| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | P00528 | 552 | SRC64_DROME Tyrosine-protein kinase Src64B OS... | 252 | 3e-20 | 95.1 | 26 | 48 | GO:0045172; C:germline ring canal; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007349; P:cellularization; IMP:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0008302; P:female germline ring canal formation, actin assembly; IMP:FlyBase.::GO:0008335; P:female germline ring canal stabilization; IMP:FlyBase.::GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030717; P:karyosome formation; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:FlyBase.::GO:0030046; P:parallel actin filament bundle assembly; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IGI:FlyBase.::GO:0008064; P:regulation of actin polymerization or depolymerization; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase. | 152 | P00519 | 1130 | ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Ho... | 264 | 3e-20 | 95.9 | 25 | 50 | GO:0015629; C:actin cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0003785; F:actin monomer binding; TAS:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:BHF-UCL.::GO:0004515; F:nicotinate-nucleotide adenylyltransferase activity; TAS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006975; P:DNA damage induced protein phosphorylation; IDA:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; TAS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006298; P:mismatch repair; TAS:ProtInc.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0051353; P:positive regulation of oxidoreductase activity; IDA:BHF-UCL.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.::GO:2001020; P:regulation of response to DNA damage stimulus; IDA:UniProtKB.::GO:0000115; P:regulation of transcription involved in S phase of mitotic cell cycle; TAS:ProtInc. | 153 | P00530 | 873 | FPS_FUJSV Tyrosine-protein kinase transformin... | 273 | 3e-20 | 95.9 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0018108; P:peptidyl-tyrosine phosphorylation; IEA:InterPro.::GO:0016032; P:viral reproduction; IEA:InterPro. | 154 | A1X150 | 1380 | MET_ECHTE Hepatocyte growth factor receptor O... | 276 | 3e-20 | 95.9 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 155 | P18160 | 2410 | SPLA_DICDI Dual specificity protein kinase sp... | 291 | 3e-20 | 96.3 | 28 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 156 | Q8BKG3 | 1062 | PTK7_MOUSE Inactive tyrosine-protein kinase 7... | 249 | 3e-20 | 95.5 | 24 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro. | | | | | | | | | | GO:0003401; P:axis elongation; IMP:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0060026; P:convergent extension; IMP:MGI.::GO:0045198; P:establishment of epithelial cell apical/basal polarity; IMP:MGI.::GO:0001736; P:establishment of planar polarity; IMP:MGI.::GO:0060484; P:lung-associated mesenchyme development; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 157 | Q54VC0 | 418 | Y9865_DICDI Probable serine/threonine-protein... | 276 | 4e-20 | 93.6 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 158 | Q3UFB7 | 799 | NTRK1_MOUSE High affinity nerve growth factor... | 287 | 4e-20 | 95.1 | 29 | 46 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048406; F:nerve growth factor binding; ISS:UniProtKB.::GO:0010465; F:nerve growth factor receptor activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0060385; P:axonogenesis involved in innervation; IMP:UniProtKB.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0010623; P:developmental programmed cell death; ISS:UniProtKB.::GO:0042490; P:mechanoreceptor differentiation; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0043068; P:positive regulation of programmed cell death; ISS:UniProtKB.::GO:0032320; P:positive regulation of Ras GTPase activity; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; IMP:UniProtKB. | 159 | A7J1T0 | 961 | M313B_XENLA Mitogen-activated protein kinase ... | 305 | 4e-20 | 95.1 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; IEA:InterPro. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IEA:InterPro. | 160 | Q13308 | 1070 | PTK7_HUMAN Inactive tyrosine-protein kinase 7... | 249 | 5e-20 | 95.1 | 24 | 49 | GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL. | 161 | Q54QQ1 | 1387 | PHG2_DICDI Serine/threonine-protein kinase ph... | 271 | 5e-20 | 95.5 | 27 | 48 | GO:0030666; C:endocytic vesicle membrane; IDA:dictyBase.::GO:0005886; C:plasma membrane; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.::GO:0017016; F:Ras GTPase binding; IPI:dictyBase. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:dictyBase.::GO:0000902; P:cell morphogenesis; IMP:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0031670; P:cellular response to nutrient; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0051489; P:regulation of filopodium assembly; IMP:dictyBase.::GO:0031156; P:regulation of sorocarp development; IMP:dictyBase. | 162 | Q9V9J3 | 517 | SRC42_DROME Tyrosine-protein kinase Src42A OS... | 283 | 5e-20 | 94.4 | 24 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0043277; P:apoptotic cell clearance; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0007395; P:dorsal closure, spreading of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IGI:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IGI:FlyBase.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase. | 163 | P00532 | 323 | RAF_MSV36 Serine/threonine-protein kinase-tra... | 238 | 5e-20 | 92 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 164 | Q62838 | 868 | MUSK_RAT Muscle, skeletal receptor tyrosine p... | 288 | 5e-20 | 94.7 | 26 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IDA:RGD.::GO:0009897; C:external side of plasma membrane; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031594; C:neuromuscular junction; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0090102; P:cochlea development; IEP:RGD.::GO:0060291; P:long-term synaptic potentiation; IMP:RGD.::GO:0007613; P:memory; IMP:RGD.::GO:0010629; P:negative regulation of gene expression; IDA:RGD.::GO:0007528; P:neuromuscular junction development; IEP:RGD.::GO:0010628; P:positive regulation of gene expression; IMP:RGD.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:RGD.::GO:0045887; P:positive regulation of synaptic growth at neuromuscular junction; IMP:RGD.::GO:0032224; P:positive regulation of synaptic transmission, cholinergic; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0043113; P:receptor clustering; IMP:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0051602; P:response to electrical stimulus; IMP:RGD.::GO:0014850; P:response to muscle activity; IEP:RGD.::GO:0060041; P:retina development in camera-type eye; IEP:RGD. | 165 | P25848 | 1307 | PHY1_CERPU Light-sensor Protein kinase OS=Cer... | 243 | 5e-20 | 95.1 | 31 | 46 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008020; F:G-protein coupled photoreceptor activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 166 | Q7T6Y2 | 1624 | YR831_MIMIV Putative serine/threonine-protein... | 283 | 6e-20 | 95.1 | 26 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016849; F:phosphorus-oxygen lyase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 167 | Q08881 | 620 | ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=... | 258 | 6e-20 | 94.4 | 26 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; ISS:UniProtKB.::GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 168 | Q5R8X7 | 966 | M3K13_PONAB Mitogen-activated protein kinase ... | 274 | 6e-20 | 94.7 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0007254; P:JNK cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 169 | P35991 | 659 | BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus ... | 264 | 6e-20 | 94.4 | 27 | 48 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 170 | Q12866 | 999 | MERTK_HUMAN Tyrosine-protein kinase Mer OS=Ho... | 293 | 6e-20 | 94.7 | 27 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0016028; C:rhabdomere; IDA:BHF-UCL.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0050766; P:positive regulation of phagocytosis; IDA:UniProtKB. | 171 | Q7TSC3 | 627 | NEK5_MOUSE Serine/threonine-protein kinase Ne... | 200 | 8e-20 | 94 | 31 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 172 | Q9ES74 | 302 | NEK7_MOUSE Serine/threonine-protein kinase Ne... | 255 | 8e-20 | 91.3 | 25 | 47 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | | 173 | P51957 | 841 | NEK4_HUMAN Serine/threonine-protein kinase Ne... | 261 | 8e-20 | 94.4 | 28 | 47 | GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 174 | P42679 | 507 | MATK_HUMAN Megakaryocyte-associated tyrosine-... | 255 | 8e-20 | 93.6 | 29 | 47 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc. | 175 | D3ZBE5 | 302 | NEK7_RAT Serine/threonine-protein kinase Nek7... | 255 | 9e-20 | 91.3 | 25 | 47 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | | 176 | P35739 | 799 | NTRK1_RAT High affinity nerve growth factor r... | 287 | 9e-20 | 94 | 28 | 46 | GO:0030424; C:axon; IDA:RGD.::GO:0009986; C:cell surface; IDA:MGI.::GO:0031410; C:cytoplasmic vesicle; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048406; F:nerve growth factor binding; ISS:UniProtKB.::GO:0010465; F:nerve growth factor receptor activity; ISS:UniProtKB.::GO:0005166; F:neurotrophin p75 receptor binding; IPI:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0007411; P:axon guidance; IMP:RGD.::GO:0060385; P:axonogenesis involved in innervation; ISS:UniProtKB.::GO:0071363; P:cellular response to growth factor stimulus; IDA:MGI.::GO:0071316; P:cellular response to nicotine; IDA:RGD.::GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IMP:RGD.::GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IMP:RGD.::GO:0010623; P:developmental programmed cell death; IDA:UniProtKB.::GO:0007611; P:learning or memory; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0043526; P:neuroprotection; IDA:RGD.::GO:0021553; P:olfactory nerve development; IEP:RGD.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032320; P:positive regulation of Ras GTPase activity; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0014823; P:response to activity; IDA:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0051602; P:response to electrical stimulus; IDA:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0051599; P:response to hydrostatic pressure; IEP:RGD.::GO:0031667; P:response to nutrient levels; IDA:RGD.::GO:0009314; P:response to radiation; IEP:RGD.::GO:0060009; P:Sertoli cell development; IMP:RGD.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB. | 177 | P11345 | 648 | RAF1_RAT RAF proto-oncogene serine/threonine-... | 223 | 9e-20 | 94 | 30 | 50 | GO:0005829; C:cytosol; TAS:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IMP:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD. | | | | | | | | | | GO:0007507; P:heart development; IEP:RGD.::GO:0001666; P:response to hypoxia; IDA:RGD. | 178 | Q6P3R8 | 708 | NEK5_HUMAN Serine/threonine-protein kinase Ne... | 224 | 9e-20 | 94 | 31 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 179 | C0LGP9 | 784 | IMK3_ARATH Probable leucine-rich repeat recep... | 308 | 9e-20 | 94 | 23 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 180 | Q7T6X2 | 1657 | YR826_MIMIV Putative serine/threonine-protein... | 280 | 1e-19 | 94.4 | 24 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016849; F:phosphorus-oxygen lyase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 181 | P57097 | 994 | MERTK_RAT Tyrosine-protein kinase Mer OS=Ratt... | 271 | 1e-19 | 94 | 27 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0001750; C:photoreceptor outer segment; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; NAS:RGD. | | | | | | | | | | |
