rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
991 | Q8C050 | 863 | KS6A5_MOUSE Ribosomal protein S6 kinase alpha... | 103 | 0.000001 | 53.9 | 29 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0043990; P:histone H2A-S1 phosphorylation; ISS:UniProtKB.::GO:0043987; P:histone H3-S10 phosphorylation; ISS:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB. | 992 | Q5R4K3 | 802 | KS6A5_PONAB Ribosomal protein S6 kinase alpha... | 183 | 0.000002 | 53.1 | 25 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0043990; P:histone H2A-S1 phosphorylation; ISS:UniProtKB.::GO:0043987; P:histone H3-S10 phosphorylation; ISS:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB. | 993 | Q54I36 | 1338 | PYK3_DICDI Dual specificity protein kinase py... | 182 | 0.000003 | 52.8 | 25 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0031156; P:regulation of sorocarp development; IMP:dictyBase. | 994 | Q15349 | 733 | KS6A2_HUMAN Ribosomal protein S6 kinase alpha... | 257 | 0.00001 | 50.8 | 25 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 995 | O12990 | 1153 | JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Da... | 246 | 0.00003 | 49.3 | 24 | 42 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 996 | Q09178 | 1156 | JAK1_CYPCA Tyrosine-protein kinase JAK1 OS=Cy... | 171 | 0.00006 | 48.5 | 25 | 46 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 997 | Q9R117 | 1180 | TYK2_MOUSE Non-receptor tyrosine-protein kina... | 229 | 0.0002 | 47 | 22 | 42 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 998 | P29597 | 1187 | TYK2_HUMAN Non-receptor tyrosine-protein kina... | 163 | 0.009 | 41.6 | 22 | 45 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome. | 999 | Q86HG9 | 1024 | Y9871_DICDI Probable serine/threonine-protein... | 129 | 0.036 | 39.7 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 1000 | Q75JK0 | 781 | ZAK1_DICDI Dual specificity protein kinase za... | 55 | 1.9 | 34.3 | 36 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IMP:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; IMP:UniProtKB.::GO:0001708; P:cell fate specification; IMP:UniProtKB.::GO:0033674; P:positive regulation of kinase activity; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0042659; P:regulation of cell fate specification; IMP:dictyBase.::GO:0061118; P:regulation of positive chemotaxis to cAMP; IMP:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. |