| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q4WQ08 | 785 | ADMB_ASPFU Disintegrin and metalloproteinase ... | 762 | 1e-126 | 404 | 36 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 2 | D4B1G0 | 799 | ADMB_ARTBC Disintegrin and metalloproteinase ... | 752 | 2e-99 | 332 | 32 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 3 | D4DCV9 | 798 | ADMB_TRIVH Disintegrin and metalloproteinase ... | 752 | 3e-98 | 328 | 32 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 4 | C5FUK3 | 796 | ADMB_ARTOC Disintegrin and metalloproteinase ... | 764 | 4e-94 | 317 | 33 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 5 | O13766 | 512 | MDE10_SCHPO Zinc metalloprotease mde10 OS=Sch... | 431 | 9e-55 | 201 | 34 | 52 | GO:0005619; C:ascospore wall; IDA:PomBase.::GO:0009986; C:cell surface; NAS:PomBase.::GO:0005789; C:endoplasmic reticulum membrane; IDA:PomBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0030476; P:ascospore wall assembly; IMP:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 6 | Q9XSL6 | 776 | ADA28_MACFA Disintegrin and metalloproteinase... | 396 | 5e-31 | 134 | 30 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 7 | A3R0T9 | 611 | VM3_OPHHA Zinc metalloproteinase-disintegrin ... | 380 | 8e-31 | 132 | 29 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 8 | D5LMJ3 | 607 | VM3A_NAJAT Zinc metalloproteinase-disintegrin... | 361 | 2e-30 | 130 | 30 | 45 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 9 | Q10749 | 609 | VM3M1_NAJMO Zinc metalloproteinase mocarhagin... | 367 | 7e-30 | 129 | 29 | 46 | GO:0005576; C:extracellular region; IDA:UniProtKB. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030195; P:negative regulation of blood coagulation; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 10 | A8QL59 | 621 | VM3_NAJAT Zinc metalloproteinase-disintegrin ... | 362 | 7e-29 | 126 | 27 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 11 | Q9UKQ2 | 775 | ADA28_HUMAN Disintegrin and metalloproteinase... | 396 | 1e-28 | 126 | 30 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; TAS:ProtInc. | 12 | Q2UXR0 | 614 | VM3E1_ECHOC Zinc metalloproteinase-disintegri... | 453 | 6e-28 | 123 | 27 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 13 | Q9PVK7 | 600 | VM3_NAJKA Zinc metalloproteinase-disintegrin ... | 362 | 2e-27 | 121 | 28 | 44 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 14 | D3TTC2 | 613 | VM3H_NAJAT Zinc metalloproteinase-disintegrin... | 363 | 3e-27 | 121 | 27 | 45 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 15 | D8VNS0 | 615 | VM3_CERRY Zinc metalloproteinase-disintegrin ... | 360 | 5e-26 | 117 | 28 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 16 | Q61072 | 845 | ADAM9_MOUSE Disintegrin and metalloproteinase... | 417 | 6e-26 | 118 | 29 | 42 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005615; C:extracellular space; IMP:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031233; C:intrinsic to external side of plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0005080; F:protein kinase C binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0051384; P:response to glucocorticoid stimulus; IMP:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL. | 17 | Q9Z1K9 | 827 | ADA17_RAT Disintegrin and metalloproteinase d... | 532 | 6e-26 | 117 | 27 | 41 | GO:0009986; C:cell surface; IDA:RGD. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IMP:RGD.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:RGD.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW. | 18 | Q4VM08 | 616 | VM3VA_MACLB Zinc metalloproteinase-disintegri... | 366 | 8e-26 | 117 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 19 | Q9Z0F8 | 827 | ADA17_MOUSE Disintegrin and metalloproteinase... | 532 | 1e-25 | 117 | 27 | 41 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; TAS:Reactome.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030183; P:B cell differentiation; IMP:BHF-UCL.::GO:0048870; P:cell motility; IMP:BHF-UCL.::GO:0002467; P:germinal center formation; IMP:BHF-UCL.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0051272; P:positive regulation of cellular component movement; IMP:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.::GO:0033025; P:regulation of mast cell apoptotic process; IMP:BHF-UCL.::GO:0042493; P:response to drug; IMP:BHF-UCL.::GO:0048536; P:spleen development; IMP:BHF-UCL.::GO:0033077; P:T cell differentiation in thymus; IMP:BHF-UCL. | 20 | P78325 | 824 | ADAM8_HUMAN Disintegrin and metalloproteinase... | 383 | 1e-25 | 117 | 29 | 42 | GO:0071133; C:alpha9-beta1 integrin-ADAM8 complex; ISS:BHF-UCL.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0032127; C:dense core granule membrane; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL.::GO:0032010; C:phagolysosome; IDA:BHF-UCL.::GO:0002102; C:podosome; IDA:BHF-UCL.::GO:0042581; C:specific granule; IDA:BHF-UCL.::GO:0070820; C:tertiary granule; IDA:BHF-UCL. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:BHF-UCL.::GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0043621; F:protein self-association; TAS:BHF-UCL.::GO:0008270; F:zinc ion binding; TAS:BHF-UCL. | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; ISS:BHF-UCL.::GO:0001525; P:angiogenesis; ISS:BHF-UCL.::GO:0000902; P:cell morphogenesis; ISS:BHF-UCL.::GO:0071456; P:cellular response to hypoxia; IDA:BHF-UCL.::GO:0002523; P:leukocyte migration involved in inflammatory response; ISS:BHF-UCL.::GO:0048247; P:lymphocyte chemotaxis; ISS:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.::GO:0002675; P:positive regulation of acute inflammatory response; ISS:BHF-UCL.::GO:0045780; P:positive regulation of bone resorption; ISS:BHF-UCL.::GO:0045785; P:positive regulation of cell adhesion; ISS:BHF-UCL.::GO:2000418; P:positive regulation of eosinophil migration; ISS:BHF-UCL.::GO:2000415; P:positive regulation of fibronectin-dependent thymocyte migration; ISS:BHF-UCL.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:2000391; P:positive regulation of neutrophil extravasation; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:BHF-UCL.::GO:0010954; P:positive regulation of protein processing; NAS:BHF-UCL.::GO:0050714; P:positive regulation of protein secretion; IC:BHF-UCL.::GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:BHF-UCL.::GO:0070245; P:positive regulation of thymocyte apoptotic process; ISS:BHF-UCL.::GO:2000309; P:positive regulation of tumor necrosis factor (ligand) superfamily member 11 production; ISS:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0022407; P:regulation of cell-cell adhesion; IDA:BHF-UCL. | 21 | Q9JLN6 | 793 | ADA28_MOUSE Disintegrin and metalloproteinase... | 454 | 1e-25 | 116 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 22 | A8QL48 | 605 | VM3_BUNFA Zinc metalloproteinase-disintegrin ... | 358 | 1e-25 | 115 | 29 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 23 | Q05910 | 826 | ADAM8_MOUSE Disintegrin and metalloproteinase... | 362 | 2e-25 | 116 | 30 | 45 | GO:0071133; C:alpha9-beta1 integrin-ADAM8 complex; IDA:BHF-UCL.::GO:0032127; C:dense core granule membrane; ISS:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:BHF-UCL.::GO:0032010; C:phagolysosome; ISS:BHF-UCL.::GO:0002102; C:podosome; ISS:BHF-UCL.::GO:0042581; C:specific granule; ISS:BHF-UCL.::GO:0070820; C:tertiary granule; ISS:BHF-UCL. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:BHF-UCL.::GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.::GO:0005178; F:integrin binding; TAS:BHF-UCL.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:BHF-UCL. | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; IDA:BHF-UCL.::GO:0001525; P:angiogenesis; IDA:BHF-UCL.::GO:0043534; P:blood vessel endothelial cell migration; NAS:BHF-UCL.::GO:0000902; P:cell morphogenesis; IMP:BHF-UCL.::GO:0016337; P:cell-cell adhesion; IDA:MGI.::GO:0007160; P:cell-matrix adhesion; TAS:BHF-UCL.::GO:0006944; P:cellular membrane fusion; TAS:BHF-UCL.::GO:0071456; P:cellular response to hypoxia; ISS:BHF-UCL.::GO:0002523; P:leukocyte migration involved in inflammatory response; IMP:BHF-UCL.::GO:0048247; P:lymphocyte chemotaxis; IDA:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; IDA:BHF-UCL.::GO:2000399; P:negative regulation of thymocyte aggregation; NAS:BHF-UCL.::GO:0072675; P:osteoclast fusion; TAS:BHF-UCL.::GO:0002675; P:positive regulation of acute inflammatory response; IMP:BHF-UCL.::GO:0045780; P:positive regulation of bone resorption; IDA:BHF-UCL.::GO:0045785; P:positive regulation of cell adhesion; IDA:BHF-UCL.::GO:0002693; P:positive regulation of cellular extravasation; IMP:BHF-UCL.::GO:2000418; P:positive regulation of eosinophil migration; IMP:BHF-UCL.::GO:2000415; P:positive regulation of fibronectin-dependent thymocyte migration; IMP:BHF-UCL.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:BHF-UCL.::GO:0033089; P:positive regulation of T cell differentiation in thymus; IDA:BHF-UCL.::GO:0070245; P:positive regulation of thymocyte apoptotic process; IMP:BHF-UCL.::GO:2000309; P:positive regulation of tumor necrosis factor (ligand) superfamily member 11 production; IMP:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0045670; P:regulation of osteoclast differentiation; NAS:BHF-UCL.::GO:0048729; P:tissue morphogenesis; TAS:BHF-UCL. | 24 | P78536 | 824 | ADA17_HUMAN Disintegrin and metalloproteinase... | 532 | 2e-25 | 115 | 26 | 41 | GO:0015629; C:actin cytoskeleton; IDA:BHF-UCL.::GO:0016324; C:apical plasma membrane; IDA:BHF-UCL.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL.::GO:0045121; C:membrane raft; IDA:BHF-UCL. | | | | | | | | | | GO:0005178; F:integrin binding; IPI:BHF-UCL.::GO:0005138; F:interleukin-6 receptor binding; IPI:BHF-UCL.::GO:0004222; F:metalloendopeptidase activity; IDA:BHF-UCL.::GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030183; P:B cell differentiation; ISS:BHF-UCL.::GO:0033627; P:cell adhesion mediated by integrin; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:BHF-UCL.::GO:0035625; P:epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway; IMP:BHF-UCL.::GO:0002467; P:germinal center formation; ISS:BHF-UCL.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0032717; P:negative regulation of interleukin-8 production; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0002446; P:neutrophil mediated immunity; IC:BHF-UCL.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0032722; P:positive regulation of chemokine production; IMP:BHF-UCL.::GO:0031659; P:positive regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0010820; P:positive regulation of T cell chemotaxis; IMP:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; ISS:BHF-UCL.::GO:0033025; P:regulation of mast cell apoptotic process; ISS:BHF-UCL.::GO:0042493; P:response to drug; ISS:BHF-UCL.::GO:0055099; P:response to high density lipoprotein particle stimulus; IDA:BHF-UCL.::GO:0001666; P:response to hypoxia; IDA:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; IDA:BHF-UCL.::GO:0048536; P:spleen development; ISS:BHF-UCL.::GO:0033077; P:T cell differentiation in thymus; ISS:BHF-UCL.::GO:0035313; P:wound healing, spreading of epidermal cells; IEP:BHF-UCL. | 25 | Q7LZ61 | 619 | VM3CX_DABRU Coagulation factor X-activating e... | 283 | 3e-25 | 115 | 31 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 26 | Q9BZ11 | 813 | ADA33_HUMAN Disintegrin and metalloproteinase... | 414 | 7e-25 | 114 | 28 | 41 | GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; NAS:UniProtKB. | 27 | Q9R160 | 761 | ADA24_MOUSE Disintegrin and metalloproteinase... | 285 | 2e-24 | 113 | 30 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 28 | Q13443 | 819 | ADAM9_HUMAN Disintegrin and metalloproteinase... | 419 | 2e-24 | 113 | 29 | 42 | GO:0005615; C:extracellular space; ISS:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031233; C:intrinsic to external side of plasma membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0005518; F:collagen binding; IMP:BHF-UCL.::GO:0005178; F:integrin binding; IDA:BHF-UCL.::GO:0043236; F:laminin binding; IMP:BHF-UCL.::GO:0004222; F:metalloendopeptidase activity; IDA:BHF-UCL.::GO:0005080; F:protein kinase C binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0033631; P:cell-cell adhesion mediated by integrin; IEP:BHF-UCL.::GO:0007160; P:cell-matrix adhesion; IMP:BHF-UCL.::GO:0007229; P:integrin-mediated signaling pathway; IC:BHF-UCL.::GO:0030216; P:keratinocyte differentiation; IEP:BHF-UCL.::GO:0042117; P:monocyte activation; IMP:BHF-UCL.::GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; TAS:BHF-UCL.::GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IMP:BHF-UCL.::GO:0051549; P:positive regulation of keratinocyte migration; IMP:BHF-UCL.::GO:0034241; P:positive regulation of macrophage fusion; IMP:BHF-UCL.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; ISS:BHF-UCL.::GO:0050714; P:positive regulation of protein secretion; IDA:BHF-UCL.::GO:0051592; P:response to calcium ion; IMP:BHF-UCL.::GO:0051384; P:response to glucocorticoid stimulus; ISS:BHF-UCL.::GO:0042542; P:response to hydrogen peroxide; IMP:BHF-UCL.::GO:0010042; P:response to manganese ion; IMP:BHF-UCL.::GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL. | 29 | C9E1S0 | 613 | VM3V3_AGKPL Zinc metalloproteinase-disintegri... | 408 | 2e-24 | 112 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 30 | Q8UVG0 | 612 | VM3BE_BOTER Zinc metalloproteinase-disintegri... | 369 | 3e-24 | 111 | 28 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 31 | O14672 | 748 | ADA10_HUMAN Disintegrin and metalloproteinase... | 497 | 3e-24 | 112 | 25 | 40 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005798; C:Golgi-associated vesicle; IDA:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005178; F:integrin binding; NAS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007267; P:cell-cell signaling; NAS:UniProtKB.::GO:0051089; P:constitutive protein ectodomain proteolysis; IDA:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0042117; P:monocyte activation; IMP:BHF-UCL.::GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.::GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0010820; P:positive regulation of T cell chemotaxis; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB.::GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL. |
