| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | O00329 | 1044 | PK3CD_HUMAN Phosphatidylinositol 4,5-bisphosp... | 240 | 5e-16 | 87.8 | 29 | 45 | GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0035754; P:B cell chemotaxis; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0001816; P:cytokine production; TAS:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0002551; P:mast cell chemotaxis; TAS:UniProtKB.::GO:0043303; P:mast cell degranulation; TAS:UniProtKB.::GO:0060374; P:mast cell differentiation; TAS:UniProtKB.::GO:0035747; P:natural killer cell chemotaxis; TAS:UniProtKB.::GO:0001779; P:natural killer cell differentiation; TAS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; TAS:UniProtKB.::GO:0072672; P:neutrophil extravasation; TAS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0006468; P:protein phosphorylation; NAS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; TAS:UniProtKB.::GO:0010818; P:T cell chemotaxis; TAS:UniProtKB.::GO:0030217; P:T cell differentiation; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:UniProtKB. | 62 | Q8N8J0 | 262 | PI4P1_HUMAN Putative phosphatidylinositol 4-k... | 173 | 0.002 | 45.4 | 22 | 43 | | | | | | | | | | | | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 63 | P0C5E7 | 1159 | AGE1_CAEBR Phosphatidylinositol 3-kinase age-... | 219 | 0.0000000000007 | 77.8 | 26 | 46 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007568; P:aging; ISS:UniProtKB.::GO:0040024; P:dauer larval development; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 64 | Q92213 | 1020 | VPS34_CANAX Phosphatidylinositol 3-kinase VPS... | 56 | 0.0000004 | 58.9 | 46 | 64 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 65 | Q8SR56 | 458 | VPS34_ENCCU Probable phosphatidylinositol 3-k... | 263 | 0.00000009 | 60.1 | 23 | 44 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 66 | Q5UR69 | 701 | YL615_MIMIV Putative phosphatidylinositol kin... | 232 | 0.0000003 | 59.3 | 22 | 42 | | | | | | | | | | | GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 67 | Q6CAD2 | 2282 | ATM_YARLI Serine/threonine-protein kinase TEL... | 211 | 0.000003 | 56.2 | 30 | 44 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 68 | P38110 | 2787 | ATM_YEAST Serine/threonine-protein kinase TEL... | 171 | 0.0002 | 50.1 | 25 | 41 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IC:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0042162; F:telomeric DNA binding; IDA:SGD. | | | | | | | | | | GO:0006975; P:DNA damage induced protein phosphorylation; IMP:SGD.::GO:0006302; P:double-strand break repair; IMP:SGD.::GO:0016572; P:histone phosphorylation; IMP:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD. | 69 | Q9N3Q4 | 649 | ATM_CAEEL Serine/threonine-protein kinase ATM... | 189 | 0.002 | 46.6 | 24 | 39 | GO:0000785; C:chromatin; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 70 | Q9VXG8 | 2517 | ATR_DROME Serine/threonine-protein kinase ATR... | 161 | 0.002 | 47 | 27 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0030261; P:chromosome condensation; IGI:FlyBase.::GO:0000076; P:DNA replication checkpoint; IMP:FlyBase.::GO:0045002; P:double-strand break repair via single-strand annealing; IMP:FlyBase.::GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; TAS:FlyBase.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007444; P:imaginal disc development; TAS:FlyBase.::GO:0007133; P:meiotic anaphase I; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0007088; P:regulation of mitosis; IMP:FlyBase.::GO:0007348; P:regulation of syncytial blastoderm mitotic cell cycle; TAS:FlyBase.::GO:0009314; P:response to radiation; TAS:FlyBase.::GO:0000723; P:telomere maintenance; IGI:FlyBase. | 71 | Q4WVM7 | 2796 | ATM_ASPFU Serine/threonine-protein kinase tel... | 225 | 0.009 | 44.7 | 24 | 38 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 72 | Q5BHE2 | 2793 | ATM_EMENI Serine/threonine-protein kinase tel... | 229 | 0.01 | 44.7 | 24 | 36 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 73 | Q2U639 | 2925 | ATM_ASPOR Serine/threonine-protein kinase tel... | 229 | 0.011 | 44.3 | 24 | 38 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 74 | P0CP60 | 2967 | ATM_CRYNJ Serine/threonine-protein kinase TEL... | 57 | 0.028 | 43.1 | 39 | 61 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 75 | P0CP61 | 2968 | ATM_CRYNB Serine/threonine-protein kinase TEL... | 57 | 0.029 | 43.1 | 39 | 61 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 76 | Q86C65 | 2380 | TOR_DICDI Target of rapamycin OS=Dictyosteliu... | 40 | 0.082 | 41.6 | 45 | 68 | GO:0031932; C:TORC2 complex; IPI:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW. | 77 | Q02099 | 2386 | RAD3_SCHPO Protein kinase rad3 OS=Schizosacch... | 96 | 0.092 | 41.2 | 30 | 52 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0000228; C:nuclear chromosome; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031573; P:intra-S DNA damage checkpoint; IDA:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; NAS:PomBase. | 78 | Q9DE14 | 2654 | ATR_XENLA Serine/threonine-protein kinase atr... | 92 | 0.1 | 41.2 | 33 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB. | 79 | O14356 | 2335 | TOR1_SCHPO Phosphatidylinositol 3-kinase tor1... | 174 | 0.11 | 41.2 | 23 | 40 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007569; P:cell aging; TAS:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; IMP:PomBase.::GO:0043091; P:L-arginine import; IMP:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:PomBase.::GO:0060357; P:regulation of leucine import; IMP:PomBase.::GO:0009266; P:response to temperature stimulus; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase. | 80 | Q9JKK8 | 2635 | ATR_MOUSE Serine/threonine-protein kinase ATR... | 92 | 0.16 | 40.4 | 33 | 49 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 81 | Q13535 | 2644 | ATR_HUMAN Serine/threonine-protein kinase ATR... | 92 | 0.16 | 40.4 | 33 | 49 | GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0032405; F:MutLalpha complex binding; IDA:MGI.::GO:0032407; F:MutSalpha complex binding; IDA:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0007049; P:cell cycle; TAS:ProtInc.::GO:0071480; P:cellular response to gamma radiation; IDA:BHF-UCL.::GO:0034644; P:cellular response to UV; IMP:BHF-UCL.::GO:0000077; P:DNA damage checkpoint; IDA:UniProtKB.::GO:0006281; P:DNA repair; TAS:Reactome.::GO:0006260; P:DNA replication; TAS:Reactome.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0008156; P:negative regulation of DNA replication; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0090399; P:replicative senescence; IMP:BHF-UCL. | 82 | Q751J3 | 2768 | ATM_ASHGO Serine/threonine-protein kinase TEL... | 97 | 0.17 | 40.4 | 29 | 43 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 83 | Q0DJS1 | 2465 | TOR_ORYSJ Serine/threonine-protein kinase TOR... | 174 | 0.24 | 40 | 24 | 37 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 84 | Q70PP2 | 3218 | SMG1_DROME Serine/threonine-protein kinase Sm... | 70 | 0.26 | 40 | 34 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.::GO:0050808; P:synapse organization; IDA:FlyBase.::GO:0048489; P:synaptic vesicle transport; IDA:FlyBase. | 85 | O74630 | 2812 | ATM_SCHPO Serine/threonine-protein kinase tel... | 193 | 0.51 | 38.9 | 25 | 37 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; NAS:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016572; P:histone phosphorylation; IGI:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase. | 86 | Q6PQD5 | 3057 | ATM_PIG Serine-protein kinase ATM OS=Sus scro... | 128 | 0.69 | 38.5 | 27 | 46 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0071044; P:histone mRNA catabolic process; ISS:UniProtKB.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; ISS:UniProtKB.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0006412; P:translation; IEA:InterPro. | 87 | Q95Q95 | 2697 | TOR_CAEEL Target of rapamycin homolog OS=Caen... | 40 | 0.8 | 38.1 | 43 | 65 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. | | | | | | | | | | GO:0000492; P:box C/D snoRNP assembly; IMP:WormBase.::GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006629; P:lipid metabolic process; IMP:WormBase.::GO:0045727; P:positive regulation of translation; IMP:WormBase.::GO:0009408; P:response to heat; IMP:WormBase.::GO:0031929; P:TOR signaling cascade; IMP:WormBase.::GO:0006412; P:translation; IMP:WormBase. | 88 | Q62388 | 3066 | ATM_MOUSE Serine-protein kinase ATM OS=Mus mu... | 126 | 0.83 | 38.1 | 29 | 48 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IGI:MGI.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:MGI.::GO:0006281; P:DNA repair; IDA:MGI.::GO:0007292; P:female gamete generation; IMP:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0071044; P:histone mRNA catabolic process; ISS:UniProtKB.::GO:0042159; P:lipoprotein catabolic process; IGI:MGI.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IGI:MGI.::GO:0043525; P:positive regulation of neuron apoptotic process; IGI:MGI.::GO:0002331; P:pre-B cell allelic exclusion; IMP:UniProtKB.::GO:0001756; P:somitogenesis; IGI:MGI. | 89 | Q9JLN9 | 2549 | MTOR_MOUSE Serine/threonine-protein kinase mT... | 40 | 1.2 | 37.7 | 43 | 65 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0043022; F:ribosome binding; IDA:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; IDA:UniProtKB.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0045792; P:negative regulation of cell size; IGI:MGI.::GO:0016242; P:negative regulation of macroautophagy; IMP:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:MGI.::GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:MGI.::GO:0045859; P:regulation of protein kinase activity; IGI:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI.::GO:0043200; P:response to amino acid stimulus; IDA:MGI.::GO:0032868; P:response to insulin stimulus; IDA:MGI.::GO:0031529; P:ruffle organization; IDA:MGI. | 90 | Q9VK45 | 2470 | TOR_DROME Target of rapamycin OS=Drosophila m... | 68 | 1.2 | 37.7 | 32 | 57 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; NAS:FlyBase.::GO:0043621; F:protein self-association; IDA:FlyBase. | | | | | | | | | | GO:0006914; P:autophagy; IMP:FlyBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0009594; P:detection of nutrient; TAS:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0032456; P:endocytic recycling; IDA:FlyBase.::GO:0008406; P:gonad development; IMP:FlyBase.::GO:0035264; P:multicellular organism growth; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; NAS:FlyBase.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; TAS:FlyBase.::GO:0046622; P:positive regulation of organ growth; TAS:FlyBase.::GO:0001934; P:positive regulation of protein phosphorylation; IGI:FlyBase.::GO:0090070; P:positive regulation of ribosome biogenesis; IMP:FlyBase.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IGI:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase. | 91 | P42346 | 2549 | MTOR_RAT Serine/threonine-protein kinase mTOR... | 40 | 1.2 | 37.7 | 43 | 65 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0070438; C:mTOR-FKBP12-rapamycin complex; IDA:RGD.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0031931; C:TORC1 complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:RGD.::GO:0045792; P:negative regulation of cell size; IMP:MGI.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:RGD.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IMP:RGD.::GO:0043610; P:regulation of carbohydrate utilization; IDA:RGD.::GO:0031998; P:regulation of fatty acid beta-oxidation; IDA:RGD.::GO:0005979; P:regulation of glycogen biosynthetic process; IDA:RGD.::GO:0032095; P:regulation of response to food; IDA:RGD. |
