| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | A4RKC3 | 1591 | DCL1_MAGO7 Dicer-like protein 1 OS=blast fung... | 1442 | 1e-85 | 315 | 26 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 2 | Q2H0G2 | 1607 | DCL1_CHAGB Dicer-like protein 1 OS=6347 / NRR... | 1538 | 1e-83 | 308 | 27 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 3 | Q7XD96 | 1637 | DCL3B_ORYSJ Endoribonuclease Dicer homolog 3b... | 455 | 2e-40 | 168 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | | 4 | Q09884 | 1374 | DCR1_SCHPO Protein Dicer OS=Schizosaccharomyc... | 482 | 4e-37 | 157 | 29 | 47 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005720; C:nuclear heterochromatin; IC:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:PomBase.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0031048; P:chromatin silencing by small RNA; TAS:PomBase.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0035389; P:establishment of chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0035196; P:production of miRNAs involved in gene silencing by miRNA; IDA:PomBase.::GO:0030422; P:production of siRNA involved in RNA interference; TAS:PomBase.::GO:0090052; P:regulation of chromatin silencing at centromere; IMP:PomBase.::GO:0051983; P:regulation of chromosome segregation; IMP:PomBase.::GO:0051570; P:regulation of histone H3-K9 methylation; IMP:PomBase. | 5 | Q3EBC8 | 1388 | DCL2_ARATH Endoribonuclease Dicer homolog 2 O... | 367 | 8e-35 | 149 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0051607; P:defense response to virus; IMP:TAIR.::GO:0010216; P:maintenance of DNA methylation; IMP:TAIR.::GO:0010267; P:production of ta-siRNAs involved in RNA interference; IMP:TAIR. | 6 | Q10HL3 | 1410 | DCL2A_ORYSJ Endoribonuclease Dicer homolog 2a... | 486 | 2e-34 | 148 | 29 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 7 | Q9SP32 | 1909 | DCL1_ARATH Endoribonuclease Dicer homolog 1 O... | 475 | 3e-34 | 148 | 27 | 43 | GO:0010445; C:nuclear dicing body; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:TAIR.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:TAIR.::GO:0009880; P:embryonic pattern specification; IMP:TAIR.::GO:0009908; P:flower development; TAS:TAIR.::GO:0035279; P:mRNA cleavage involved in gene silencing by miRNA; IMP:TAIR.::GO:0031053; P:primary miRNA processing; TAS:TAIR.::GO:0010599; P:production of lsiRNA involved in RNA interference; IMP:TAIR.::GO:0010267; P:production of ta-siRNAs involved in RNA interference; IMP:TAIR.::GO:2000034; P:regulation of seed maturation; IMP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.::GO:0009616; P:virus induced gene silencing; IMP:TAIR. | 8 | Q7S8J7 | 1584 | DCL1_NEUCR Dicer-like protein 1 OS=1257 / FGS... | 196 | 4e-34 | 147 | 41 | 60 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 9 | Q69LX2 | 1377 | DCL2B_ORYSJ Endoribonuclease Dicer homolog 2b... | 485 | 6e-34 | 147 | 29 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 10 | Q9LXW7 | 1580 | DCL3_ARATH Endoribonuclease Dicer homolog 3 O... | 439 | 4e-33 | 144 | 28 | 46 | GO:0005730; C:nucleolus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010216; P:maintenance of DNA methylation; IMP:TAIR.::GO:0010267; P:production of ta-siRNAs involved in RNA interference; IMP:TAIR. | 11 | Q8LMR2 | 1883 | DCL1_ORYSJ Endoribonuclease Dicer homolog 1 O... | 233 | 1e-31 | 139 | 36 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IMP:UniProtKB.::GO:0035196; P:production of miRNAs involved in gene silencing by miRNA; IMP:UniProtKB. | 12 | A1C9M6 | 1389 | DCL2_ASPCL Dicer-like protein 2 OS=3887 / NRR... | 394 | 1e-30 | 136 | 30 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 13 | Q0UL22 | 1399 | DCL2_PHANO Dicer-like protein 2 OS=(Glume blo... | 417 | 2e-29 | 132 | 30 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 14 | P84634 | 1702 | DCL4_ARATH Dicer-like protein 4 OS=Arabidopsi... | 422 | 4e-29 | 131 | 26 | 45 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0051607; P:defense response to virus; IMP:TAIR.::GO:0010216; P:maintenance of DNA methylation; IMP:TAIR.::GO:0010599; P:production of lsiRNA involved in RNA interference; IMP:TAIR.::GO:0010267; P:production of ta-siRNAs involved in RNA interference; IMP:TAIR.::GO:0010050; P:vegetative phase change; IMP:TAIR. | 15 | O95786 | 925 | DDX58_HUMAN Probable ATP-dependent RNA helica... | 526 | 1e-27 | 125 | 27 | 45 | GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003727; F:single-stranded RNA binding; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0009597; P:detection of virus; IDA:BHF-UCL.::GO:0045087; P:innate immune response; IMP:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0002230; P:positive regulation of defense response to virus by host; IMP:UniProtKB.::GO:0032727; P:positive regulation of interferon-alpha production; IDA:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IC:BHF-UCL.::GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0030334; P:regulation of cell migration; IDA:UniProtKB.::GO:0034344; P:regulation of type III interferon production; TAS:UniProtKB.::GO:0039529; P:RIG-I signaling pathway; IMP:UniProtKB. | 16 | Q0CEI2 | 1377 | DCL2_ASPTN Dicer-like protein 2 OS=Aspergillu... | 455 | 7e-26 | 120 | 27 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 17 | Q2VF19 | 1548 | DCL1_CRYPA Dicer-like protein 1 OS=parasitica... | 218 | 6e-25 | 117 | 38 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 18 | Q58900 | 778 | Y1505_METJA Putative ATP-dependent RNA helica... | 521 | 1e-24 | 115 | 25 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:InterPro. | 19 | O74758 | 213 | YBE3_SCHPO Uncharacterized protein C17D11.03c... | 201 | 2e-24 | 108 | 32 | 53 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0051920; F:peroxiredoxin activity; IEA:InterPro. | | | | | | | | | | | 20 | Q5N870 | 1651 | DCL3A_ORYSJ Endoribonuclease Dicer homolog 3a... | 293 | 3e-23 | 112 | 30 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 21 | P47148 | 283 | YJ81_YEAST Uncharacterized protein YJR111C OS... | 263 | 9e-22 | 102 | 28 | 42 | GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0051920; F:peroxiredoxin activity; IEA:InterPro. | | | | | | | | | | | 22 | A4RHU9 | 1485 | DCL2_MAGO7 Dicer-like protein 2 OS=blast fung... | 374 | 1e-21 | 106 | 29 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 23 | Q5A1A0 | 1187 | MPH1_CANAL ATP-dependent DNA helicase MPH1 OS... | 567 | 9e-21 | 103 | 25 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 24 | A2QX45 | 1362 | DCL22_ASPNC Dicer-like protein 2-2 OS=Aspergi... | 450 | 1e-20 | 103 | 25 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 25 | Q9HE09 | 783 | MFH2_SCHPO Putative ATP-dependent RNA helicas... | 514 | 2e-19 | 99 | 24 | 43 | GO:0005730; C:nucleolus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IC:PomBase.::GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; ISS:PomBase.::GO:0033567; P:DNA replication, Okazaki fragment processing; ISS:PomBase. | 26 | A7EFH4 | 1235 | MPH1_SCLS1 ATP-dependent DNA helicase mph1 OS... | 539 | 1e-16 | 90.1 | 24 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 27 | A1WMW1 | 247 | RNC_VEREI Ribonuclease 3 OS=Verminephrobacter... | 193 | 0.00000000000001 | 80.1 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:EC.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0016075; P:rRNA catabolic process; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 28 | Q9BYX4 | 1025 | IFIH1_HUMAN Interferon-induced helicase C dom... | 243 | 0.00000000000004 | 82 | 31 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.::GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0039528; P:cytoplasmic pattern recognition receptor signaling pathway in response to virus; TAS:UniProtKB.::GO:0009597; P:detection of virus; TAS:BHF-UCL.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0032727; P:positive regulation of interferon-alpha production; IMP:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0034344; P:regulation of type III interferon production; TAS:UniProtKB. | 29 | Q99J87 | 678 | DHX58_MOUSE Probable ATP-dependent RNA helica... | 220 | 0.00000000000009 | 80.5 | 30 | 48 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045824; P:negative regulation of innate immune response; IMP:UniProtKB.::GO:0039534; P:negative regulation of MDA-5 signaling pathway; ISS:UniProtKB.::GO:0039536; P:negative regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; IMP:UniProtKB.::GO:1900245; P:positive regulation of MDA-5 signaling pathway; IMP:UniProtKB.::GO:1900246; P:positive regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; IMP:UniProtKB. | 30 | O01326 | 1086 | RNC_CAEEL Ribonuclease 3 OS=Caenorhabditis el... | 248 | 0.00000000000009 | 80.9 | 27 | 43 | GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IMP:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0031053; P:primary miRNA processing; IMP:UniProtKB.::GO:0016075; P:rRNA catabolic process; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0019953; P:sexual reproduction; IMP:UniProtKB. | 31 | Q7SCC1 | 1540 | DCL2_NEUCR Dicer-like protein 2 OS=1257 / FGS... | 223 | 0.0000000000001 | 80.1 | 30 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. |
