| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P56287 | 678 | EI2BE_SCHPO Probable translation initiation f... | 679 | 2e-160 | 486 | 41 | 61 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:PomBase. | | | | | | | | | | GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 2 | P87163 | 732 | EI2BE_CANAL Translation initiation factor eIF... | 707 | 3e-128 | 404 | 35 | 54 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:CGD. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:CGD. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 3 | P32501 | 712 | EI2BE_YEAST Translation initiation factor eIF... | 679 | 7e-125 | 395 | 37 | 57 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:SGD.::GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:SGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IGI:SGD. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; IDA:SGD.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 4 | Q54RF3 | 707 | EI2BE_DICDI Translation initiation factor eIF... | 666 | 6e-103 | 337 | 32 | 55 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase.::GO:0043614; C:multi-eIF complex; ISS:dictyBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:dictyBase.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 5 | Q8CHW4 | 717 | EI2BE_MOUSE Translation initiation factor eIF... | 668 | 1e-96 | 320 | 32 | 50 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 6 | P47823 | 721 | EI2BE_RABIT Translation initiation factor eIF... | 667 | 1e-94 | 315 | 31 | 50 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 7 | Q64350 | 716 | EI2BE_RAT Translation initiation factor eIF-2... | 711 | 4e-94 | 313 | 31 | 49 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; TAS:RGD.::GO:0031369; F:translation initiation factor binding; IDA:RGD. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 8 | Q13144 | 721 | EI2BE_HUMAN Translation initiation factor eIF... | 406 | 2e-82 | 282 | 36 | 57 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.::GO:0031369; F:translation initiation factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0014002; P:astrocyte development; IMP:UniProtKB.::GO:0042552; P:myelination; IMP:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; IMP:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 9 | P37820 | 359 | MPG1_SULAC Putative mannose-1-phosphate guany... | 400 | 9e-19 | 92 | 24 | 45 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 10 | P56288 | 458 | EI2BG_SCHPO Probable translation initiation f... | 417 | 0.000000000000002 | 82.8 | 23 | 39 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase.::GO:0005840; C:ribosome; ISS:PomBase. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:PomBase. | | | | | | | | | | GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase. | 11 | A5PJI7 | 452 | EI2BG_BOVIN Translation initiation factor eIF... | 446 | 0.0000000000005 | 75.5 | 24 | 39 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB. | 12 | Q68EQ1 | 360 | GMPPB_XENTR Mannose-1-phosphate guanyltransfe... | 411 | 0.00000000007 | 68.2 | 24 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 13 | P70541 | 452 | EI2BG_RAT Translation initiation factor eIF-2... | 150 | 0.007 | 43.1 | 23 | 49 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:RGD.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB. | 14 | Q9NR50 | 452 | EI2BG_HUMAN Translation initiation factor eIF... | 151 | 0.012 | 42.4 | 23 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032057; P:negative regulation of translational initiation in response to stress; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB. | 15 | Q922H4 | 420 | GMPPA_MOUSE Mannose-1-phosphate guanyltransfe... | 388 | 0.0000000004 | 65.9 | 24 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 16 | Q54FQ8 | 440 | EI2BG_DICDI Translation initiation factor eIF... | 432 | 0.001 | 45.4 | 21 | 38 | | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 17 | Q4R6T3 | 452 | EI2BG_MACFA Translation initiation factor eIF... | 150 | 0.02 | 41.6 | 23 | 45 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB. | 18 | A2VD83 | 360 | GMPBB_XENLA Mannose-1-phosphate guanyltransfe... | 411 | 0.0000000007 | 65.1 | 24 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 19 | Q68EY9 | 360 | GMPBA_XENLA Mannose-1-phosphate guanyltransfe... | 411 | 0.0000000007 | 65.1 | 24 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 20 | B0CM52 | 420 | GMPPA_PAPAN Mannose-1-phosphate guanyltransfe... | 404 | 0.000000009 | 61.6 | 24 | 40 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 21 | Q96IJ6 | 420 | GMPPA_HUMAN Mannose-1-phosphate guanyltransfe... | 404 | 0.00000001 | 61.2 | 24 | 40 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.::GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. | 22 | Q5XIC1 | 420 | GMPPA_RAT Mannose-1-phosphate guanyltransfera... | 396 | 0.00000002 | 60.5 | 24 | 41 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 23 | O74484 | 363 | MPG1_SCHPO Mannose-1-phosphate guanyltransfer... | 399 | 0.00000005 | 59.3 | 24 | 40 | GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; ISS:PomBase. | | | | | | | | | | GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0031567; P:cell size control checkpoint; IGI:PomBase.::GO:0000032; P:cell wall mannoprotein biosynthetic process; IC:PomBase.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:PomBase.::GO:0009298; P:GDP-mannose biosynthetic process; IC:PomBase.::GO:0006486; P:protein glycosylation; IMP:PomBase. | 24 | Q8BTZ7 | 360 | GMPPB_MOUSE Mannose-1-phosphate guanyltransfe... | 417 | 0.00000006 | 58.9 | 23 | 41 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 25 | Q752H4 | 361 | MPG1_ASHGO Mannose-1-phosphate guanyltransfer... | 404 | 0.0000003 | 56.6 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 26 | Q6DBU5 | 360 | GMPPB_DANRE Mannose-1-phosphate guanyltransfe... | 401 | 0.0000006 | 55.8 | 23 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 27 | Q2YDJ9 | 360 | GMPPB_BOVIN Mannose-1-phosphate guanyltransfe... | 411 | 0.0000008 | 55.5 | 23 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 28 | Q54K39 | 359 | GMPPB_DICDI Mannose-1-phosphate guanyltransfe... | 404 | 0.0000009 | 55.5 | 24 | 39 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; ISS:dictyBase. | | | | | | | | | | GO:0009298; P:GDP-mannose biosynthetic process; ISS:dictyBase. | 29 | Q9Y5P6 | 360 | GMPPB_HUMAN Mannose-1-phosphate guanyltransfe... | 416 | 0.000001 | 54.7 | 24 | 40 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.::GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. | 30 | Q9M2S0 | 364 | GMPP2_ARATH Probable mannose-1-phosphate guan... | 425 | 0.000008 | 52.4 | 22 | 37 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 31 | B2G4W5 | 243 | AGLF_HALVO UTP--glucose-1-phosphate uridylylt... | 131 | 0.00002 | 50.1 | 27 | 47 | | | | | | | | | | | GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. |
