rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9ERD9 | 407 | I23O1_RAT Indoleamine 2,3-dioxygenase 1 OS=Ra... | 444 | 1e-39 | 152 | 27 | 45 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0016597; F:amino acid binding; IDA:RGD.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:RGD.::GO:0019825; F:oxygen binding; IDA:RGD. | | | | | | | | | | GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:RGD. | 2 | P47125 | 453 | I23O_YEAST Indoleamine 2,3-dioxygenase family... | 422 | 2e-39 | 152 | 29 | 47 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; NAS:SGD.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; NAS:SGD. | | | | | | | | | | GO:0034354; P:de novo NAD biosynthetic process from tryptophan; IGI:SGD. | 3 | P14902 | 403 | I23O1_HUMAN Indoleamine 2,3-dioxygenase 1 OS=... | 430 | 2e-38 | 149 | 29 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome. | | | | | | | | | | GO:0007565; P:female pregnancy; TAS:ProtInc.::GO:0006569; P:tryptophan catabolic process; TAS:Reactome. | 4 | P28776 | 407 | I23O1_MOUSE Indoleamine 2,3-dioxygenase 1 OS=... | 427 | 3e-38 | 148 | 28 | 46 | GO:0030485; C:smooth muscle contractile fiber; IDA:MGI.::GO:0032421; C:stereocilium bundle; IDA:MGI. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; IDA:MGI. | | | | | | | | | | GO:0007610; P:behavior; IMP:MGI.::GO:0002534; P:cytokine production involved in inflammatory response; IMP:MGI.::GO:0034276; P:kynurenic acid biosynthetic process; IMP:MGI.::GO:0033555; P:multicellular organismal response to stress; IMP:MGI.::GO:0046007; P:negative regulation of activated T cell proliferation; IMP:MGI.::GO:0032693; P:negative regulation of interleukin-10 production; IMP:MGI.::GO:0070233; P:negative regulation of T cell apoptotic process; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0002678; P:positive regulation of chronic inflammatory response; IMP:MGI.::GO:0032735; P:positive regulation of interleukin-12 production; IMP:MGI.::GO:0002666; P:positive regulation of T cell tolerance induction; IMP:MGI.::GO:0002830; P:positive regulation of type 2 immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.::GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:MGI. | 5 | Q8R0V5 | 398 | I23O2_MOUSE Indoleamine 2,3-dioxygenase 2 OS=... | 425 | 8e-36 | 141 | 31 | 45 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | | 6 | Q6ZQW0 | 407 | I23O2_HUMAN Indoleamine 2,3-dioxygenase 2 OS=... | 427 | 2e-35 | 140 | 31 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:UniProtKB.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome. | | | | | | | | | | GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:UniProtKB. | 7 | P51537 | 378 | MYG_HALMK Myoglobin OS=Haliotis madaka (Giant... | 373 | 3e-23 | 103 | 26 | 43 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 8 | Q01966 | 378 | MYG_HALDV Myoglobin OS=Haliotis diversicolor ... | 372 | 4e-19 | 92.4 | 25 | 42 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | Q11C97 | 449 | AROA_MESSB 3-phosphoshikimate 1-carboxyvinylt... | 102 | 1.4 | 35 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003866; F:3-phosphoshikimate 1-carboxyvinyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW. | 10 | Q2XXQ5 | 237 | CRVP2_DISTY Cysteine-rich secretory protein D... | 70 | 7.8 | 32.3 | 31 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019855; F:calcium channel inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 11 | Q2XXQ6 | 237 | CRVP1_DISTY Cysteine-rich secretory protein D... | 70 | 9.5 | 32 | 31 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019855; F:calcium channel inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | |