 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0002066; P:columnar/cuboidal epithelial cell development; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0032006; P:regulation of TOR signaling cascade; IDA:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 324 | Q9TTY2 | 823 | FER_CANFA Tyrosine-protein kinase Fer OS=Cani... | 260 | 7e-17 | 85.5 | 27 | 45 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 325 | P54744 | 622 | PKNB_MYCLE Serine/threonine-protein kinase pk... | 185 | 7e-17 | 85.1 | 32 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 326 | Q9V6K3 | 724 | ROR2_DROME Tyrosine-protein kinase transmembr... | 277 | 7e-17 | 85.5 | 24 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 327 | P10398 | 606 | ARAF_HUMAN Serine/threonine-protein kinase A-... | 202 | 7e-17 | 85.1 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB. | 328 | P53356 | 757 | HTK16_HYDVU Tyrosine-protein kinase HTK16 OS=... | 269 | 7e-17 | 85.5 | 27 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 329 | Q00993 | 888 | UFO_MOUSE Tyrosine-protein kinase receptor UF... | 296 | 7e-17 | 85.5 | 25 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0043277; P:apoptotic cell clearance; IGI:UniProtKB.::GO:0001974; P:blood vessel remodeling; IMP:MGI.::GO:0031668; P:cellular response to extracellular stimulus; IDA:MGI.::GO:0007167; P:enzyme linked receptor protein signaling pathway; IGI:MGI.::GO:0034101; P:erythrocyte homeostasis; IMP:MGI.::GO:0021885; P:forebrain cell migration; IGI:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IGI:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0042698; P:ovulation cycle; IGI:MGI.::GO:0030168; P:platelet activation; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:MGI.::GO:0032940; P:secretion by cell; IMP:MGI.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:MGI. | 330 | Q54WW7 | 695 | Y0010_DICDI Probable serine/threonine-protein... | 208 | 8e-17 | 85.1 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 331 | Q9SLI2 | 612 | NEK1_ARATH Serine/threonine-protein kinase Ne... | 267 | 8e-17 | 85.1 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | |
