| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | P80192 | 1104 | M3K9_HUMAN Mitogen-activated protein kinase k... | 322 | 2e-17 | 86.7 | 27 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0004708; F:MAP kinase kinase activity; NAS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 332 | Q9NYL2 | 800 | MLTK_HUMAN Mitogen-activated protein kinase k... | 269 | 2e-17 | 86.7 | 26 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:UniProtKB.::GO:0007050; P:cell cycle arrest; IMP:UniProtKB.::GO:0008219; P:cell death; NAS:UniProtKB.::GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0009314; P:response to radiation; IDA:UniProtKB. | 333 | P55146 | 880 | TYRO3_RAT Tyrosine-protein kinase receptor TY... | 295 | 3e-17 | 86.3 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0043277; P:apoptotic cell clearance; ISS:UniProtKB.::GO:0021885; P:forebrain cell migration; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0045824; P:negative regulation of innate immune response; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; ISS:UniProtKB.::GO:0070050; P:neuron homeostasis; ISS:UniProtKB.::GO:0042698; P:ovulation cycle; ISS:UniProtKB.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032940; P:secretion by cell; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB. | 334 | Q96PY6 | 1258 | NEK1_HUMAN Serine/threonine-protein kinase Ne... | 259 | 3e-17 | 86.7 | 29 | 50 | GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0000242; C:pericentriolar material; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 335 | Q90ZK6 | 504 | ACVR1_CHICK Activin receptor type-1 OS=Gallus... | 292 | 3e-17 | 85.9 | 29 | 47 | | | | | | | | | | | GO:0048185; F:activin binding; TAS:AgBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:InterPro.::GO:0050431; F:transforming growth factor beta binding; IPI:AgBase.::GO:0005025; F:transforming growth factor beta receptor activity, type I; IDA:AgBase. | | | | | | | | | | GO:0060317; P:cardiac epithelial to mesenchymal transition; IMP:AgBase.::GO:0051216; P:cartilage development; IEP:AgBase.::GO:0042118; P:endothelial cell activation; IMP:AgBase.::GO:0035111; P:leg joint morphogenesis; IMP:AgBase.::GO:0035286; P:leg segmentation; IMP:AgBase.::GO:0001707; P:mesoderm formation; TAS:AgBase.::GO:0010694; P:positive regulation of alkaline phosphatase activity; IMP:AgBase.::GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:AgBase.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:AgBase.::GO:0030510; P:regulation of BMP signaling pathway; IDA:AgBase.::GO:0032330; P:regulation of chondrocyte differentiation; IGI:AgBase.::GO:0042325; P:regulation of phosphorylation; IPI:AgBase. | 336 | P54757 | 1005 | EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus ... | 269 | 3e-17 | 86.3 | 26 | 46 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0019933; P:cAMP-mediated signaling; IDA:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; IDA:UniProtKB.::GO:0021766; P:hippocampus development; ISS:UniProtKB.::GO:0032793; P:positive regulation of CREB transcription factor activity; IMP:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB. | 337 | Q93105 | 1393 | INSR_AEDAE Insulin-like receptor OS=Aedes aeg... | 273 | 3e-17 | 86.3 | 27 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043559; F:insulin binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005009; F:insulin-activated receptor activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB.::GO:0051425; F:PTB domain binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051290; P:protein heterotetramerization; ISS:UniProtKB. | 338 | Q64716 | 1300 | INSRR_RAT Insulin receptor-related protein OS... | 267 | 3e-17 | 86.3 | 28 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; IEA:InterPro.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 339 | P55144 | 880 | TYRO3_MOUSE Tyrosine-protein kinase receptor ... | 295 | 3e-17 | 86.3 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0043277; P:apoptotic cell clearance; IGI:UniProtKB.::GO:0021885; P:forebrain cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IGI:UniProtKB.::GO:0045824; P:negative regulation of innate immune response; IGI:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IGI:UniProtKB.::GO:0070050; P:neuron homeostasis; IMP:UniProtKB.::GO:0042698; P:ovulation cycle; IGI:MGI.::GO:0070527; P:platelet aggregation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0032940; P:secretion by cell; IMP:MGI.::GO:0007283; P:spermatogenesis; IGI:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:MGI. | 340 | Q12263 | 1142 | GIN4_YEAST Serine/threonine-protein kinase GI... | 232 | 3e-17 | 86.3 | 27 | 46 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007117; P:budding cell bud growth; IGI:SGD.::GO:0046777; P:protein autophosphorylation; IDA:SGD.::GO:0000135; P:septin checkpoint; IMP:SGD.::GO:0000921; P:septin ring assembly; IGI:SGD. | 341 | Q5IS82 | 825 | NTRK3_SAIBB NT-3 growth factor receptor OS=Sa... | 249 | 3e-17 | 85.9 | 29 | 46 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005030; F:neurotrophin receptor activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 342 | Q60629 | 876 | EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus m... | 268 | 4e-17 | 86.3 | 26 | 47 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0007411; P:axon guidance; IDA:UniProtKB.::GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0021766; P:hippocampus development; IDA:UniProtKB.::GO:0032793; P:positive regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.::GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB. | 343 | P80201 | 509 | ACVR1_RAT Activin receptor type-1 OS=Rattus n... | 290 | 4e-17 | 85.5 | 29 | 46 | GO:0048179; C:activin receptor complex; IDA:RGD. | | | | | | | | | | GO:0016361; F:activin receptor activity, type I; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IMP:RGD.::GO:0046332; F:SMAD binding; IMP:RGD. | | | | | | | | | | GO:0071385; P:cellular response to glucocorticoid stimulus; IEP:RGD.::GO:0048641; P:regulation of skeletal muscle tissue development; IEP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0001655; P:urogenital system development; IMP:MGI. | 344 | P37172 | 509 | ACVR1_MOUSE Activin receptor type-1 OS=Mus mu... | 290 | 4e-17 | 85.5 | 29 | 46 | GO:0045177; C:apical part of cell; IDA:MGI. | | | | | | | | | | GO:0048185; F:activin binding; IPI:MGI.::GO:0016361; F:activin receptor activity, type I; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050431; F:transforming growth factor beta binding; IDA:MGI.::GO:0005025; F:transforming growth factor beta receptor activity, type I; IDA:MGI. | | | | | | | | | | GO:0002526; P:acute inflammatory response; IEP:UniProtKB.::GO:0007368; P:determination of left/right symmetry; IMP:MGI.::GO:0001702; P:gastrulation with mouth forming second; IMP:MGI.::GO:0007281; P:germ cell development; IMP:MGI.::GO:0007507; P:heart development; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001707; P:mesoderm formation; IMP:MGI.::GO:0001755; P:neural crest cell migration; IMP:MGI.::GO:0001569; P:patterning of blood vessels; IMP:MGI.::GO:0060037; P:pharyngeal system development; IMP:MGI.::GO:0051145; P:smooth muscle cell differentiation; IMP:MGI.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:MGI. | 345 | Q9NWZ3 | 460 | IRAK4_HUMAN Interleukin-1 receptor-associated... | 222 | 4e-17 | 85.1 | 29 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; EXP:Reactome. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome. | 346 | P24062 | 1370 | IGF1R_RAT Insulin-like growth factor 1 recept... | 281 | 4e-17 | 86.3 | 27 | 44 | GO:0005901; C:caveola; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0001965; F:G-protein alpha-subunit binding; IPI:RGD.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005010; F:insulin-like growth factor-activated receptor activity; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:RGD.::GO:0030010; P:establishment of cell polarity; IMP:RGD.::GO:0051389; P:inactivation of MAPKK activity; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0032467; P:positive regulation of cytokinesis; IMP:RGD.::GO:0090031; P:positive regulation of steroid hormone biosynthetic process; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0051262; P:protein tetramerization; ISS:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.::GO:0033197; P:response to vitamin E; IEP:RGD. | 347 | Q86CS2 | 668 | ATG1_DICDI Serine/threonine-protein kinase at... | 198 | 4e-17 | 85.5 | 31 | 51 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0048102; P:autophagic cell death; IMP:dictyBase.::GO:0006995; P:cellular response to nitrogen starvation; IMP:dictyBase.::GO:0016236; P:macroautophagy; IMP:dictyBase.::GO:0070265; P:necrotic cell death; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 348 | P16277 | 499 | BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus ... | 272 | 5e-17 | 85.1 | 26 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 349 | Q8QFP9 | 880 | TYRO3_XENLA Tyrosine-protein kinase receptor ... | 295 | 5e-17 | 85.5 | 24 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 350 | O59790 | 355 | ARK1_SCHPO Serine/threonine-protein kinase ar... | 223 | 5e-17 | 84 | 28 | 48 | GO:0032133; C:chromosome passenger complex; NAS:PomBase.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0051233; C:spindle midzone; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0051315; P:attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; TAS:PomBase.::GO:0033205; P:cell cycle cytokinesis; IMP:PomBase.::GO:2000775; P:histone H3-S10 phosphorylation involved in chromosome condensation; IDA:PomBase.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0034501; P:protein localization to kinetochore; IGI:PomBase.::GO:0034503; P:protein localization to nucleolar rDNA repeats; IGI:PomBase.::GO:0031134; P:sister chromatid biorientation; TAS:PomBase. | 351 | Q69ZM6 | 1316 | STK36_MOUSE Serine/threonine-protein kinase 3... | 219 | 5e-17 | 85.9 | 28 | 51 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; IDA:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:UniProtKB. | 352 | Q7SY52 | 974 | STK10_DANRE Serine/threonine-protein kinase 1... | 313 | 5e-17 | 85.5 | 27 | 45 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB. | 353 | P53668 | 647 | LIMK1_MOUSE LIM domain kinase 1 OS=Mus muscul... | 206 | 5e-17 | 85.5 | 29 | 47 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045773; P:positive regulation of axon extension; IGI:MGI. | 354 | Q09170 | 460 | CDS1_SCHPO Serine/threonine-protein kinase cd... | 228 | 5e-17 | 84.7 | 29 | 49 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031573; P:intra-S DNA damage checkpoint; IDA:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; TAS:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase. | 355 | Q60751 | 1373 | IGF1R_MOUSE Insulin-like growth factor 1 rece... | 282 | 6e-17 | 85.5 | 27 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005010; F:insulin-like growth factor-activated receptor activity; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IMP:MGI.::GO:0031017; P:exocrine pancreas development; IMP:MGI.::GO:0030238; P:male sex determination; IMP:MGI.::GO:0030879; P:mammary gland development; IMP:MGI.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:MGI.::GO:0060740; P:prostate gland epithelium morphogenesis; IMP:MGI.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051262; P:protein tetramerization; ISS:UniProtKB. | 356 | P38692 | 1080 | KIC1_YEAST Serine/threonine-protein kinase KI... | 258 | 6e-17 | 85.5 | 28 | 48 | GO:0005933; C:cellular bud; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007118; P:budding cell apical bud growth; IMP:SGD.::GO:0000902; P:cell morphogenesis; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD. | 357 | Q61UC4 | 811 | KRAF1_CAEBR Raf homolog serine/threonine-prot... | 227 | 6e-17 | 85.1 | 26 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 358 | P08069 | 1367 | IGF1R_HUMAN Insulin-like growth factor 1 rece... | 309 | 6e-17 | 85.5 | 26 | 44 | GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0043559; F:insulin binding; IPI:BHF-UCL.::GO:0005158; F:insulin receptor binding; IDA:BHF-UCL.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0031994; F:insulin-like growth factor I binding; IPI:BHF-UCL.::GO:0005010; F:insulin-like growth factor-activated receptor activity; IDA:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0006955; P:immune response; IMP:BHF-UCL.::GO:0051389; P:inactivation of MAPKK activity; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IC:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0045740; P:positive regulation of DNA replication; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB. | 359 | P14234 | 517 | FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus ... | 274 | 7e-17 | 84.7 | 24 | 45 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IDA:UniProtKB. | | | | | | | | | | GO:0050830; P:defense response to Gram-positive bacterium; IMP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; IDA:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; IDA:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; TAS:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0045088; P:regulation of innate immune response; IMP:UniProtKB.::GO:0050764; P:regulation of phagocytosis; IMP:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; IDA:UniProtKB. | 360 | P54755 | 1013 | EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallu... | 269 | 7e-17 | 85.1 | 26 | 47 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0021766; P:hippocampus development; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB. | 361 | Q6XHB2 | 1726 | ROCO4_DICDI Probable serine/threonine-protein... | 295 | 7e-17 | 85.5 | 27 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
