| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | Q9JI11 | 487 | STK4_MOUSE Serine/threonine-protein kinase 4 ... | 268 | 3e-16 | 82.8 | 27 | 46 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060706; P:cell differentiation involved in embryonic placenta development; IGI:MGI.::GO:0007417; P:central nervous system development; IGI:MGI.::GO:0003157; P:endocardium development; IGI:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0001841; P:neural tube formation; IGI:MGI.::GO:0001569; P:patterning of blood vessels; IGI:MGI.::GO:0060215; P:primitive hemopoiesis; IGI:MGI. | 422 | Q91694 | 985 | EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xen... | 272 | 3e-16 | 83.2 | 26 | 45 | GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0032317; P:regulation of Rap GTPase activity; ISS:UniProtKB. | 423 | Q55E58 | 3184 | PATS1_DICDI Probable serine/threonine-protein... | 283 | 3e-16 | 83.6 | 26 | 46 | GO:0042641; C:actomyosin; IPI:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:dictyBase. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 424 | Q9LZU4 | 676 | CRK4_ARATH Cysteine-rich receptor-like protei... | 209 | 3e-16 | 83.2 | 29 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042742; P:defense response to bacterium; IEP:TAIR.::GO:0012501; P:programmed cell death; IMP:TAIR.::GO:0009751; P:response to salicylic acid stimulus; IEP:TAIR. | 425 | P34152 | 1090 | FAK1_MOUSE Focal adhesion kinase 1 OS=Mus mus... | 281 | 3e-16 | 83.2 | 23 | 41 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:MGI.::GO:0043542; P:endothelial cell migration; IMP:MGI.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0040023; P:establishment of nucleus localization; IDA:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IDA:MGI.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050771; P:negative regulation of axonogenesis; IMP:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0051964; P:negative regulation of synapse assembly; IMP:MGI.::GO:0001764; P:neuron migration; IDA:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0007172; P:signal complex assembly; IEA:InterPro.::GO:0001570; P:vasculogenesis; IMP:MGI. | 426 | P53669 | 647 | LIMK1_RAT LIM domain kinase 1 OS=Rattus norve... | 206 | 3e-16 | 82.8 | 28 | 47 | GO:0044295; C:axonal growth cone; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB. | 427 | Q10GB1 | 599 | NEK1_ORYSJ Serine/threonine-protein kinase Ne... | 193 | 4e-16 | 82.8 | 31 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 428 | Q05397 | 1052 | FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sa... | 281 | 4e-16 | 83.2 | 23 | 41 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008432; F:JUN kinase binding; IDA:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; TAS:UniProtKB.::GO:0007411; P:axon guidance; TAS:UniProtKB.::GO:0048870; P:cell motility; TAS:UniProtKB.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0009790; P:embryo development; TAS:UniProtKB.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0030010; P:establishment of cell polarity; TAS:UniProtKB.::GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.::GO:0003007; P:heart morphogenesis; TAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0022408; P:negative regulation of cell-cell adhesion; IDA:BHF-UCL.::GO:0038007; P:netrin-activated signaling pathway; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0001890; P:placenta development; TAS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; TAS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:0010594; P:regulation of endothelial cell migration; TAS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; TAS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; IMP:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; TAS:UniProtKB.::GO:0007172; P:signal complex assembly; IEA:InterPro. | 429 | Q3UVC0 | 959 | KSR2_MOUSE Kinase suppressor of Ras 2 OS=Mus ... | 306 | 4e-16 | 82.8 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 430 | O13147 | 500 | EPHB3_DANRE Ephrin type-B receptor 3 OS=Danio... | 282 | 4e-16 | 82.4 | 27 | 44 | GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB. | 431 | P14616 | 1297 | INSRR_HUMAN Insulin receptor-related protein ... | 271 | 4e-16 | 83.2 | 28 | 44 | GO:0005887; C:integral to plasma membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; IEA:InterPro.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0071469; P:cellular response to alkalinity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB. | 432 | Q6FKD4 | 302 | PHO85_CANGA Negative regulator of the PHO sys... | 232 | 4e-16 | 80.9 | 27 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 433 | A4K2T0 | 487 | STK4_MACMU Serine/threonine-protein kinase 4 ... | 268 | 4e-16 | 82.4 | 27 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 434 | P0C5E2 | 654 | Y1839_ARATH Probable serine/threonine-protein... | 212 | 4e-16 | 82.4 | 25 | 48 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 435 | P53667 | 647 | LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapie... | 206 | 5e-16 | 82.4 | 28 | 46 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043005; C:neuron projection; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IDA:BHF-UCL.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 436 | A4K2Y1 | 487 | STK4_CHLAE Serine/threonine-protein kinase 4 ... | 268 | 5e-16 | 82 | 27 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 437 | Q91743 | 828 | FGFR4_XENLA Fibroblast growth factor receptor... | 294 | 5e-16 | 82.4 | 27 | 43 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 438 | P29323 | 1055 | EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo ... | 263 | 5e-16 | 82.8 | 27 | 44 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0071679; P:commissural neuron axon guidance; ISS:UniProtKB.::GO:0022038; P:corpus callosum development; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.::GO:0060021; P:palate development; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0050878; P:regulation of body fluid levels; ISS:UniProtKB.::GO:0001655; P:urogenital system development; ISS:UniProtKB. | 439 | Q9CAU7 | 606 | NEK2_ARATH Serine/threonine-protein kinase Ne... | 257 | 5e-16 | 82.4 | 27 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 440 | Q8RX66 | 568 | NEK3_ARATH Serine/threonine-protein kinase Ne... | 257 | 5e-16 | 82 | 26 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 441 | P21709 | 976 | EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo ... | 269 | 5e-16 | 82.4 | 26 | 45 | GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; IDA:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:UniProtKB. | 442 | P15208 | 1372 | INSR_MOUSE Insulin receptor OS=Mus musculus (... | 286 | 5e-16 | 82.8 | 28 | 44 | GO:0005901; C:caveola; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043559; F:insulin binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005009; F:insulin-activated receptor activity; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB.::GO:0051425; F:PTB domain binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0071363; P:cellular response to growth factor stimulus; IDA:MGI.::GO:0031017; P:exocrine pancreas development; IMP:MGI.::GO:0030238; P:male sex determination; IMP:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051290; P:protein heterotetramerization; ISS:UniProtKB. | 443 | Q86IX1 | 737 | DST1_DICDI Serine/threonine-protein kinase ds... | 261 | 5e-16 | 82.4 | 28 | 48 | GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase. | 444 | O14098 | 593 | CTK1_SCHPO CTD kinase subunit alpha OS=Schizo... | 214 | 5e-16 | 82 | 30 | 46 | GO:0005730; C:nucleolus; IDA:PomBase.::GO:0008024; C:positive transcription elongation factor complex b; NAS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0031566; P:contractile ring maintenance involved in cell cycle cytokinesis; IMP:PomBase.::GO:0031565; P:cytokinesis checkpoint; IMP:PomBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:PomBase.::GO:0031031; P:positive regulation of septation initiation signaling cascade; IGI:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 445 | P17157 | 305 | PHO85_YEAST Cyclin-dependent protein kinase P... | 232 | 5e-16 | 80.5 | 28 | 48 | GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0050849; P:negative regulation of calcium-mediated signaling; IGI:SGD.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0016242; P:negative regulation of macroautophagy; IMP:SGD.::GO:0045936; P:negative regulation of phosphate metabolic process; IGI:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.::GO:0016239; P:positive regulation of macroautophagy; IMP:SGD.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IGI:SGD.::GO:0032880; P:regulation of protein localization; IDA:SGD.::GO:0031647; P:regulation of protein stability; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD. | 446 | P54763 | 994 | EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus m... | 263 | 6e-16 | 82.4 | 27 | 44 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0007413; P:axonal fasciculation; IMP:UniProtKB.::GO:0071679; P:commissural neuron axon guidance; IMP:UniProtKB.::GO:0022038; P:corpus callosum development; IMP:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; IMP:UniProtKB.::GO:0042472; P:inner ear morphogenesis; IMP:UniProtKB.::GO:0060021; P:palate development; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; IDA:UniProtKB.::GO:0050878; P:regulation of body fluid levels; IMP:UniProtKB.::GO:0001655; P:urogenital system development; IMP:UniProtKB. | 447 | Q2QMH1 | 591 | NEK2_ORYSJ Serine/threonine-protein kinase Ne... | 193 | 6e-16 | 82 | 30 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 448 | A2ZMH2 | 591 | NEK2_ORYSI Serine/threonine-protein kinase Ne... | 193 | 6e-16 | 82 | 30 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 449 | Q13043 | 487 | STK4_HUMAN Serine/threonine-protein kinase 4 ... | 268 | 6e-16 | 82 | 27 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0043539; F:protein serine/threonine kinase activator activity; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0000902; P:cell morphogenesis; IDA:MGI.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI. | 450 | A1A5Q6 | 654 | SMK_RAT Sperm motility kinase OS=Rattus norve... | 259 | 6e-16 | 82 | 27 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 451 | P14617 | 1300 | INSRR_CAVPO Insulin receptor-related protein ... | 300 | 6e-16 | 82.4 | 27 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; IEA:InterPro.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0071469; P:cellular response to alkalinity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. |
