| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q8AWI5 | 610 | VM3HA_GLOHA Zinc metalloprotease-disintegrin ... | 280 | 1e-20 | 100 | 30 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 62 | Q28475 | 776 | ADAM7_MACFA Disintegrin and metalloproteinase... | 356 | 1e-20 | 101 | 26 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 63 | Q10743 | 544 | ADA10_RAT Disintegrin and metalloproteinase d... | 497 | 1e-20 | 100 | 24 | 39 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005798; C:Golgi-associated vesicle; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:RGD. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; ISS:UniProtKB.::GO:0043526; P:neuroprotection; IEP:RGD.::GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB.::GO:0045670; P:regulation of osteoclast differentiation; NAS:RGD. | 64 | Q1PHZ4 | 547 | VM3B1_BOTJR Zinc metalloproteinase-disintegri... | 343 | 1e-20 | 100 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 65 | Q98UF9 | 606 | VM3H3_BOTJA Zinc metalloproteinase-disintegri... | 277 | 2e-20 | 100 | 29 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 66 | Q9R157 | 719 | ADA18_MOUSE Disintegrin and metalloproteinase... | 257 | 2e-20 | 100 | 33 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 67 | P20164 | 614 | VM3HB_PROFL Zinc metalloproteinase/disintegri... | 346 | 2e-20 | 99.8 | 27 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 68 | Q60472 | 777 | ADAM5_CAVPO Disintegrin and metalloproteinase... | 289 | 3e-20 | 99.8 | 27 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 69 | A4PBQ9 | 607 | VM3VA_CROAT Zinc metalloproteinase-disintegri... | 444 | 3e-20 | 99 | 24 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 70 | Q8JIR2 | 609 | VM3HA_PROFL Zinc metalloproteinase/disintegri... | 400 | 4e-20 | 98.6 | 25 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; TAS:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030195; P:negative regulation of blood coagulation; IDA:UniProtKB.::GO:0006508; P:proteolysis; IDA:UniProtKB. | 71 | Q9QYV0 | 864 | ADA15_RAT Disintegrin and metalloproteinase d... | 367 | 9e-20 | 98.2 | 31 | 44 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; TAS:RGD.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0016337; P:cell-cell adhesion; TAS:RGD.::GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0042246; P:tissue regeneration; IEP:RGD. | 72 | P83912 | 484 | VM2JT_PROJR Zinc metalloproteinase-disintegri... | 343 | 1e-19 | 96.3 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 73 | O77780 | 745 | ADAM2_BOVIN Disintegrin and metalloproteinase... | 380 | 1e-19 | 97.4 | 26 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro. | 74 | Q8JIY1 | 749 | ADA10_XENLA Disintegrin and metalloproteinase... | 491 | 2e-19 | 97.4 | 24 | 40 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005798; C:Golgi-associated vesicle; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB. | 75 | P82942 | 401 | VM3K_NAJKA Hemorrhagic metalloproteinase-disi... | 277 | 2e-19 | 94.7 | 29 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 76 | O35674 | 920 | ADA19_MOUSE Disintegrin and metalloproteinase... | 377 | 2e-19 | 97.1 | 28 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; IMP:MGI.::GO:0006509; P:membrane protein ectodomain proteolysis; IMP:MGI. | 77 | Q9R159 | 760 | ADA25_MOUSE Disintegrin and metalloproteinase... | 346 | 3e-19 | 96.7 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 78 | Q9H013 | 955 | ADA19_HUMAN Disintegrin and metalloproteinase... | 409 | 4e-19 | 96.3 | 27 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 79 | O43506 | 726 | ADA20_HUMAN Disintegrin and metalloproteinase... | 366 | 5e-19 | 95.5 | 28 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007338; P:single fertilization; TAS:ProtInc. | 80 | Q92043 | 419 | VM3AA_CROAT Zinc metalloproteinase-disintegri... | 364 | 6e-19 | 93.6 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 81 | Q9UKJ8 | 722 | ADA21_HUMAN Disintegrin and metalloproteinase... | 301 | 6e-19 | 95.1 | 29 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007338; P:single fertilization; TAS:ProtInc. | 82 | D3TTC1 | 593 | VM3KL_NAJAT Zinc metalloproteinase-disintegri... | 277 | 8e-19 | 94.7 | 29 | 44 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 83 | O43184 | 909 | ADA12_HUMAN Disintegrin and metalloproteinase... | 397 | 8e-19 | 95.1 | 29 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0007520; P:myoblast fusion; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 84 | Q61824 | 903 | ADA12_MOUSE Disintegrin and metalloproteinase... | 363 | 2e-18 | 94.4 | 30 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 85 | P0C6E8 | 435 | VM3G1_TRIGA Zinc metalloproteinase/disintegri... | 369 | 3e-18 | 91.7 | 26 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 86 | Q8K410 | 754 | ADA32_MOUSE Disintegrin and metalloproteinase... | 361 | 4e-18 | 92.8 | 25 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 87 | Q28483 | 756 | ADAM5_MACFA Disintegrin and metalloproteinase... | 282 | 5e-18 | 92.4 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 88 | Q8AWX7 | 488 | VM2AG_GLOHA Zinc metalloproteinase-disintegri... | 326 | 6e-18 | 91.3 | 26 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 89 | P97776 | 445 | ADA18_RAT Disintegrin and metalloproteinase d... | 255 | 6e-18 | 90.9 | 32 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 90 | P86092 | 324 | VM3LB_BOTLC Zinc metalloproteinase leucurolys... | 231 | 2e-17 | 87.8 | 31 | 45 | GO:0005576; C:extracellular region; IDA:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; IDA:UniProtKB.::GO:0009405; P:pathogenesis; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 91 | D6PXE8 | 593 | VM3B_NAJAT Zinc metalloproteinase-disintegrin... | 277 | 2e-17 | 89.7 | 28 | 43 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. |
