| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | Q05555 | 494 | CP2AA_RABIT Cytochrome P450 2A10 OS=Oryctolag... | 207 | 2e-17 | 89 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 362 | P11509 | 494 | CP2A6_HUMAN Cytochrome P450 2A6 OS=Homo sapie... | 507 | 2e-17 | 88.6 | 22 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0008389; F:coumarin 7-hydroxylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IDA:UniProtKB. | | | | | | | | | | GO:0046226; P:coumarin catabolic process; IDA:BHF-UCL.::GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 363 | O70537 | 501 | CP3AV_MESAU Cytochrome P450 3A31 OS=Mesocrice... | 199 | 2e-17 | 88.6 | 30 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 364 | Q9DBX6 | 501 | CP2S1_MOUSE Cytochrome P450 2S1 OS=Mus muscul... | 145 | 2e-17 | 88.6 | 37 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 365 | P08684 | 503 | CP3A4_HUMAN Cytochrome P450 3A4 OS=Homo sapie... | 189 | 2e-17 | 88.6 | 32 | 54 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0047638; F:albendazole monooxygenase activity; IEA:EC.::GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc.::GO:0050591; F:quinine 3-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IDA:BHF-UCL.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:BHF-UCL.::GO:0070576; F:vitamin D 24-hydroxylase activity; IDA:BHF-UCL.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0008209; P:androgen metabolic process; TAS:BHF-UCL.::GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0006706; P:steroid catabolic process; IMP:BHF-UCL.::GO:0042359; P:vitamin D metabolic process; IC:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 366 | Q55AJ4 | 492 | C516B_DICDI Probable cytochrome P450 516B1 OS... | 489 | 2e-17 | 88.2 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 367 | Q02928 | 519 | CP4AB_HUMAN Cytochrome P450 4A11 OS=Homo sapi... | 166 | 2e-17 | 88.6 | 33 | 49 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 368 | P11707 | 501 | CP3A6_RABIT Cytochrome P450 3A6 OS=Oryctolagu... | 210 | 3e-17 | 88.2 | 31 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 369 | Q16696 | 494 | CP2AD_HUMAN Cytochrome P450 2A13 OS=Homo sapi... | 205 | 3e-17 | 88.2 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:UniProtKB. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 370 | P20815 | 502 | CP3A5_HUMAN Cytochrome P450 3A5 OS=Homo sapie... | 173 | 3e-17 | 88.2 | 33 | 51 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; TAS:ProtInc. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0042737; P:drug catabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; TAS:ProtInc.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 371 | Q54KV0 | 487 | C513B_DICDI Probable cytochrome P450 513B1 OS... | 185 | 3e-17 | 88.2 | 30 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 372 | Q8SPK0 | 504 | CP4AP_PIG Cytochrome P450 4A25 OS=Sus scrofa ... | 215 | 3e-17 | 87.8 | 32 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 373 | P14581 | 511 | CP4A7_RABIT Cytochrome P450 4A7 OS=Oryctolagu... | 200 | 4e-17 | 87.8 | 31 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 374 | Q6QNI4 | 494 | C71AJ_AMMMJ Psoralen synthase OS=Ammi majus (... | 463 | 4e-17 | 87.8 | 20 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IDA:UniProtKB. | | | | | | | | | | GO:0002238; P:response to molecule of fungal origin; IDA:UniProtKB. | 375 | P51538 | 503 | CP3A9_RAT Cytochrome P450 3A9 OS=Rattus norve... | 194 | 4e-17 | 87.8 | 32 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; TAS:RGD. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW. | 376 | P14579 | 511 | CP4A5_RABIT Cytochrome P450 4A5 OS=Oryctolagu... | 200 | 4e-17 | 87.8 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 377 | P56593 | 492 | CP2AC_MOUSE Cytochrome P450 2A12 OS=Mus muscu... | 444 | 4e-17 | 87.4 | 21 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 378 | O35084 | 507 | CP27B_MOUSE 25-hydroxyvitamin D-1 alpha hydro... | 167 | 5e-17 | 87.4 | 39 | 50 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004498; F:calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0033280; P:response to vitamin D; IDA:BHF-UCL.::GO:0042369; P:vitamin D catabolic process; IDA:BHF-UCL. | 379 | Q9VWR5 | 574 | CP306_DROME Cytochrome P450 306a1 OS=Drosophi... | 211 | 5e-17 | 87.4 | 27 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035302; F:ecdysteroid 25-hydroxylase activity; IDA:FlyBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0006697; P:ecdysone biosynthetic process; IDA:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase. | 380 | P17178 | 533 | CP27A_RAT Sterol 26-hydroxylase, mitochondria... | 163 | 6e-17 | 87.4 | 30 | 53 | | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0031073; F:cholesterol 26-hydroxylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IDA:RGD.::GO:0006706; P:steroid catabolic process; TAS:RGD. | 381 | Q64409 | 503 | CP3AH_CAVPO Cytochrome P450 3A17 OS=Cavia por... | 318 | 6e-17 | 87 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 382 | Q9VXY0 | 495 | CP4S3_DROME Probable cytochrome P450 4s3 OS=D... | 211 | 6e-17 | 87 | 33 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 383 | Q9DBG1 | 533 | CP27A_MOUSE Sterol 26-hydroxylase, mitochondr... | 162 | 7e-17 | 87 | 30 | 52 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 384 | O64899 | 487 | C80B1_ESCCA (S)-N-methylcoclaurine 3'-hydroxy... | 483 | 7e-17 | 86.7 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050593; F:N-methylcoclaurine 3'-monooxygenase activity; IEA:EC. | | | | | | | | | | | 385 | Q54WB9 | 519 | C513D_DICDI Probable cytochrome P450 513D1 OS... | 159 | 8e-17 | 87 | 33 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 386 | Q9HBI6 | 524 | CP4FB_HUMAN Cytochrome P450 4F11 OS=Homo sapi... | 183 | 8e-17 | 87 | 32 | 50 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; TAS:UniProtKB. | | | | | | | | | | GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 387 | C0SJS3 | 478 | ANGS_PASSA Angelicin synthase OS=Pastinaca sa... | 443 | 8e-17 | 86.7 | 23 | 42 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 388 | Q64464 | 503 | CP3AD_MOUSE Cytochrome P450 3A13 OS=Mus muscu... | 189 | 8e-17 | 86.7 | 33 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0010628; P:positive regulation of gene expression; IMP:MGI. | 389 | Q54Q53 | 509 | C519B_DICDI Probable cytochrome P450 519B1 OS... | 508 | 1e-16 | 86.7 | 24 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 390 | P79152 | 218 | CP3AJ_CAPAE Cytochrome P450 3A19 OS=Capra aeg... | 186 | 1e-16 | 83.2 | 32 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 391 | P93703 | 535 | C71C3_MAIZE Cytochrome P450 71C3 OS=Zea mays ... | 181 | 1e-16 | 86.3 | 36 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | |
