| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | O55071 | 492 | CP2BJ_MOUSE Cytochrome P450 2B19 OS=Mus muscu... | 285 | 0.000000000008 | 70.9 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 32 | O70537 | 501 | CP3AV_MESAU Cytochrome P450 3A31 OS=Mesocrice... | 242 | 0.000000000009 | 70.9 | 24 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 33 | Q43147 | 464 | C85A1_SOLLC Cytochrome P450 85A1 OS=Solanum l... | 204 | 0.000000000009 | 70.5 | 27 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0016132; P:brassinosteroid biosynthetic process; IEA:UniProtKB-KW. | 34 | P33266 | 449 | CP2E1_MACFA Cytochrome P450 2E1 OS=Macaca fas... | 259 | 0.00000000001 | 70.1 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 35 | Q64406 | 503 | CP3AF_CAVPO Cytochrome P450 3A15 OS=Cavia por... | 190 | 0.00000000001 | 70.5 | 26 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 36 | P51871 | 537 | CP4F6_RAT Cytochrome P450 4F6 OS=Rattus norve... | 214 | 0.00000000001 | 70.5 | 29 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; TAS:RGD.::GO:0006691; P:leukotriene metabolic process; IMP:RGD. | 37 | Q9HBI6 | 524 | CP4FB_HUMAN Cytochrome P450 4F11 OS=Homo sapi... | 177 | 0.00000000001 | 70.5 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; TAS:UniProtKB. | | | | | | | | | | GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 38 | Q9EP75 | 524 | CP4FE_MOUSE Leukotriene-B4 omega-hydroxylase ... | 191 | 0.00000000001 | 70.5 | 30 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IEA:EC. | | | | | | | | | | | 39 | P04800 | 504 | CP3A1_RAT Cytochrome P450 3A1 OS=Rattus norve... | 199 | 0.00000000001 | 70.1 | 27 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD. | 40 | P48421 | 502 | C83A1_ARATH Cytochrome P450 83A1 OS=Arabidops... | 207 | 0.00000000002 | 69.7 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IDA:TAIR. | | | | | | | | | | GO:0019761; P:glucosinolate biosynthetic process; IDA:TAIR. | 41 | P78329 | 520 | CP4F2_HUMAN Leukotriene-B(4) omega-hydroxylas... | 191 | 0.00000000002 | 69.7 | 29 | 46 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:UniProtKB.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IDA:UniProtKB.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0052872; F:tocotrienol omega-hydroxylase activity; IDA:UniProtKB.::GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; IMP:UniProtKB. | | | | | | | | | | GO:0017144; P:drug metabolic process; IMP:UniProtKB.::GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0030195; P:negative regulation of blood coagulation; IMP:UniProtKB.::GO:0032304; P:negative regulation of icosanoid secretion; IMP:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0042360; P:vitamin E metabolic process; IDA:UniProtKB.::GO:0042371; P:vitamin K biosynthetic process; IMP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 42 | Q64417 | 503 | CP3AE_CAVPO Cytochrome P450 3A14 OS=Cavia por... | 190 | 0.00000000002 | 69.7 | 26 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 43 | Q9LSF8 | 515 | C82G1_ARATH Cytochrome P450 82G1 OS=Arabidops... | 185 | 0.00000000002 | 69.7 | 25 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0097008; F:(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity; IDA:TAIR.::GO:0097007; F:4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0046246; P:terpene biosynthetic process; IDA:TAIR. | 44 | O18963 | 495 | CP2E1_BOVIN Cytochrome P450 2E1 OS=Bos taurus... | 262 | 0.00000000002 | 69.3 | 24 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 45 | Q64148 | 503 | CP3AA_MESAU Lithocholate 6-beta-hydroxylase O... | 181 | 0.00000000003 | 69.3 | 23 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033777; F:lithocholate 6beta-hydroxylase activity; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 46 | Q29624 | 503 | CP191_PIG Cytochrome P450 19 type I OS=Sus sc... | 387 | 0.00000000003 | 68.9 | 22 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 47 | P79430 | 503 | CP192_PIG Cytochrome P450 19 type II OS=Sus s... | 367 | 0.00000000003 | 68.9 | 23 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 48 | P33272 | 492 | CP2BC_RAT Cytochrome P450 2B12 OS=Rattus norv... | 276 | 0.00000000003 | 68.9 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 49 | Q8K4D6 | 507 | CP4X1_RAT Cytochrome P450 4X1 OS=Rattus norve... | 267 | 0.00000000003 | 68.9 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 50 | P14580 | 510 | CP4A6_RABIT Cytochrome P450 4A6 OS=Oryctolagu... | 238 | 0.00000000004 | 68.6 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 51 | Q3MID2 | 524 | CP4F3_RAT Leukotriene-B(4) omega-hydroxylase ... | 212 | 0.00000000004 | 68.6 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IEA:EC. | | | | | | | | | | | 52 | Q02928 | 519 | CP4AB_HUMAN Cytochrome P450 4A11 OS=Homo sapi... | 183 | 0.00000000004 | 68.6 | 26 | 48 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 53 | Q54QD2 | 483 | C5171_DICDI Probable cytochrome P450 517A1 OS... | 348 | 0.00000000004 | 68.6 | 22 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 54 | Q9LVD2 | 502 | C71BA_ARATH Cytochrome P450 71B10 OS=Arabidop... | 259 | 0.00000000004 | 68.6 | 24 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 55 | Q50LE0 | 467 | C85A3_SOLLC Cytochrome P450 85A3 OS=Solanum l... | 193 | 0.00000000005 | 68.2 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 56 | Q9V4T5 | 531 | CP4E1_DROME Probable cytochrome P450 4e1 OS=D... | 238 | 0.00000000005 | 68.6 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 57 | P11371 | 487 | CP2C4_RABIT Cytochrome P450 2C4 OS=Oryctolagu... | 258 | 0.00000000005 | 68.2 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 58 | Q9GJX5 | 504 | CP4AL_PIG Taurochenodeoxycholic 6 alpha-hydro... | 269 | 0.00000000005 | 68.2 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC. | | | | | | | | | | | 59 | Q69FB6 | 503 | CP19A_LAGAC Cytochrome P450 19A1 OS=Lagenorhy... | 400 | 0.00000000007 | 67.8 | 21 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 60 | P05183 | 504 | CP3A2_RAT Cytochrome P450 3A2 OS=Rattus norve... | 197 | 0.00000000007 | 67.8 | 28 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:RGD. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD. | 61 | P14581 | 511 | CP4A7_RABIT Cytochrome P450 4A7 OS=Oryctolagu... | 238 | 0.00000000008 | 67.8 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | |
