| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | P00542 | 609 | FES_FSVGA Tyrosine-protein kinase transformin... | 257 | 4e-19 | 91.7 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 212 | P51451 | 505 | BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo... | 274 | 4e-19 | 91.7 | 25 | 49 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB. | 213 | Q54MV2 | 715 | MRKB_DICDI Probable serine/threonine-protein ... | 239 | 4e-19 | 92 | 30 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | | 214 | P07332 | 822 | FES_HUMAN Tyrosine-protein kinase Fes/Fps OS=... | 260 | 4e-19 | 92 | 29 | 46 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0015630; C:microtubule cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034987; F:immunoglobulin receptor binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0031116; P:positive regulation of microtubule polymerization; IMP:UniProtKB.::GO:0045639; P:positive regulation of myeloid cell differentiation; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IMP:UniProtKB.::GO:2000145; P:regulation of cell motility; IMP:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB. | 215 | Q9R0A5 | 511 | NEK3_MOUSE Serine/threonine-protein kinase Ne... | 261 | 4e-19 | 91.3 | 28 | 49 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 216 | Q91009 | 778 | NTRK1_CHICK High affinity nerve growth factor... | 287 | 4e-19 | 91.7 | 30 | 46 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048406; F:nerve growth factor binding; ISS:UniProtKB.::GO:0010465; F:nerve growth factor receptor activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0060385; P:axonogenesis involved in innervation; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0032320; P:positive regulation of Ras GTPase activity; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB. | 217 | P00522 | 1620 | ABL_DROME Tyrosine-protein kinase Abl OS=Dros... | 267 | 5e-19 | 92 | 27 | 47 | GO:0045179; C:apical cortex; IDA:FlyBase.::GO:0030424; C:axon; IDA:FlyBase.::GO:0005911; C:cell-cell junction; IDA:FlyBase.::GO:0005829; C:cytosol; IDA:FlyBase.::GO:0019897; C:extrinsic to plasma membrane; IDA:FlyBase.::GO:0005927; C:muscle tendon junction; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007417; P:central nervous system development; IGI:FlyBase.::GO:0007303; P:cytoplasmic transport, nurse cell to oocyte; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0003382; P:epithelial cell morphogenesis; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0045886; P:negative regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0008064; P:regulation of actin polymerization or depolymerization; TAS:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0032880; P:regulation of protein localization; IDA:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase.::GO:0007370; P:ventral furrow formation; IMP:FlyBase. | 218 | Q99N57 | 648 | RAF1_MOUSE RAF proto-oncogene serine/threonin... | 223 | 5e-19 | 91.7 | 29 | 49 | GO:0005829; C:cytosol; TAS:MGI.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0031143; C:pseudopodium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017016; F:Ras GTPase binding; IPI:MGI. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; IMP:MGI. | 219 | P05625 | 647 | RAF1_CHICK RAF proto-oncogene serine/threonin... | 223 | 5e-19 | 91.7 | 29 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 220 | C0LGS2 | 1136 | Y4361_ARATH Probable LRR receptor-like serine... | 167 | 5e-19 | 92 | 34 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 221 | P27966 | 450 | RMIL_AVEVR Serine/threonine-protein kinase-tr... | 214 | 5e-19 | 90.9 | 29 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 222 | P30530 | 894 | UFO_HUMAN Tyrosine-protein kinase receptor UF... | 288 | 5e-19 | 91.7 | 27 | 45 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0048469; P:cell maturation; IEP:UniProtKB.::GO:0035457; P:cellular response to interferon-alpha; IDA:UniProtKB.::GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.::GO:0097028; P:dendritic cell differentiation; IEP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:2000669; P:negative regulation of dendritic cell apoptotic process; IDA:UniProtKB.::GO:0032689; P:negative regulation of interferon-gamma production; IDA:UniProtKB.::GO:0001961; P:positive regulation of cytokine-mediated signaling pathway; IDA:UniProtKB.::GO:0032825; P:positive regulation of natural killer cell differentiation; IDA:UniProtKB. | 223 | Q9HC98 | 313 | NEK6_HUMAN Serine/threonine-protein kinase Ne... | 266 | 6e-19 | 89 | 24 | 46 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IDA:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000772; P:regulation of cellular senescence; TAS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IDA:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB. | 224 | P25020 | 526 | SRC_RSVH1 Tyrosine-protein kinase transformin... | 259 | 6e-19 | 90.9 | 25 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 225 | Q54L00 | 650 | LIMKA_DICDI Probable LIM domain-containing se... | 273 | 6e-19 | 91.3 | 26 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 226 | Q8SRU0 | 319 | CSK2A_ENCCU Probable casein kinase II subunit... | 202 | 6e-19 | 89 | 27 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 227 | P59895 | 313 | NEK6_RAT Serine/threonine-protein kinase Nek6... | 266 | 6e-19 | 88.6 | 24 | 46 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB. | 228 | A2BD05 | 313 | NEK6_PIG Serine/threonine-protein kinase Nek6... | 266 | 6e-19 | 88.6 | 24 | 46 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 229 | P14238 | 820 | FES_FELCA Tyrosine-protein kinase Fes/Fps OS=... | 257 | 7e-19 | 91.3 | 28 | 46 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0015630; C:microtubule cytoskeleton; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034987; F:immunoglobulin receptor binding; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0031116; P:positive regulation of microtubule polymerization; ISS:UniProtKB.::GO:0045639; P:positive regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB. | 230 | Q95UN8 | 1161 | M3KSL_DROME Mitogen-activated protein kinase ... | 298 | 7e-19 | 91.7 | 27 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.::GO:0071361; P:cellular response to ethanol; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0048804; P:imaginal disc-derived female genitalia morphogenesis; IMP:FlyBase.::GO:0048803; P:imaginal disc-derived male genitalia morphogenesis; IMP:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IMP:FlyBase.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 231 | Q8JH64 | 657 | BTK_CHICK Tyrosine-protein kinase BTK OS=Gall... | 263 | 7e-19 | 90.9 | 26 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 232 | P18161 | 1155 | SPLB_DICDI Dual specificity protein kinase sp... | 265 | 7e-19 | 91.7 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 233 | Q54TA1 | 749 | DRKC_DICDI Probable serine/threonine-protein ... | 272 | 7e-19 | 91.3 | 30 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030670; C:phagocytic vesicle membrane; IDA:dictyBase.::GO:0032010; C:phagolysosome; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0001845; P:phagolysosome assembly; IMP:dictyBase. | 234 | Q62662 | 506 | FRK_RAT Tyrosine-protein kinase FRK OS=Rattus... | 267 | 8e-19 | 90.5 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEP:RGD. | 235 | Q54H45 | 690 | DRKB_DICDI Probable serine/threonine-protein ... | 251 | 8e-19 | 90.9 | 29 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 236 | O76997 | 794 | TRK1_LYMST Putative neurotrophin receptor LTR... | 311 | 8e-19 | 90.9 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 237 | Q6ZN16 | 1313 | M3K15_HUMAN Mitogen-activated protein kinase ... | 256 | 8e-19 | 91.3 | 27 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 238 | P00543 | 477 | FES_FSVST Tyrosine-protein kinase transformin... | 273 | 9e-19 | 90.1 | 27 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 239 | Q9QVP9 | 1009 | FAK2_MOUSE Protein-tyrosine kinase 2-beta OS=... | 273 | 9e-19 | 91.3 | 26 | 45 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0045453; P:bone resorption; IMP:UniProtKB.::GO:0070098; P:chemokine-mediated signaling pathway; IMP:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0002315; P:marginal zone B cell differentiation; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:2000538; P:positive regulation of B cell chemotaxis; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0001954; P:positive regulation of cell-matrix adhesion; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051000; P:positive regulation of nitric-oxide synthase activity; IMP:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0050848; P:regulation of calcium-mediated signaling; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0030826; P:regulation of cGMP biosynthetic process; IMP:UniProtKB.::GO:0010752; P:regulation of cGMP-mediated signaling; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0032960; P:regulation of inositol trisphosphate biosynthetic process; IMP:UniProtKB.::GO:0010758; P:regulation of macrophage chemotaxis; IMP:UniProtKB.::GO:0045428; P:regulation of nitric oxide biosynthetic process; IMP:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IMP:UniProtKB.::GO:0007172; P:signal complex assembly; IEA:InterPro.::GO:0002040; P:sprouting angiogenesis; IMP:UniProtKB.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB. | 240 | P09769 | 529 | FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo... | 272 | 9e-19 | 90.5 | 26 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034988; F:Fc-gamma receptor I complex binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.::GO:0009615; P:response to virus; TAS:ProtInc. | 241 | P70600 | 1009 | FAK2_RAT Protein-tyrosine kinase 2-beta OS=Ra... | 269 | 9e-19 | 91.3 | 26 | 45 | GO:0030424; C:axon; IDA:RGD.::GO:0005938; C:cell cortex; IDA:RGD.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0043423; F:3-phosphoinositide-dependent protein kinase binding; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0042976; P:activation of Janus kinase activity; IMP:RGD.::GO:0032863; P:activation of Rac GTPase activity; IMP:RGD.::GO:0043534; P:blood vessel endothelial cell migration; IMP:RGD.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0070098; P:chemokine-mediated signaling pathway; ISS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IMP:RGD.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IMP:RGD.::GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0014009; P:glial cell proliferation; IEP:RGD.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; IMP:RGD.::GO:0002315; P:marginal zone B cell differentiation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0031175; P:neuron projection development; IMP:RGD.::GO:0001556; P:oocyte maturation; IMP:RGD.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:2000538; P:positive regulation of B cell chemotaxis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IEP:RGD.::GO:0001954; P:positive regulation of cell-matrix adhesion; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IMP:RGD.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032960; P:regulation of inositol trisphosphate biosynthetic process; ISS:UniProtKB.::GO:0010758; P:regulation of macrophage chemotaxis; ISS:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0042220; P:response to cocaine; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IPI:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0006970; P:response to osmotic stress; IEP:RGD.::GO:0007172; P:signal complex assembly; IEA:InterPro.::GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.::GO:0043149; P:stress fiber assembly; IMP:RGD. |
