| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | O14672 | 748 | ADA10_HUMAN Disintegrin and metalloproteinase... | 497 | 3e-24 | 112 | 25 | 40 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005798; C:Golgi-associated vesicle; IDA:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005178; F:integrin binding; NAS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007267; P:cell-cell signaling; NAS:UniProtKB.::GO:0051089; P:constitutive protein ectodomain proteolysis; IDA:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0042117; P:monocyte activation; IMP:BHF-UCL.::GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.::GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0010820; P:positive regulation of T cell chemotaxis; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB.::GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL. | 32 | Q7T046 | 612 | VM3CX_MACLB Coagulation factor X-activating e... | 277 | 4e-24 | 111 | 30 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 33 | A8QL49 | 614 | VM3_BUNMU Zinc metalloproteinase-disintegrin ... | 282 | 4e-24 | 111 | 32 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 34 | B8K1W0 | 615 | VM3DK_DABRR Zinc metalloproteinase-disintegri... | 75 | 1.1 | 36.2 | 31 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 35 | O35598 | 749 | ADA10_MOUSE Disintegrin and metalloproteinase... | 497 | 2e-23 | 110 | 25 | 40 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005798; C:Golgi-associated vesicle; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0014069; C:postsynaptic density; IDA:MGI. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; NAS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001701; P:in utero embryonic development; IMP:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; ISS:UniProtKB.::GO:0007220; P:Notch receptor processing; NAS:UniProtKB.::GO:0007219; P:Notch signaling pathway; IMP:UniProtKB.::GO:0006913; P:nucleocytoplasmic transport; NAS:UniProtKB.::GO:0006468; P:protein phosphorylation; IDA:UniProtKB. | 36 | Q10741 | 748 | ADA10_BOVIN Disintegrin and metalloproteinase... | 497 | 3e-23 | 109 | 25 | 39 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005798; C:Golgi-associated vesicle; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB. | 37 | O42138 | 620 | VM3AD_AGKCL Zinc metalloproteinase-disintegri... | 273 | 3e-23 | 108 | 29 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 38 | Q2LD49 | 621 | VM3TM_VIRST Zinc metalloproteinase-disintegri... | 277 | 4e-23 | 108 | 30 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 39 | Q1PS45 | 608 | VM3AK_DEIAC Zinc metalloprotease-disintegrin ... | 446 | 8e-23 | 107 | 25 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 40 | C9E1R8 | 609 | VM3V3_CROVV Zinc metalloproteinase-disintegri... | 444 | 1e-22 | 106 | 24 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 41 | Q90282 | 609 | VM3VB_CROAT Zinc metalloproteinase-disintegri... | 444 | 2e-22 | 106 | 24 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 42 | Q4VM07 | 614 | VM3VB_MACLB Zinc metalloproteinase-disintegri... | 364 | 2e-22 | 106 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 43 | P70505 | 789 | ADAM1_RAT Disintegrin and metalloproteinase d... | 356 | 2e-22 | 106 | 28 | 40 | GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009566; P:fertilization; NAS:RGD.::GO:0006508; P:proteolysis; NAS:UniProtKB. | 44 | Q9W6M5 | 610 | VM3AH_DEIAC Zinc metalloproteinase-disintegri... | 469 | 2e-22 | 105 | 25 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0044421; C:extracellular region part; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 45 | Q8R534 | 806 | ADM1B_MOUSE Disintegrin and metalloproteinase... | 357 | 3e-22 | 106 | 29 | 41 | GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; NAS:UniProtKB.::GO:0007283; P:spermatogenesis; NAS:UniProtKB. | 46 | Q9DGB9 | 610 | VM3V1_CROAT Zinc metalloproteinase-disintegri... | 402 | 3e-22 | 105 | 27 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 47 | Q90ZI3 | 612 | VM3H1_PROFL Zinc metalloproteinase-disintegri... | 280 | 3e-22 | 105 | 31 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 48 | Q60813 | 791 | ADM1A_MOUSE Disintegrin and metalloproteinase... | 356 | 6e-22 | 105 | 28 | 40 | GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0045121; C:membrane raft; IDA:MGI. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007339; P:binding of sperm to zona pellucida; IMP:MGI.::GO:0007342; P:fusion of sperm to egg plasma membrane; NAS:UniProtKB.::GO:0006508; P:proteolysis; NAS:UniProtKB. | 49 | P0C7B0 | 610 | VM3H6_GLOBR Zinc metalloproteinase-disintegri... | 444 | 7e-22 | 104 | 25 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 50 | Q8QG88 | 610 | VM36A_BOTIN Zinc metalloproteinase-disintegri... | 380 | 8e-22 | 103 | 26 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 51 | O93523 | 610 | VM3BP_BOTJA Zinc metalloproteinase-disintegri... | 380 | 9e-22 | 103 | 26 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 52 | Q2UXQ5 | 613 | VM3E2_ECHOC Zinc metalloproteinase-disintegri... | 288 | 1e-21 | 103 | 28 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 53 | O88839 | 864 | ADA15_MOUSE Disintegrin and metalloproteinase... | 369 | 2e-21 | 103 | 30 | 44 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0060317; P:cardiac epithelial to mesenchymal transition; IMP:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 54 | P30431 | 571 | VM3JA_BOTJA Zinc metalloproteinase-disintegri... | 380 | 2e-21 | 102 | 26 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 55 | Q2QA02 | 609 | VM3_CRODD Zinc metalloproteinase-disintegrin ... | 413 | 2e-21 | 102 | 24 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 56 | Q923W9 | 797 | ADA33_MOUSE Disintegrin and metalloproteinase... | 340 | 3e-21 | 102 | 28 | 41 | GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; NAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; NAS:UniProtKB.::GO:0042035; P:regulation of cytokine biosynthetic process; NAS:UniProtKB. | 57 | Q9R158 | 697 | AD26A_MOUSE Disintegrin and metalloproteinase... | 341 | 4e-21 | 102 | 29 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 58 | Q9H2U9 | 754 | ADAM7_HUMAN Disintegrin and metalloproteinase... | 356 | 5e-21 | 102 | 27 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 59 | Q90495 | 616 | VM3E_ECHCA Zinc metalloproteinase-disintegrin... | 357 | 8e-21 | 100 | 26 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 60 | Q13444 | 863 | ADA15_HUMAN Disintegrin and metalloproteinase... | 249 | 9e-21 | 101 | 35 | 47 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.::GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 61 | Q8AWI5 | 610 | VM3HA_GLOHA Zinc metalloprotease-disintegrin ... | 280 | 1e-20 | 100 | 30 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
